-
公开(公告)号：EP0882024B1
公开(公告)日：2002-02-06
申请号：EP96944941.2
申请日：1996-12-06
申请人： Abbott Laboratories
发明人： SHAM, Hing, Leung , NORBECK, Daniel, W. , CHEN, Xiaoqi , BETEBENNER, David, A. , KEMPF, Dale, J. , HERRIN, Thomas, R. , KUMAR, Gondi, N. , CONDON, Stephen, L. , COOPER, Arthur, J. , DICKMAN, Daniel, A. , HANNICK, Steven, M. , KOLACZKOWSKI, Lawrence , OLIVER, Patricia, A. , PLATA, Daniel, J. , STENGEL, Peter, J. , STONER, Eric, J. , TIEN, Jieh-Heh, J. , LIU, Jih-Hua , PATEL, Ketan, M.
IPC分类号： C07D239/10 , C07D239/22 , C07D207/26 , C07D241/08 , C07D263/22 , C07D233/32 , C07D207/40 , A61K31/415
CPC分类号： C07D207/27 , C07D207/404 , C07D207/408 , C07D223/10 , C07D233/32 , C07D233/42 , C07D239/10 , C07D239/22 , C07D241/08 , C07D241/18 , C07D253/06 , C07D263/22 , C07D307/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/12 , C07D409/14 , C07D417/12
-
公开(公告)号：EP2411352A2
公开(公告)日：2012-02-01
申请号：EP10722455.2
申请日：2010-03-25
申请人： Abbott Laboratories
发明人： BETEBENNER, David, A. , PRATT, John, K. , DEGOEY, David, A. , DONNER, Pamela, L. , FLENTGE, Charles, A. , HUTCHINSON, Douglas, K. , KATI, Warren, M. , KRUEGER, Allan, C. , LONGENECKER, Kenton, L. , MARING, Clarence, J. , RANDOLPH, John, T. , ROCKWAY, Todd, W. , TUFANO, Michael, D. , WAGNER, Rolf , LIU, Dachun
IPC分类号： C07C15/58 , C07D239/54 , C07D409/10 , C07D213/64 , C07D263/22 , C07D207/27 , C07D233/32 , C07D275/02 , A61P31/14 , C07D233/74 , C07D403/10 , A61K31/513 , C07D239/10 , C07D405/10 , A61K31/4412
CPC分类号： C07D409/10 , A61K31/18 , A61K31/27 , A61K31/402 , A61K31/4166 , A61K31/421 , A61K31/425 , A61K31/4418 , A61K31/503 , A61K31/513 , A61K45/06 , C07C311/08 , C07D207/27 , C07D213/64 , C07D233/32 , C07D233/72 , C07D239/10 , C07D239/54 , C07D263/22 , C07D263/24 , C07D275/02 , C07D403/10 , C07D405/10 , Y02P20/55
摘要： This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.
摘要翻译： 本发明涉及：（a）特别是抑制HCV的化合物及其盐; （b）可用于制备这些化合物和盐的中间体; （c）包含这些化合物和盐的组合物; （d）制备此类中间体，化合物，盐和组合物的方法; （e）使用这些化合物，盐和组合物的方法; 和（f）包含这些化合物，盐和组合物的试剂盒。
-
公开(公告)号：EP1979348A2
公开(公告)日：2008-10-15
申请号：EP06848055.7
申请日：2006-12-20
申请人： ABBOTT LABORATORIES
发明人： BETEBENNER, David, A. , DEGOEY, David, A. , MARING, Clarence, J. , KRUEGER, Allan, C. , IWASAKI, Nobuhiko , ROCKWAY, Todd, W. , COOPER, Curt, S. , ANDERSON, David, D. , DONNER, Pamela, L. , GREEN, Brian, E. , KEMPF, Dale, J. , LIU, Dachun , MCDANIEL, Keith,F. , MADIGAN, Darold, L. , MOTTER, Christopher, E. , PRATT, John, K. , SHANLEY, Jason, P. , TUFANO, Michael, D. , WAGNER, Rolf , ZHANG, Rong , MOLLA, Akhteruzzaman , MO, Hongmei , PILOT-MATIAS, Tami, J. , MASSE, Sherie, VL. , CARRICK, Robert, J. , HE, Weping , LU, Liangjun , GRAMPOVNIK, David, J.
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , C07D495/04 , C07D513/04
摘要： Compounds effective in inhibiting replication of Hepatitis C virus ('HCV') or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
-
公开(公告)号：EP2203431B1
公开(公告)日：2011-08-10
申请号：EP08832330.8
申请日：2008-09-17
申请人： Abbott Laboratories
发明人： FLENTGE, Charles, A. , HUTCHINSON, Douglas, K. , BETEBENNER, David, A. , DEGOEY, David, A. , DONNER, Pamela, L. , KATI, Warren, M. , KRUEGER, Allan, C. , LIU, Dachun , LIU, Yaya , LONGENECKER, Kenton, L. , MARING, Clarence, J. , MOTTER, Christopher, E. , PRATT, John, K. , RANDOLPH, John, T. , ROCKWAY, Todd, W. , STEWART, Kent, D. , WAGNER, Rolf , BARNES, David, M. , CHEN, Shuang , FRANCZYK, Thaddeus, S., II , GAO, Yi , HAIGHT, Anthony, R. , HENGEVELD, John, E. , KOTECKI, Brian, J. , LOU, Xiaochun , ZHANG, Geoff, G., Z.
IPC分类号： C07D239/22 , C07D239/54 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , A61K31/513 , A61P31/12
CPC分类号： C07D239/54 , A61K31/513 , A61K45/06 , C07D239/22 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , A61K2300/00
摘要： This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.
-
公开(公告)号：EP1560827B1
公开(公告)日：2010-12-29
申请号：EP03768559.1
申请日：2003-10-31
申请人： ABBOTT LABORATORIES
发明人： PRATT, John, K. , BETEBENNER, David, A. , DONNER, Pamela, L. , GREEN, Brian, E. , KEMPF, Dale, J. , MCDANIEL, Keith, F. , MARING, Clarence, J. , STOLL, Vincent, S. , ZHANG, Rong
IPC分类号： C07D471/04 , C07D513/04 , C07D519/00 , C07D495/04 , C07D417/04 , C07D513/14 , C07D417/14 , A61K31/554 , A61P31/00 , C07D215/22 , C07D401/04 , C07D213/69
CPC分类号： C07D213/69 , C07D215/22 , C07D401/04 , C07D417/04 , C07D417/14 , C07D471/04 , C07D495/04 , C07D513/04
摘要： The present invention provides an HCV polymerase inhibiting compound having the formula (I) and a composition comprising a therapeutically effective amount of said compound. The present invention also provides a method for inhibiting hepatitis C virus (HCV) polymerase, a method for inhibiting HCV viral replication, and a method for treating or preventing HCV infection. Processes for making said compounds, and synthetic intermediates employed in said processes, are also provided.
-
公开(公告)号：EP0882024A1
公开(公告)日：1998-12-09
申请号：EP96944941.0
申请日：1996-12-06
申请人： Abbott Laboratories
发明人： SHAM, Hing, Leung , NORBECK, Daniel, W. , CHEN, Xiaoqi , BETEBENNER, David, A. , KEMPF, Dale, J. , HERRIN, Thomas, R. , KUMAR, Gondi, N. , CONDON, Stephen, L. , COOPER, Arthur, J. , DICKMAN, Daniel, A. , HANNICK, Steven, M. , KOLACZKOWSKI, Lawrence , OLIVER, Patricia, A. , PLATA, Daniel, J. , STENGEL, Peter, J. , STONER, Eric, J. , TIEN, Jieh-Heh, J. , LIU, Jih-Hua , PATEL, Ketan, M.
IPC分类号： C07D , C07D253 , A61K31 , A61K38 , A61K45 , A61P31 , A61P43 , C07C231 , C07C235 , C07C273 , C07C275 , C07D207 , C07D211 , C07D223 , C07D233 , C07D239 , C07D241 , C07D243 , C07D263 , C07D265 , C07D267 , C07D277 , C07D279 , C07D281 , C07D401 , C07D403 , C07D405 , C07D409 , C07D413 , C07D417
CPC分类号： C07D207/27 , C07D207/404 , C07D207/408 , C07D223/10 , C07D233/32 , C07D233/42 , C07D239/10 , C07D239/22 , C07D241/08 , C07D241/18 , C07D253/06 , C07D263/22 , C07D307/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/12 , C07D409/14 , C07D417/12
摘要： A compound of formula (I) is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
-
公开(公告)号：EP1560827A1
公开(公告)日：2005-08-10
申请号：EP03768559.1
申请日：2003-10-31
申请人： Abbott Laboratories
发明人： PRATT, John, K. , BETEBENNER, David, A. , DONNER, Pamela, L. , GREEN, Brian, E. , KEMPF, Dale, J. , MCDANIEL, Keith, F. , MARING, Clarence, J. , STOLL, Vincent, S. , ZHANG, Rong
IPC分类号： C07D471/04 , C07D513/04 , C07D519/00 , C07D495/04 , C07D417/04 , C07D513/14 , C07D417/14 , A61K31/554 , A61P31/00 , C07D215/22 , C07D401/04 , C07D213/69
CPC分类号： C07D213/69 , C07D215/22 , C07D401/04 , C07D417/04 , C07D417/14 , C07D471/04 , C07D495/04 , C07D513/04
摘要： The present invention provides an HCV polymerase inhibiting compound having the formula (I) and a composition comprising a therapeutically effective amount of said compound. The present invention also provides a method for inhibiting hepatitis C virus (HCV) polymerase, a method for inhibiting HCV viral replication, and a method for treating or preventing HCV infection. Processes for making said compounds, and synthetic intermediates employed in said processes, are also provided.
-
公开(公告)号：EP1979348B1
公开(公告)日：2012-01-18
申请号：EP06848055.7
申请日：2006-12-20
申请人： ABBOTT LABORATORIES
发明人： BETEBENNER, David, A. , DEGOEY, David, A. , MARING, Clarence, J. , KRUEGER, Allan, C. , IWASAKI, Nobuhiko , ROCKWAY, Todd, W. , COOPER, Curt, S. , ANDERSON, David, D. , DONNER, Pamela, L. , GREEN, Brian, E. , KEMPF, Dale, J. , LIU, Dachun , MCDANIEL, Keith,F. , MADIGAN, Darold, L. , MOTTER, Christopher, E. , PRATT, John, K. , SHANLEY, Jason, P. , TUFANO, Michael, D. , WAGNER, Rolf , ZHANG, Rong , MOLLA, Akhteruzzaman , MO, Hongmei , PILOT-MATIAS, Tami, J. , MASSE, Sherie, VL. , CARRICK, Robert, J. , HE, Weping , LU, Liangjun , GRAMPOVNIK, David, J.
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , C07D495/04 , C07D513/04
摘要： Compounds effective in inhibiting replication of Hepatitis C virus ('HCV') or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
-
公开(公告)号：EP2203431A1
公开(公告)日：2010-07-07
申请号：EP08832330.8
申请日：2008-09-17
申请人： Abbott Laboratories
发明人： FLENTGE, Charles, A. , HUTCHINSON, Douglas, K. , BETEBENNER, David, A. , DEGOEY, David, A. , DONNER, Pamela, L. , KATI, Warren, M. , KRUEGER, Allan, C. , LIU, Dachun , LIU, Yaya , LONGENECKER, Kenton, L. , MARING, Clarence, J. , MOTTER, Christopher, E. , PRATT, John, K. , RANDOLPH, John, T. , ROCKWAY, Todd, W. , STEWART, Kent, D. , WAGNER, Rolf , BARNES, David, M. , CHEN, Shuang , FRANCZYK, Thaddeus, S., II , GAO, Yi , HAIGHT, Anthony, R. , HENGEVELD, John, E. , KOTECKI, Brian, J. , LOU, Xiaochun , ZHANG, Geoff, G., Z.
IPC分类号： C07D239/22 , C07D239/54 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , A61K31/513 , A61P31/12
CPC分类号： C07D239/54 , A61K31/513 , A61K45/06 , C07D239/22 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , A61K2300/00
摘要： This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.037 秒)
