摘要:
The invention relates to substances with antibiotic activity and methods to treat infections. The invention provides a method to prevent or hamper division or proliferation of a prokaryotic cell or organism comprising inhibiting polymerisation and/or depolymerisation of cell-division protein FtsZ or analogue thereof by contacting said protein with a guanoside triphosphate (GTP) analogue capable of binding to said protein.
摘要:
The invention relates to a method for imaging an object, comprising the illumination of the object, and the detection of light coming from an area where the object is located and, based on the detected light, forming the image, with the illumination of the object taking place by distinguishing image elements in an imaging plane or space, and by separately illuminating the object parts corresponding with these image elements, while simultaneously registering the applied illumination dose of these object parts, and wherein the image is subsequently constructed by assembling the image elements corresponding with the illuminated object parts, subject to the light output and illumination doses pertaining to those image elements, wherein the illumination dose of each separate object part depends at least on a light output and/or illumination dose of another object part or several other object parts.
摘要:
A method for measuring a parameter of a substrate, comprises receiving pump radiation. A metrology target on the substrate is irradiated with the received radiation, thereby generating, through resonances, harmonic generated radiation. Using a metrology sensor, intensities are detected of at least two opposite radiation orders of the harmonic generated radiation diffracted by the metrology target. The parameter of the substrate is determined based on the intensities of the at least two opposite radiation orders and a peak wavelength of the harmonic generated radiation.
摘要:
An EUV radiation source comprising a fuel emitter configured to produce fuel droplets; a laser system configured to illuminate a fuel droplet at a plasma formation region, the laser system comprising: a first laser configured to produce radiation of a first wavelength in a first radiation beam, a second laser configured to produce radiation of a second wavelength in a second radiation beam, and a first parametric amplifier arranged to receive the radiation of the first wavelength and radiation of the second wavelength and generate an amplified radiation beam; and a beam delivery system for delivering the amplified radiation beam to the plasma formation region.
摘要:
The invention provides a method for recognition of information in digital image data, said method comprising a learning phase on a data set of example digital images having known information, and characteristics of categories are computed automatically from each example digital image and compared to its known category, said method comprises training a convolutional neural network comprising network parameters using said data set, in which via deep learning each layer of said convolutional neural network is represented by a linear decomposition of all filters as learned in each layer into basis functions.
摘要:
The invention provides methods for increasing the replicative life span and/or stability of an antibody producing cell, comprising - providing said antibody producing cell with a compound capable of directly or indirectly enhancing BCL6 expression and/or culturing said antibody producing cell in the presence of a compound capable of directly or indirectly enhancing BCL6 expression; and - directly or indirectly increasing the amount of Bcl-xL or another anti-apoptotic gene expression product within said antibody producing cell. Stable antibody producing cells and cell lines are also provided, as well as methods for producing antibodies using such cells and/or cell lines.
摘要:
A method to adjust or tune mechanical settings of a mammography apparatus comprising an x-ray source, a paddle and a detector with a detector cover, wherein before executing an x-ray measurement a patient's breast is placed and compressed between the detector cover and the paddle, wherein prior to the x-ray measurement reaction forces between the mammography apparatus and the patient's breast are minimized. The invention relates further to a mammography apparatus comprising an x-ray source, a paddle and a detector with a detector cover, which apparatus is provided with at least one weighing means to measure the downwards forces exerted by (the part of) the apparatus above the weighing means towards the ground.
摘要:
A composite material comprising 10-98 wt. % of a bio-based particulate or fibrous filler and at least 2 wt. % of a polyester derived from an aliphatic polyalcohol with 2-15 carbon atoms and a polyacid, wherein the polyacid comprises at least 10 wt. % of tricarboxylic acid. Preferably, the filler is in the form of particles, fibers, and/or random or non-random layers. A plant-based filler may be used, in particular a cellulosic or lignocellulosic material, more in particular one or more materials selected from wood chips, wood flakes, sawdust, pulp, e.g., pulp of (recycled) paper or other fiber pulp, and plant-derived fibers such as cotton, linen, flax, and hemp. An animal-derived filler, in particular an animal-derived fiber such as wool, hair, silk, or feathers may also be used. Preferably the polyalcohol is selected from one or more of glycerol, sorbitol, xylitol, mannitol, 1,2-propane diol, 1,3-propane diol, and 1,2-ethane diol, in particular glycerol. The polyacid preferably is an aliphatic diacid or triacid with 3-15 carbon atoms. Examples of suitable acids include citric acid, succinic acid, and itaconic acid. The composite material according to the invention has fire-retardant properties, which makes it particularly suitable for applications where fire-retardancy is an issue.
摘要:
The invention pertains to a method for reduction of the cyanide content of a metals-containing wastewater fraction by contacting a wastewater fraction comprising cyanide compounds and metal compounds, with a metals content of at least 100 ppm, with hydrogen peroxide and a solid catalyst comprising at least 50 wt.% of a copper salt with a solubility of less than 10 exp(-5) mol/liter (in water at 20°C, 1 atm). It has been found that when a solid catalyst comprising at least 50 wt.% of a copper salt with a solubility of less than 10 exp(-5) mol/liter (in water at 20°C, 1 atm) is used in combination with hydrogen peroxide in the reduction of the cyanide content of a cyanide compound-containing wastewater fraction having a metal compound content of at least 100 ppm, a method is obtained which shows an efficient removal of cyanide compounds from a difficult to treat fraction.