公开(公告)号：EP3559265A2

公开(公告)日：2019-10-30

申请号：EP17885003.8

申请日：2017-12-22

申请人： 10X Genomics, Inc.

发明人： BELGRADER, Phillip ,  BENT, Zachary ,  GOPALAN, Vijay Kumar Sreenivasa ,  HARADA, Josephine ,  HINDSON, Christopher ,  LENJI, Mohammad Rahimi ,  MCDERMOTT, Geoffrey ,  MEER, Elliott ,  MIKKELSEN, Tarjei Sigurd ,  O'KEEFFE, Christopher Joachim ,  PFEIFFER, Katherine ,  PRICE, Andrew D. ,  RYVKIN, Paul ,  SAXONOV, Serge ,  STUELPNAGEL, John R. ,  TERRY, Jessica Michele

IPC分类号： C12Q1/68 ,  C12Q1/6811 ,  C12Q1/6806 ,  C12Q1/6869 ,  C12Q1/6874 ,  C12Q1/6886 ,  C12Q1/6883 ,  C12P19/34 ,  C12N15/10

公开(公告)号：EP3896171A1

公开(公告)日：2021-10-20

申请号：EP21169849.3

申请日：2017-12-22

申请人： 10X Genomics, Inc.

发明人： BELGRADER, Phillip ,  BENT, Zachary ,  GOPALAN, Vijay Kumar Sreenivasa ,  HARADA, Josephine ,  HINDSON, Christopher ,  LENJI, Mohammad Rahimi ,  MCDERMOTT, Geoffrey ,  MEER, Elliott ,  MIKKELSEN, Tarjei Sigurd ,  O'KEEFFE, Christopher Joachim ,  PFEIFFER, Katherine ,  PRICE, Andrew D. ,  RYVKIN, Paul ,  SAXONOV, Serge ,  STUELPNAGEL, John R. ,  TERRY, Jessica Michele

IPC分类号： C12Q1/6804 ,  C12N15/10 ,  C12Q1/6806

摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for tagging analytes for characterization.

公开(公告)号：EP3978622A1

公开(公告)日：2022-04-06

申请号：EP21194770.0

申请日：2017-12-22

申请人： 10X Genomics, Inc.

发明人： BELGRADER, Phillip ,  BENT, Zachary ,  GOPALAN, Vijay Kumar Sreenivasa ,  HARADA, Josephine ,  HINDSON, Christopher ,  LENJI, Mohammad Rahimi ,  MCDERMOTT, Geoffrey ,  MEER, Elliott ,  MIKKELSEN, Tarjei Sigurd ,  O'KEEFFE, Christopher Joachim ,  PFEIFFER, Katherine ,  PRICE, Andrew D. ,  RYVKIN, Paul ,  SAXONOV, Serge ,  STUELPNAGEL, John R. ,  TERRY, Jessica Michele

IPC分类号： C12Q1/6804 ,  C12N15/10 ,  C12Q1/6806

摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for tagging analytes for characterization.

公开(公告)号：EP4043582A1

公开(公告)日：2022-08-17

申请号：EP22158749.6

申请日：2017-12-22

申请人： 10X Genomics, Inc.

发明人： BELGRADER, Phillip ,  BENT, Zachary ,  GOPALAN, Vijay Kumar Sreenivasa ,  HARADA, Josephine ,  HINDSON, Christopher ,  LENJI, Mohammad Rahimi ,  MCDERMOTT, Geoffrey ,  MEER, Elliott ,  MIKKELSEN, Tarjei Sigurd ,  O'KEEFFE, Christopher Joachim ,  PFEIFFER, Katherine ,  PRICE, Andrew D ,  RYVKIN, Paul ,  SAXONOV, Serge ,  STUELPNAGEL, John R. ,  TERRY, Jessica Michele

IPC分类号： C12Q1/6804 ,  C12N15/10 ,  C12Q1/6806

摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for tagging analytes for characterization.

公开(公告)号：EP3913067A1

公开(公告)日：2021-11-24

申请号：EP21175267.0

申请日：2017-12-22

申请人： 10X Genomics, Inc.

发明人： BELGRADER, Phillip ,  BENT, Zachary ,  GOPALAN, Vijay Kumar Sreenivasa ,  HARADA, Josephine ,  HINDSON, Christopher ,  LENJI, Mohammad Rahimi ,  MCDERMOTT, Geoffrey ,  MEER, Elliott ,  MIKKELSEN, Tarjei Sigurd ,  O'KEEFFE, Christopher Joachim ,  PFEIFFER, Katherine ,  PRICE, Andrew D. ,  RYVKIN, Paul ,  SAXONOV, Serge ,  STUELPNAGEL, John R. ,  TERRY, Jessica Michele

IPC分类号： C12Q1/6804 ,  C12N15/10 ,  C12Q1/6806

摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for tagging analytes for characterization.