-
公开(公告)号：EP4428535A1
公开(公告)日：2024-09-11
申请号：EP23382220.4
申请日：2023-03-09
申请人： Servizo Galego de Saude , Fundación Instituto de Investigación Sanitaria de Santiago de Compostela (FIDIS) , Universidade de Santiago de Compostela
IPC分类号： G01N33/68
CPC分类号： G01N2800/04220130101 , G01N33/6893 , G01N2333/7820130101 , G01N2333/472820130101 , G01N2800/5220130101 , G01N2333/471620130101 , G01N2800/5020130101
摘要： The present invention refers to an in vitro method for the diagnosis, monitoring or prognosis of diabetes or prediabetes; or for screening or selecting patient candidates to be subjected to OGTT, which comprises assessing the percentage of a protein, selected from the group consisting of: Retinol-Binding Protein 4 (Rbp), Alpha-1-acid glycoprotein (Agp) and/or fibronectin (FN), which is bound to glycosaminoglycans (GAGs).
-
公开(公告)号：EP4039251A1
公开(公告)日：2022-08-10
申请号：EP22156931.2
申请日：2019-01-15
申请人： Fundación Instituto de Investigación Sanitaria De Santiago de Compostela (FIDIS) , Servizo Galego De Saúde
发明人： De La Fuente Freire, María , LÓPEZ LÓPEZ, Rafael , López Bouzo, Belén , Vázquez Ríos, Abi Judit , Alonso Nocelo, Marta
IPC分类号： A61K9/107 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/44 , A61K49/00 , A61K49/10 , A61K49/18
摘要： In the present invention, the development of various oil-in-water (O / W) nanoemulsions containing an oil phase or oil core, preferably selected from vitamin E or oleic acid, stabilized by a sphingolipid of the sphingomyelin type, and optionally other lipids such as phospholipids, cholesterol, octadecylamine, DOTAP (N- [1- (2,3-Dioleoyloxy) propyl] -N, N, N-trimethylammonium methyl-sulfate), and PEGylated derivatives (derivatives with polyethylene glycol), for use as a nanotech vehicle , in particular for the management of cancer and metastatic disease, is herein described. Said nanoemulsions can be functionalized with ligands capable of interacting or binding to receptors expressed on the cell membrane of tumor cells, and in particular capable of interacting or binding to receptors expressed on the membrane of primary and/or disseminated or metastatic tumor cells. Also, antitumor drugs or therapeutic biomolecules can be encapsulated in said nanoemulsions and, finally, contrast agents can be incorporated for their use in the in vivo diagnosis in said nanoemulsions.
-
公开(公告)号：EP3740196A1
公开(公告)日：2020-11-25
申请号：EP19700424.5
申请日：2019-01-15
申请人： Fundación Instituto de Investigación Sanitaria De Santiago de Compostela (FIDIS) , Servizo Galego de Saude
-
公开(公告)号：EP4341437A1
公开(公告)日：2024-03-27
申请号：EP22729684.5
申请日：2022-05-20
申请人： Fundación Instituto de Investigación Sanitaria de Santiago de Compostela (FIDIS) , Servizo Galego de Saude , Consorcio Centro de Investigación Biomédica en Red (CIBER) , Universidade de Santiago de Compostela , Universidad De Valladolid , Pronokal Health Group S.L.
发明人： CRUJEIRAS MARTÍNEZ, Ana Belén , CASANUEVA FREIJO, Felipe , GONZÁLEZ IZQUIERDO, Andrea , DE LUIS ROMAN, Daniel Antonio , NÚÑEZ, Maitane , SAJOUX, Ignacio
IPC分类号： C12Q1/6876 , C12Q1/6883
-
公开(公告)号：EP4334473A1
公开(公告)日：2024-03-13
申请号：EP22724466.2
申请日：2022-05-06
申请人： Fundación Instituto De Investigación Sanitaria De Santiago De Compostela (FIDIS) , Servizo Galego de Saúde (SERGAS)
IPC分类号： C12Q1/6883 , G01N33/50
-
公开(公告)号：EP4092137A1
公开(公告)日：2022-11-23
申请号：EP21382469.1
申请日：2021-05-21
申请人： Fundación Instituto de Investigación Sanitaria De Santiago de Compostela (FIDIS) , Servizo Galego de Saude , Consorcio Centro de Investigación Biomédica en Red, M.P. (CIBER) , Universidade de Santiago de Compostela , Universidad De Valladolid , Pronokal Health Group S.L.
发明人： CRUJEIRAS MARTÍNEZ, Ana Belén , CASANUEVA FREIJO, Felipe , GONZÁLEZ IZQUIERDO, Andrea , DE LUIS ROMAN, Daniel Antonio , NÚÑEZ, Maitane , SAJOUX, Ignacio
IPC分类号： C12Q1/6876 , C12Q1/6883
摘要： The present invention refers to an in vitro method for screening and/or selecting genes whose methylation status indicates whether a patient suffering from obesity is responding or will respond to a treatment with VLCKD. Moreover, the present invention refers to an in vitro method for monitoring or predicting whether a patient suffering from obesity is responding or will respond to VLCKD.
-
公开(公告)号：EP4086358A1
公开(公告)日：2022-11-09
申请号：EP21382416.2
申请日：2021-05-07
申请人： Fundación Instituto de Investigación Sanitaria De Santiago de Compostela (FIDIS) , Servizo Galego de Saúde (SERGAS)
IPC分类号： C12Q1/6883 , G01N33/50
摘要： The present invention refers to a method for predicting the response of patients suffering from atrial fibrillation (AF) to catheter ablation treatment, or for the prognosis of patients suffering from AF.
-
公开(公告)号：EP3820455A1
公开(公告)日：2021-05-19
申请号：EP19736745.1
申请日：2019-07-10
申请人： Universidade de Santiago de Compostela , Fundación Instituto de Investigación Sanitaria De Santiago de Compostela (FIDIS) , Servizo Galego de Saude
发明人： ÁLVAREZ GONZÁLEZ, José Víctor , OTERO ESPINAR, Francisco Javier , COUCE PICO, Mª Luz , LUZARDO ÁLVAREZ, Asteria , COLÓN MEJERAS, Cristobal , LEIS TRABAZO, Mª Rosaura
IPC分类号： A61K9/50
-
公开(公告)号：EP4434579A1
公开(公告)日：2024-09-25
申请号：EP23382269.1
申请日：2023-03-23
申请人： Servizo Galego de Saude , Fundación Instituto de Investigación Sanitaria de Santiago de Compostela (FIDIS) , Universidade de Santiago de Compostela
发明人： PAZOS RANDULFE, Yolanda , PÉREZ CAMIÑA, Jesús , DOMÍNGUEZ MUÑOZ, Juan Enrique , CID DÍAZ, Tania , SANTOS ZÁS, Icía , LEAL LÓPEZ, Saúl , CALVIÑO LODEIRO, Andrea
CPC分类号： A61K38/25 , C07K14/60 , A61P5/48 , C07K14/4702 , C12N9/12 , C12Y207/11024
摘要： Obestatin for use as antineoplastic agent in the treatment of pancreatic cancer. The present invention refers to the use obestatin as antineoplastic agent in the treatment of pancreatic cancer.
-
公开(公告)号：EP4410825A1
公开(公告)日：2024-08-07
申请号：EP23382104.0
申请日：2023-02-03
申请人： Servizo Galego de Saude , Fundación Instituto de Investigación Sanitaria de Santiago de Compostela (FIDIS) , Consorcio Centro de Investigacion Biomedica en Red , Universidad Autónoma de Madrid , Universidade De Santiago De Compostela
发明人： DE LA FUENTE FREIRE, María , LORES TOURIÑO, Saínza , SARRIÓ LÓPEZ, José David , GAMEZ CHIACHIO, Manuel , MORENO BUENO, Gema
IPC分类号： C07K14/47 , A61K31/728 , A61K38/17 , A61K47/69 , A61K48/00 , A61K49/00 , A61P35/00 , B82Y5/00 , C12N15/88
CPC分类号： C07K14/47 , C12N15/88 , B82Y5/00 , A61P35/00 , A61K38/1761 , A61K38/1709 , A61K48/005 , A61K31/728 , C07K14/4702 , C07K14/4703 , A61K48/0041 , A61K9/5161
摘要： The present invention generally refers to an isolated polypeptide comprising a fragment of the N-Terminal domain of GSDMB, wherein said fragment is characterized by comprising amino acid sequence 1-233 of the N-Terminal domain of GSDM-B or a functional equivalent thereof or a polynucleotide sequence coding for the said polypeptide, for use in the treatment of cancer.
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.013 秒)
