摘要:
The present invention provides SOCE inhibitors that are useful as therapeutic agents in a variety of applications. The present invention also relates to pharmaceutical compositions, products and kits comprising such SOCE inhibitors, and methods of using the SOCE inhibitors in the treatment of a variety of diseases.
摘要:
The invention relates to an electromagnetic system for exploring the seabed in a marine environment, comprising a current injection module comprising two electrodes (6) spaced apart from one another, said injection electrodes being capable of injecting a current at a predetermined voltage into the marine environment close to the seabed, said injection electrodes having a contact surface with the marine environment, a data acquisition module comprising at least two measuring sensors for measuring electrical or magnetic data at at least two points of the marine environment close to the seabed, and a power supply module for supplying power to the current injection module. According to the invention, each electrode comprises one or more separate conductive elements that are electrically connected to each other and arranged in such a way as to form a conductive network or a multilayer conductive assembly having a large contact surface with the marine environment.
摘要:
The invention relates to the use of the fraction of the STIM1 protein localized to the plasma membrane of the cells in a method for screening candidate molecules for treating chronic lymphatic leukaemia and/or systemic lupus erythematosus. The invention also relates to a substance interacting with the fraction of the STIM1 protein localized to the plasma membrane of the cells for use as a medicinal product in the treatment of chronic lymphatic leukaemia and/or systemic lupus erythematosus, as well as to a pharmaceutical composition comprising at least one substance according to the invention.