摘要:
The present invention relates to methods for restoring the function of a mutated dysferlin comprising the step of preventing splicing of one or more exons which encode amino acid sequences that cause said dysferlin dysfunction. Particularly, the splicing of exon 32 is prevented. The present invention also relates to a method for treating a dysferlinopathy in a patient in need thereof, comprising the step of administering to said patient antisense oligonucleotides complementary to nucleic acid sequences that are necessary for correct splicing of one or more exons which encode amino acid sequences that cause said dysfunction. Particularly, the splicing of exon 32 is prevented.
摘要:
The present invention relates to a method for producing hydrogen (H 2 ) comprising the steps consisting in : a) reacting a compound (C) comprising one or more groups Si-H with a fluoride ions source, thereby forming hydrogen and a by-product (C1); and b) recovering the obtained hydrogen.
摘要:
The invention relates to a method for diagnosis of and following in vitro of the condition of the vaginal flora with regard to the presence of a bacterial vaginosis and where necessary following the therapeutic treatment thereof, characterised in that the presence of a bacterial vaginosis or failure of the current therapeutic treatment is determined when the concentrations of specific sequences present in a single copy of the DNA of the bacteria Atopobium vaginae and Gardnerella vaginalis, in the DNA extract of the vaginal secretion of a patient are such that at least the following two conditions a) and b) are met: a) the concentration Ca of said DNA fragment from Atopobium vaginae is greater than or equal to 108 copies/ml and b) the concentration Cg in said DNA fragment from Gardnerella vaginalis is greater than or equal to 109 copies/ml.
摘要:
The invention aims at a hybrid nanocomposite material comprising electrically conducting inorganic elongated nanocrystals grafted on at least part of the surface thereof with an electrically conducting organic compound, and a preparation process thereof. The invention further discloses thin films, solar cells and switchable devices comprising said hybrid nanocomposite.
摘要:
The invention concerns the use of an antigen containing protein A and in particular of Staphylococcus aureus as non-specific antigen introduced in bacterial serology reactions as positive control of the introduction of the serum to be tested.
摘要:
The invention relates to the technical fields of biology, pharmacology and medicine and the inventive compositions are suitable for use, for example, in the human and animal health fields. More specifically, the invention relates to the use of a cAMP modulator in the preparation of compositions that are intended for the prevention or treatment of peripheral neuropathies. The invention further relates to tools and kits used to prepare the aforementioned compositions.
摘要:
L'invention concerne un procédé de surveillance épidémiologique mis en oeuvre à l'aide d'une communauté de services réseau déployée au sein de plusieurs serveurs [1,2,3] aptes à communiquer entre eux et dont au moins un d'entre eux, dit serveur de données [1], met en oeuvre un service réseau de stockage [10] de données épidémiologiques en provenance d'au moins un système de déclaration [5',6] de données épidémiologiques, ladite communauté pouvant être utilisée par plusieurs clients réseau [5,5'] dont au moins un client dit de surveillance [5].