专利检索 ap:"The United States of America, as Represented by the Secretary, Department of Health AND Human Services" 第 1 页

1.

发明公开
NIPAH HENIPAVIRUS VIRUS REPLICON PARTICLES AND THEIR USE 审中-公开

公开(公告)号：EP4460324A1

公开(公告)日：2024-11-13

申请号：EP22859506.2

申请日：2022-12-30

申请人： The United States of America, as represented by The Secretary, Department of Health and Human Services

发明人： WELCH, Stephen R. , LO, Michael K. , KAINULAINEN, Markus H. , SPENGLER, Jessica R. , SPIROPOULOU, Christina F. , NICHOL, Stuart T.

IPC分类号： A61K39/12 , A61P31/14 , C12N15/00

2.

发明公开
METHODS AND SYSTEMS FOR ANALYZING TARGET ENGAGEMENT DATA FROM BIOLOGICAL ASSAYS 审中-公开

公开(公告)号：EP4453236A1

公开(公告)日：2024-10-30

申请号：EP22854698.2

申请日：2022-12-21

申请人： The United States of America, as represented by the Secretary, Department of Health and Human Services

发明人： RONZETTI, Michael H. , HENDERSON, Mark J. , SANCHEZ, Tino W. , MICHAEL, Samuel G. , VOSS, Ty C. , BALJINNYAM, Bolormaa , SIMEONOV, Anton

IPC分类号： C12Q1/66 , G01N33/58 , G01N33/68 , G01N33/542

3.

发明公开
ANTI-MESOTHELIN POLYPEPTIDES, PROTEINS, AND CHIMERIC ANTIGEN RECEPTORS 审中-公开

公开(公告)号：EP4448566A1

公开(公告)日：2024-10-23

申请号：EP22854336.9

申请日：2022-12-16

申请人： The United States of America, as represented by the Secretary, Department of Health and Human Services

发明人： PASTAN, Ira H. , ONDA, Masanori , HO, Mitchell , LIU, Xiu-fen , BERA, Tapan , CHAKRABORTY, Anirban

IPC分类号： C07K16/18 , C07K16/30 , C07K14/825 , A61P35/00

4.

发明公开
CANNABINOID RECEPTOR MODULATING COMPOUNDS 审中-公开

公开(公告)号：EP4444701A1

公开(公告)日：2024-10-16

申请号：EP22847074.6

申请日：2022-12-08

申请人： The United States of America, as represented by The Secretary, Department of Health and Human Services

发明人： IYER, Malliga R. , KUNOS, George , CINAR, Resat

IPC分类号： C07D231/06 , C07D401/12 , C07D403/12 , C07D407/12 , A61P1/00 , A61P3/00 , A61P9/00 , A61P25/00 , A61P29/00 , A61P31/00 , A61P35/00 , A61K31/4155

5.

发明公开
PREFUSION RSV F PROTEINS AND THEIR USE 审中-公开

公开(公告)号：EP4421177A2

公开(公告)日：2024-08-28

申请号：EP24174501.7

申请日：2014-03-13

申请人： The United States of America, as represented by the Secretary, Department of Health and Human Services

发明人： BOYINGTON, Jeffrey , GEORGIEV, Ivelin, Stefanov , PANCERA, Marie , SOTO, Cinque , SRIVATSAN, Sanjay , STEWART-JONES, Guillaume , KWONG, Peter, D. , GRAHAM, Barney, S. , MCLELLAN, Jason, S. , JOYCE, Michael, Gordon , KANEKIYO, Masaru , ZHANG, Baoshan , CHEN, Lei , CHEN, Man , CHUANG, Gwo-Yu , GORMAN, Jason , YANG, Yongping , ZHOU, Tongqing , SASTRY, Mallika , OFEK, Gilad

IPC分类号： C12N15/62

CPC分类号： A61K39/155 , A61K2039/5320130101 , A61K2039/5556120130101 , A61K2039/5556620130101 , C12N2760/1853420130101 , A61K2039/525220130101 , A61K2039/525420130101 , A61K2039/54320130101 , A61K2039/5550520130101 , C12N2710/1034320130101 , A61K39/12 , C07K2319/2120130101 , C07K2319/2220130101 , C07K2319/5020130101 , C07K2319/7020130101 , C07K2319/73520130101 , C12N2760/1852220130101 , C07K14/005 , A61P31/14 , A61P43/00

摘要： Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject.

6.

发明公开
ANTI-CMPL DIVALENT SCFV AND USES THEREOF 审中-实审

公开(公告)号：EP4413042A1

公开(公告)日：2024-08-14

申请号：EP22813001.9

申请日：2022-09-30

申请人： The United States of America, as represented by The Secretary, Department of Health and Human Services

发明人： LAROCHELLE, Andre , ARAKI, Daisuke , MAGNANI, Diogo , WANG, Zhirui

IPC分类号： C07K16/28 , A61K47/68 , C12N5/0789 , C07K14/34

CPC分类号： C07K14/34 , C07K2319/5520130101 , C07K16/2866 , C07K2317/62220130101 , C07K2317/3520130101 , C07K2317/7320130101 , A61K2039/50520130101 , C07K2317/9420130101 , A61P37/06 , A61K47/65 , A61K47/6845 , A61K47/6829

7.

发明公开
SURGICAL TOOL FOR OCULAR TISSUE TRANSPLANTATION 审中-实审

公开(公告)号：EP4309635A3

公开(公告)日：2024-04-24

申请号：EP23215832.9

申请日：2015-07-10

申请人： The United States of America, as represented by the Secretary, Department of Health and Human Services

发明人： MAMINISHKIS, Arvydas

IPC分类号： A61F9/00 , A61F2/14 , A61F9/007

CPC分类号： A61F9/0008 , A61F9/007 , A61F9/013 , A61F2/142

摘要： Disclosed are devices and methods for delivering a sheet of tissue into the eye in such a way that damage to the tissue is minimized, damage to the eye during insertion and manipulation of the tissue is minimized, and the tissue is released and delivered in a precise and controlled fashion.