SOLID SUPPORT WITH A GRAFTED CHAIN
    6.
    发明公开
    SOLID SUPPORT WITH A GRAFTED CHAIN 审中-公开
    FESTERTRÄGERMIT AUFGEPROPFTER KETTE

    公开(公告)号:EP2296807A2

    公开(公告)日:2011-03-23

    申请号:EP09770606.3

    申请日:2009-05-11

    摘要: Articles that contain a solid support with a grafted chain extending from the solid support, methods of making these articles, and various uses of the articles are described. More specifically, the grafted chain has a functional group that can react with or interact with target compound. Alternatively, the functional group on the grafted chain can react with a modifying agent to provide another group that can react with or interact with the target compound. The grafted chains are attached to the solid support through a ring-opened azlactone group. The articles can be used to purify the target compound or to separate the target compound from other molecules in a sample.

    摘要翻译: 描述了含有从固体支持物延伸的接枝链的固体支持物的制品,制造这些制品的方法以及制品的各种用途。 更具体地,接枝链具有可与目标化合物反应或与其相互作用的官能团。 或者,接枝链上的官能团可以与改性剂反应,以提供可与目标化合物反应或与目标化合物相互作用的另一个基团。 接枝的链通过开环的吖内酯基团连接到固体支持物上。 该制品可用于纯化目标化合物或将目标化合物与样品中的其它分子分离。