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公开(公告)号：EP1979348A2
公开(公告)日：2008-10-15
申请号：EP06848055.7
申请日：2006-12-20
申请人： ABBOTT LABORATORIES
发明人： BETEBENNER, David, A. , DEGOEY, David, A. , MARING, Clarence, J. , KRUEGER, Allan, C. , IWASAKI, Nobuhiko , ROCKWAY, Todd, W. , COOPER, Curt, S. , ANDERSON, David, D. , DONNER, Pamela, L. , GREEN, Brian, E. , KEMPF, Dale, J. , LIU, Dachun , MCDANIEL, Keith,F. , MADIGAN, Darold, L. , MOTTER, Christopher, E. , PRATT, John, K. , SHANLEY, Jason, P. , TUFANO, Michael, D. , WAGNER, Rolf , ZHANG, Rong , MOLLA, Akhteruzzaman , MO, Hongmei , PILOT-MATIAS, Tami, J. , MASSE, Sherie, VL. , CARRICK, Robert, J. , HE, Weping , LU, Liangjun , GRAMPOVNIK, David, J.
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , C07D495/04 , C07D513/04
摘要： Compounds effective in inhibiting replication of Hepatitis C virus ('HCV') or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
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公开(公告)号：EP2367823A1
公开(公告)日：2011-09-28
申请号：EP09795662.7
申请日：2009-12-22
申请人： Abbott Laboratories
发明人： DEGOEY, David, A. , DONNER, Pamela, L. , KATI, Warren, M. , HUTCHINS, Charles, W. , KRUEGER, Allan, C. , RANDOLPH, John, T. , MOTTER, Christopher, E. , KRISHNAN, Preethi , MISTRY, Neeta, C. , PILOT-MATIAS, Tami, J. , PATEL, Sachin, V. , LI, Xiaoyan , SOLTWEDEL, Todd, N. , NELSON, Lissa, T.
IPC分类号： C07D471/04 , A61K31/4375 , A61K31/519 , A61P31/14
CPC分类号： C07D471/04 , C07D239/48
摘要： Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
摘要翻译： 描述了有效抑制丙型肝炎病毒（“HCV”）复制的化合物。 本发明还涉及制备这些化合物的方法，包含这些化合物的组合物，以及使用这些化合物治疗HCV感染的方法。
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公开(公告)号：EP2203431B1
公开(公告)日：2011-08-10
申请号：EP08832330.8
申请日：2008-09-17
申请人： Abbott Laboratories
发明人： FLENTGE, Charles, A. , HUTCHINSON, Douglas, K. , BETEBENNER, David, A. , DEGOEY, David, A. , DONNER, Pamela, L. , KATI, Warren, M. , KRUEGER, Allan, C. , LIU, Dachun , LIU, Yaya , LONGENECKER, Kenton, L. , MARING, Clarence, J. , MOTTER, Christopher, E. , PRATT, John, K. , RANDOLPH, John, T. , ROCKWAY, Todd, W. , STEWART, Kent, D. , WAGNER, Rolf , BARNES, David, M. , CHEN, Shuang , FRANCZYK, Thaddeus, S., II , GAO, Yi , HAIGHT, Anthony, R. , HENGEVELD, John, E. , KOTECKI, Brian, J. , LOU, Xiaochun , ZHANG, Geoff, G., Z.
IPC分类号： C07D239/22 , C07D239/54 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , A61K31/513 , A61P31/12
CPC分类号： C07D239/54 , A61K31/513 , A61K45/06 , C07D239/22 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , A61K2300/00
摘要： This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.
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公开(公告)号：EP2419404A1
公开(公告)日：2012-02-22
申请号：EP10714787.8
申请日：2010-04-14
申请人： Abbott Laboratories
发明人： DEGOEY, David, A. , HUTCHINS, Charles, W. , KATI, Warren, M. , DONNER, Pamela, L. , NELSON, Lissa, T. , JINKERSON, Tammie, K. , KEDDY, Ryan, G. , MOTTER, Christopher, E. , MATULENKO, Mark, A. , KRUEGER, Allan, C. , PATEL, Sachin, V. , RANDOLPH, John, T. , SOLTWEDEL, Todd, N.
IPC分类号： C07D205/02 , C07D207/16 , C07D209/52 , C07D401/12 , C07D403/04 , C07D403/12 , C07D413/12 , C07D417/12 , A61K31/454 , A61P29/00
CPC分类号： C07D207/16 , A61K31/4025 , A61K31/4184 , A61K31/454 , A61K31/5377 , A61K38/00 , C07D205/04 , C07D207/22 , C07D209/52 , C07D211/60 , C07D263/06 , C07D277/06 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07K5/06034 , C07K5/06043 , C07K5/0606 , C07K5/06069 , C07K5/06078 , C07K5/06139
摘要： Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
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公开(公告)号：EP1979348B1
公开(公告)日：2012-01-18
申请号：EP06848055.7
申请日：2006-12-20
申请人： ABBOTT LABORATORIES
发明人： BETEBENNER, David, A. , DEGOEY, David, A. , MARING, Clarence, J. , KRUEGER, Allan, C. , IWASAKI, Nobuhiko , ROCKWAY, Todd, W. , COOPER, Curt, S. , ANDERSON, David, D. , DONNER, Pamela, L. , GREEN, Brian, E. , KEMPF, Dale, J. , LIU, Dachun , MCDANIEL, Keith,F. , MADIGAN, Darold, L. , MOTTER, Christopher, E. , PRATT, John, K. , SHANLEY, Jason, P. , TUFANO, Michael, D. , WAGNER, Rolf , ZHANG, Rong , MOLLA, Akhteruzzaman , MO, Hongmei , PILOT-MATIAS, Tami, J. , MASSE, Sherie, VL. , CARRICK, Robert, J. , HE, Weping , LU, Liangjun , GRAMPOVNIK, David, J.
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , C07D495/04 , C07D513/04
摘要： Compounds effective in inhibiting replication of Hepatitis C virus ('HCV') or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
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公开(公告)号：EP2203431A1
公开(公告)日：2010-07-07
申请号：EP08832330.8
申请日：2008-09-17
申请人： Abbott Laboratories
发明人： FLENTGE, Charles, A. , HUTCHINSON, Douglas, K. , BETEBENNER, David, A. , DEGOEY, David, A. , DONNER, Pamela, L. , KATI, Warren, M. , KRUEGER, Allan, C. , LIU, Dachun , LIU, Yaya , LONGENECKER, Kenton, L. , MARING, Clarence, J. , MOTTER, Christopher, E. , PRATT, John, K. , RANDOLPH, John, T. , ROCKWAY, Todd, W. , STEWART, Kent, D. , WAGNER, Rolf , BARNES, David, M. , CHEN, Shuang , FRANCZYK, Thaddeus, S., II , GAO, Yi , HAIGHT, Anthony, R. , HENGEVELD, John, E. , KOTECKI, Brian, J. , LOU, Xiaochun , ZHANG, Geoff, G., Z.
IPC分类号： C07D239/22 , C07D239/54 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , A61K31/513 , A61P31/12
CPC分类号： C07D239/54 , A61K31/513 , A61K45/06 , C07D239/22 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , A61K2300/00
摘要： This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.
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