公开(公告)号：EP3003446A4

公开(公告)日：2017-01-11

申请号：EP14806925

申请日：2014-06-03

Applicant: KLEIN MICHAEL ,  FISHER JOSEPH

Inventor： KLEIN MICHAEL ,  FISHER JOSEPH

IPC: A61B5/083 ,  A61M16/00 ,  A61M16/08 ,  A61M16/10 ,  A61M16/12 ,  A61M16/20

CPC classification number: A61B5/0836 ,  A61B5/0833 ,  A61M16/0045 ,  A61M16/0078 ,  A61M16/026 ,  A61M16/0891 ,  A61M16/104 ,  A61M16/12 ,  A61M16/125 ,  A61M16/208 ,  A61M2016/0027 ,  A61M2016/0036 ,  A61M2016/0039 ,  A61M2202/0208 ,  A61M2202/0225 ,  A61M2202/0241 ,  A61M2205/057 ,  A61M2230/43 ,  A61M2230/432 ,  A61M2230/435 ,  A61M2230/437

公开(公告)号：EP1711455A4

公开(公告)日：2007-11-07

申请号：EP05711747

申请日：2005-01-21

Applicant: UNIV PENNSYLVANIA ,  DEGRADO WILLIAM F ,  LIU DAHUI ,  TEW GREGORY N ,  KLEIN MICHAEL L

Inventor： DEGRADO WILLIAM F ,  LIU DAHUI ,  TEW GREGORY N ,  KLEIN MICHAEL L

IPC: C07C211/00 ,  A61K31/74 ,  C07C211/27 ,  C07C217/58 ,  C07C233/78 ,  C07C279/12

CPC classification number: C07C279/12 ,  A61K31/74 ,  C07C211/27 ,  C07C217/58 ,  C07C233/78

公开(公告)号：EP1535235A1

公开(公告)日：2005-06-01

申请号：EP03755525.7

申请日：2003-05-28

Applicant: The Trustees of The University of Pennsylvania ,  Chen, Bin ,  Klein, Michael L. ,  Degrado, William F.

Inventor： DOERKSEN, Robert,J. ,  CHEN, Bin ,  KLEIN, Michael, L. ,  DEGRADO, William, F.

IPC: G06G7/48

CPC classification number: G06F19/701

Abstract: Methods, systems, and computer program products for computational polymer processing including, without limitation, computational amphiphilic polymer design, conformational energy minimization, generation and refinement of torsional parameters for sub-units of potential polymers, generation of modified force field parameters, and prediction of conformational information for potential polymers. The predicted conformational information is then used to select one or more of the target polymer backbones as candidate amphiphilic polymer backbones for synthesis.

公开(公告)号：EP4310288A1

公开(公告)日：2024-01-24

申请号：EP23166768.4

申请日：2023-04-05

Applicant: Klein, Michael

Inventor： Klein, Michael

IPC: E05F15/41 ,  E05F15/42 ,  E05F15/43 ,  E05F15/605

Abstract: Elektrisch betriebener Klappenbeschlag (1, 20, 30) für ein Möbelelement, insbesondere eine Kücheneinheit (100) mit einer Klappe (16) mit zueinander verschwenkbaren Klappenabschnitten (16A, 16B), einer Antriebseinheit (60) zum Bewegen der Klappe (16) zwischen einer angehobenen und einer abgesenkten Endposition, um eine Fläche des Möbelelements (100) in der abgesenkten Endposition zu bedecken, eine Steuervorrichtung (3) zum Steuern der Antriebseinheit (60), und eine mit der Steuervorrichtung (3) kommunikativ verbundene Detektionseinheit (80; 81 - 83), die ausgebildet ist, ein sich in einer Bewegungsbahn (18) der Klappe (16) befindliches Objekt zu detektieren, wobei die Steuervorrichtung (3) ausgebildet ist, auf Basis eines von der Detektionseinheit (80; 81 - 83) erhaltenen Detektionssignals die Bewegung der Klappe (16) zwischen der angehobenen Endposition und der abgesenkten Endposition zu stoppen.
Es werden des Weiteren ein entsprechendes Verfahren zum Betreiben eines elektrisch betriebenen Klappenbeschlags (1, 20, 30) und ein Speichermedium mit Befehlen zum Ausführen des Verfahrens beschrieben.

公开(公告)号：EP2571422A4

公开(公告)日：2015-09-16

申请号：EP11782808

申请日：2011-05-18

Applicant: FISHER JOSEPH ,  KLEIN MICHAEL ,  DUFFIN JAMES

Inventor： FISHER JOSEPH ,  KLEIN MICHAEL ,  DUFFIN JAMES

IPC: A61B5/08 ,  A61B5/00 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/029 ,  A61B5/083 ,  A61M16/00 ,  A61M16/12 ,  G06F19/00

CPC classification number: A61B5/0205 ,  A61B5/026 ,  A61B5/029 ,  A61B5/0813 ,  A61B5/0836 ,  A61B5/7225 ,  A61B5/7278 ,  A61M16/0057 ,  A61M16/12

公开(公告)号：EP2788063A1

公开(公告)日：2014-10-15

申请号：EP12856262.6

申请日：2012-12-05

Applicant: Klein, Michael ,  Fisher, Joseph ,  Duffin, James ,  Slessarev, Marat ,  Kessler, Cathie ,  Ito, Shoji

Inventor： Klein, Michael ,  Fisher, Joseph ,  Duffin, James ,  Slessarev, Marat ,  Kessler, Cathie ,  Ito, Shoji

IPC: A61M16/10 ,  A61B5/08

CPC classification number: A61M16/0051 ,  A61B5/083 ,  A61B5/0833 ,  A61B5/0836 ,  A61B5/4836 ,  A61M16/0003 ,  A61M16/0069 ,  A61M16/026 ,  A61M16/085 ,  A61M16/0883 ,  A61M16/1005 ,  A61M16/12 ,  A61M16/122 ,  A61M2016/0021 ,  A61M2016/0027 ,  A61M2016/102 ,  A61M2016/1025 ,  A61M2016/103 ,  A61M2205/502 ,  A61M2230/43 ,  A61M2230/432 ,  A61M2230/435

Abstract: A processor obtains input of a logistically attainable end tidal partial pressure of gas X (PetX[i]T) for one or more respective breaths [i] and input of a prospective computation of an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX[i]T for a respective breath [i] using inputs required to utilize a mass balance relationship, wherein one or more values required to control the amount of gas X in a volume of gas delivered to the subject is output from an expression of the mass balance relationship. The mass balance relationship is expressed in a form which takes into account (prospectively), for a respective breath [i], the amount of gas X in the capillaries surrounding the alveoli and the amount of gas X in the alveoli, optionally based on a model of the lung which accounts for those sub-volumes of gas in the lung which substantially affect the alveolar gas X concentration affecting mass transfer.

公开(公告)号：EP2696927A1

公开(公告)日：2014-02-19

申请号：EP12772038.1

申请日：2012-04-12

Applicant: Klein, Michael

Inventor： Klein, Michael

IPC: A61M16/12 ,  A61M16/10 ,  B01F3/02 ,  C01B31/20

CPC classification number: A61M16/12 ,  A61M16/0051 ,  A61M16/026 ,  A61M16/20 ,  A61M16/203 ,  A61M2016/0036 ,  A61M2016/0039 ,  A61M2016/102 ,  A61M2016/103 ,  A61M2202/0225 ,  A61M2205/18 ,  A61M2205/3334 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2230/432 ,  G05D11/138

Abstract: An apparatus, method and system for delivering CO2 into an inspiratory gas stream to formulate a blended respiratory gas in a manner that continuously maintains a target CO2 concentration in a volume of the inspired respiratory gas, for example, over the course of a breath or a volumetrically definable part thereof or a series of partial or full breaths.

公开(公告)号：EP2571422A1

公开(公告)日：2013-03-27

申请号：EP11782808.7

申请日：2011-05-18

Applicant: Fisher, Joseph ,  Klein, Michael ,  Duffin, James

Inventor： Fisher, Joseph ,  Klein, Michael ,  Duffin, James

IPC: A61B5/08 ,  A61B5/026 ,  G06F19/00

CPC classification number: A61B5/0205 ,  A61B5/026 ,  A61B5/029 ,  A61B5/0813 ,  A61B5/0836 ,  A61B5/7225 ,  A61B5/7278 ,  A61M16/0057 ,  A61M16/12

Abstract: A method of controlling a gas delivery apparatus including an apparatus controllable variable using an iterative algorithm to deliver a test gas (TG) for non- invasively determining a subject's pulmonary blood flow comprising iteratively generating and evaluating test values of a iterated variable based on an iterative algorithm in order output a test value of the iterated variable that meets a testcriterion wherein iterative algorithm is characterized in that it defines a test mathematical relationship between the at least one apparatus controllable variable, the iterated variable and an end tidal concentration of test gas attained by setting the apparatus controllable variable, such that the iterative algorithm is determinative of whether iteration on the test value satisfies a test criterion or iteratively generates a progressively refined test value.

Abstract translation: 一种使用迭代算法来控制气体输送装置的方法，所述装置可控变量使用迭代算法递送用于非侵入性地确定受试者的肺血流的测试气体（TG），包括迭代生成并评估迭代变量的测试值 算法，以输出满足测试标准的迭代变量的测试值，其中迭代算法的特征在于其定义了至少一个设备可控变量，迭代变量和获得的测试气体的终端潮汐浓度之间的测试数学关系 通过设置装置可控变量，使得迭代算法确定测试值上的迭代是否满足测试标准或迭代地生成逐渐改进的测试值。

公开(公告)号：EP1030598A4

公开(公告)日：2003-06-18

申请号：EP98960513

申请日：1998-11-23

Applicant: KLEIN MICHAEL ,  ABRAMS MICHAEL E ,  MANNO RICHARD J

Inventor： KLEIN MICHAEL ,  ABRAMS MICHAEL E ,  MANNO RICHARD J

IPC: A61C19/00 ,  A61B6/03 ,  A61B6/14 ,  A61C1/08 ,  A61C8/00 ,  A61C9/00

CPC classification number: A61C8/0089 ,  A61C1/084 ,  A61C9/0053 ,  A61C2201/005

Abstract: The present invention is a surgical template and method for drilling osteotomies (e.g., holes in a jaw bone), and installing one or more dental implants (170) using a surgical template assembly (10). The surgical template assembly (10) is provided with one or more drill guides (120, 130), and one or more dental implant guides (140). The guides are positioned in the template assembly (10) by a computer driven milling machine (60) interfaced with a computer generated image of a patient's jaw bone, and a computer generated simulation of at least one dental implant so that when the template (100) is placed in the patient's mouth a trajectory of the guides in the template (100) into the patient's jawbone corresponds to a trajectory of the computer generated simulation of the dental implant (170) into the computer generated image of the patient's jawbone. Preferably, three fiducial markers (70) provide positional coordination between the CT scan data, the computer generated simulation of the dental implant, and the computer driven milling machine (60).

公开(公告)号：EP0720451A4

公开(公告)日：1997-09-24

申请号：EP94930459

申请日：1994-09-20

Applicant: KLEIN MICHAEL ,  YACKER MILES J

Inventor： KLEIN MICHAEL ,  YACKER MILES J

IPC: A61C1/08 ,  A61B17/00 ,  A61B17/16 ,  A61C1/00 ,  A61C3/02 ,  A61C8/00 ,  A61C19/04 ,  A61C5/00

CPC classification number: B23Q17/0985 ,  A61B17/16 ,  A61B2017/00084 ,  A61C1/00 ,  A61C8/0089 ,  A61C19/04 ,  Y10T408/05 ,  Y10T408/21

Abstract: This invention is a temperature gauge (30) for surgical drills (15) of the type having a surgical head (18) to which a drill bur (20) having a throughbore extending to its drill bur tip is removably mounted, and includes a temperature sensor (36) receivable in the drill bur throughbore for sensing and measuring the temperature at the drill bur tip and a thermometer (31) coupled to the temperature sensor (36) for displaying the temperature at the drill bur tip. A method of measuring the temperature of the drill site in the bone of a patient is also disclosed.