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公开(公告)号：EP3700672A1
公开(公告)日：2020-09-02
申请号：EP18801153.0
申请日：2018-10-24
申请人： 10X Genomics, Inc.
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公开(公告)号：EP4375376A3
公开(公告)日：2024-08-14
申请号：EP24167618.8
申请日：2018-04-26
申请人： 10X Genomics, Inc.
发明人： LEE, Josephine , MARRS, Samuel , MCDERMOTT, Geoffrey , MESCHI, Francesca , MONTESCLAROS, Luz , PFEIFFER, Katherine , SHUGA, Joseph Francis , TERRY, Jessica Michele , ZIRALDO, Solongo B.
IPC分类号： C12N9/12 , C12N9/22 , C12N15/33 , C12Q1/6806 , C12Q1/6869
CPC分类号： C12N9/1276 , C12Y207/07049 , C07K2319/2120130101 , C07K2319/5020130101 , C12Q1/6869 , C12Q1/6806
摘要： Disclosed herein, are compositions, methods, and kits comprising engineered reverse transcription enzymes that exhibit several desired properties such as thermal stability, processive reverse transcription, non-templated base addition, and template switching ability. The engineered reverse transcription enzymes described herein demonstrate unexpectedly higher resistance to cell lysate inhibition, greater ability to capture full-length mRNA transcripts, and demonstrate improved results in small reaction volumes as compared to other engineered reverse transcription enzymes.
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公开(公告)号：EP4241882A3
公开(公告)日：2023-12-06
申请号：EP22216643.1
申请日：2018-10-24
申请人： 10X Genomics, Inc.
发明人： BELHOCINE, Kamila , LEE, Josephine , MESCHI, Francesca , MONTESCLAROS, Luz , PFEIFFER, Katherine , PRICE, Andrew D. , SAPIDA, Jerald , SUKOVICH, David , WHEELER, Tobias Daniel , YIN, Yifeng
摘要： The present disclosure provides methods and systems for sample preparation and/or analysis. Samples may be cells, or may be derived from one or more cells. Sample preparation may comprise conducting one or more reactions on a target. Such reactions may be conducted in one or more partitions. One or more reactions may be performed in one or more successive operations.
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公开(公告)号：EP4375376A2
公开(公告)日：2024-05-29
申请号：EP24167618.8
申请日：2018-04-26
申请人： 10X Genomics, Inc.
发明人： LEE, Josephine , MARRS, Samuel , MCDERMOTT, Geoffrey , MESCHI, Francesca , MONTESCLAROS, Luz , PFEIFFER, Katherine , SHUGA, Joseph Francis , TERRY, Jessica Michele , ZIRALDO, Solongo B.
IPC分类号： C12N15/33
CPC分类号： C12N9/1276 , C12Y207/07049 , C07K2319/2120130101 , C07K2319/5020130101
摘要： Disclosed herein, are compositions, methods, and kits comprising engineered reverse transcription enzymes that exhibit several desired properties such as thermal stability, processive reverse transcription, non-templated base addition, and template switching ability. The engineered reverse transcription enzymes described herein demonstrate unexpectedly higher resistance to cell lysate inhibition, greater ability to capture full-length mRNA transcripts, and demonstrate improved results in small reaction volumes as compared to other engineered reverse transcription enzymes.
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公开(公告)号：EP4241882A2
公开(公告)日：2023-09-13
申请号：EP22216643.1
申请日：2018-10-24
申请人： 10X Genomics, Inc.
发明人： BELHOCINE, Kamila , LEE, Josephine , MESCHI, Francesca , MONTESCLAROS, Luz , PFEIFFER, Katherine , PRICE, Andrew D. , SAPIDA, Jerald , SUKOVICH, David , WHEELER, Tobias Daniel , YIN, Yifeng
摘要： The present disclosure provides methods and systems for sample preparation and/or analysis. Samples may be cells, or may be derived from one or more cells. Sample preparation may comprise conducting one or more reactions on a target. Such reactions may be conducted in one or more partitions. One or more reactions may be performed in one or more successive operations.
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公开(公告)号：EP3830289A1
公开(公告)日：2021-06-09
申请号：EP19755475.1
申请日：2019-08-02
申请人： 10X Genomics, Inc.
发明人： BELL, Jason , LEE, Josephine , NEMEC, Corey , MESCHI, Francesca
IPC分类号： C12Q1/6806
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公开(公告)号：EP3592847A1
公开(公告)日：2020-01-15
申请号：EP18791768.7
申请日：2018-04-26
申请人： 10X Genomics, Inc.
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