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公开(公告)号：EP3914692A1
公开(公告)日：2021-12-01
申请号：EP20743955.5
申请日：2020-01-24
发明人： HUBER, Thomas , VAN RAAD, Damian
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公开(公告)号：EP3622271A1
公开(公告)日：2020-03-18
申请号：EP18798715.1
申请日：2018-05-11
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公开(公告)号：EP2217133B1
公开(公告)日：2017-12-20
申请号：EP08847577.7
申请日：2008-11-07
IPC分类号： A61B3/024 , A61B5/0484
CPC分类号： A61B3/024 , A61B5/04842
摘要： A method for assessing the function of at least one sensory field of a subject, and apparatus and systems for carrying out the method, the method comprising: using a display, presenting stimuli to selected locations of the sensory field, the selected locations being centred at points on a sampling grid spanning a portion of the sensory field, wherein the individual stimuli if presented simultaneously at the sampling grid points would overlap in the space defined by the sensory dimensions of the field; using a sensor, detecting responses in the subject's sensory field evoked by the stimuli; and processing the detected responses to relate them to the function of the subject's sensory field at the selected locations.
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公开(公告)号：EP3204427A1
公开(公告)日：2017-08-16
申请号：EP15848180.4
申请日：2015-10-09
CPC分类号： A61K39/0275 , A61K9/1271 , A61K39/00 , A61K39/12 , A61K39/295 , A61K2039/523 , A61K2039/55555 , A61K2039/572 , A61K2039/70 , C07K14/245 , C07K14/255 , C07K2319/00 , C07K2319/21 , C12N2740/16034 , Y02A50/476 , Y02A50/482
摘要： The present invention is directed generally to chimeric proteins that can facilitate targeting of nanoparticulate carriers to antigen presenting cells, and to nanoparticulate carriers comprising these chimeric proteins. The invention is also directed to methods of internalising an antigen in an antigen presenting cell, and methods of eliciting an immune response to an antigen in a subject, using the nanoparticulate carriers comprising the chimeric proteins.
摘要翻译： 本发明总体上涉及可以促进将纳米颗粒载体靶向抗原呈递细胞的嵌合蛋白质以及包含这些嵌合蛋白质的纳米颗粒载体。 嵌合蛋白的一个实施方案包含TLR5激动剂如鞭毛蛋白和gp120衍生的肽。 本发明还涉及抗原呈递细胞中抗原内化的方法，以及使用包含嵌合蛋白的纳米微粒载体在受试者中引发针对抗原的免疫应答的方法。
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公开(公告)号：EP3100100A1
公开(公告)日：2016-12-07
申请号：EP15743111.5
申请日：2015-01-30
发明人： LEE, Woei Ming
CPC分类号： B29D11/0048 , B29C64/106 , B29D11/00432 , B29K2083/00 , B29L2011/0016 , B33Y10/00 , B33Y70/00 , G02B1/041 , G02B3/0018 , C08L83/04
摘要： Disclosed is a lens fabrication method (100) which uses a droplet of polydimethylsiloxane (PDMS) solution (210) cured on a slide (214) to form a PDMS support layer (211 ) having a curved surface (211 a). Further PDMS droplet (210) is then deposited on the curved surface (211 a) of the PDMS support layer (211 ); the slide (214) is then inverted to allow gravitational force to pull the uncured, further PDMS solution (210) down. The further PDMS solution (210) on the inverted slide is then cured. Each repetition of depositing, slide-inverting, and curing of the further PDMS droplet (210) adds an additional layer of PDMS, altering the shape and focal-length of the lens.
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公开(公告)号：EP2734468A1
公开(公告)日：2014-05-28
申请号：EP12814402.9
申请日：2012-07-13
发明人： NOTLEY, Shannon
摘要： Disclosed herein is a method for exfoliating a laminar material to form an exfoliated material, in which the laminar material is ultrasonicated in a solution of a surfactant for sufficient time to form the exfoliated material. At all times during the ultrasonication the concentration of the surfactant in the solution is maintained sufficient to form a complete monolayer on the surfaces of the laminar material and the exfoliated material in the solution, or sufficient to sterically stabilize the laminar and exfoliated materials against aggregation.
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8.发明授权
公开(公告)号：EP1267703B1
公开(公告)日：2010-11-17
申请号：EP01916739.4
申请日：2001-03-27
IPC分类号： A61B3/00 , A61B5/00 , A61B5/0484
CPC分类号： A61B5/04842 , A61B5/4064
摘要： A method and an apparatus are described for simultaneously assessing the functional status of component parts of the nervous system by presenting sparse stimuli to one or more parts of the sensory nervous system. Sparse stimuli consist of temporal sequences of stimulus conditions presented against a baseline null stimulus condition, where the non-null stimulus condition, or conditions, are presented relatively infrequently. The low probability of encountering a stimulus differing from a baseline or null stimulus condition in sparse stimulus sequences insures that gain control mechanisms within the nervous system will increase the neural response magnitude and also bias the measured responses to those neurone populations having such gain controls. The consequently increased response amplitudes ensure more reliably recorded responses than are obtained with non-sparse stimuli.
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公开(公告)号：EP1900038A1
公开(公告)日：2008-03-19
申请号：EP06752613.7
申请日：2006-06-16
IPC分类号： H01L31/02
CPC分类号： H01L31/035281 , H01L31/042 , H01L31/0504 , H01L31/0508 , Y02E10/50
摘要： A solar cell interconnection process for forming a solar cell sub-module for a photovoltaic device, the process including the steps of mounting a plurality of elongate solar cells (101) on a crossbeam (102) on patches of solderable material (201) which is used to maintain solder in position, the elongate solar cells being in a substantially longitudinally parallel and generally co-planar configuration: and establishing one or more conductive pathways (204) extending between adjacent cells to electrically interconnect the elongate solar cells via the contacts (202, 203): wherein the one or more conductive pathways are established by wave soldering.
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10.发明授权A CELL AND METHOD FOR FORMING A COMPOSITE HARD MATERIAL AND COMPOSITE HARD MATERIALS FORMED THEREBY 有权CELL AND METHOD FOR形成硬复合材料和硬质复合材料
公开(公告)号：EP1051240B1
公开(公告)日：2007-10-10
申请号：EP98954061.2
申请日：1998-11-12
IPC分类号： B01J3/06 , C01B35/14 , C04B35/52 , C04B35/5831
CPC分类号： C04B35/645 , B01J3/06 , B01J2203/062 , B01J2203/0645 , B01J2203/0655 , B01J2203/066 , B32B18/00 , C04B35/52 , C04B35/5831 , C04B35/6316 , C04B2235/3826 , C04B2235/3873 , C04B2235/427 , C04B2235/428 , C04B2235/5436 , C04B2235/5472 , C04B2235/616 , C04B2235/6562 , C04B2235/666 , C04B2235/721 , C04B2235/728 , C04B2235/75 , C04B2235/77 , C04B2235/80 , C04B2235/94 , C04B2235/96 , C04B2237/083 , C04B2237/086 , C04B2237/341 , C04B2237/361 , C04B2237/363 , C04B2237/365 , C04B2237/368 , C04B2237/525
摘要： A cell for forming a composite hard material and hard materials and methods of forming composite hard materials are disclosed. A cell (10) in which the article is formed includes a talc outer sleeve (12), a glass sleeve (14) and a reflecting foil (22). A heater (18) is arranged inwardly of the foil (22) and a barrier layer (16) is arranged inwardly of the glass sleeve (14). A central column (20) is defined for receiving the charge of material (50) from which the hard composite material is to be formed. The charge material is located in a mould (76, 100) which can define the final shape of the article thereby avoiding the need for additional machining, and the mould and charge material are subject to high temperature and pressure to form the composite material whilst maintaining the charge subject to hydrostatic pressure during the application of pressure and high temperature and maintaining a low temperature gradient across the charge during formation of the composite hard material to reduce uneven pressurisation of the composite hard material. The article may also be formed by forming first and second mixtures (120, 130) of composite hard material so as to form an outer surface on the article which has a higher hard particle content than an interior core portion of the article.
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