公开(公告)号：EP1809733A4

公开(公告)日：2010-04-21

申请号：EP04794243

申请日：2004-10-06

申请人： AGENTASE LLC

发明人： LEJEUNE KEITH E ,  MYSLIWCZYK RICHARD J ,  HOLZAPFEL PAUL L ,  ERBELDINGER MARKUS

IPC分类号： C12M1/34 ,  C12Q1/34 ,  C12Q1/46

CPC分类号： G01N21/80 ,  C12Q1/001 ,  C12Q1/34 ,  C12Q1/37 ,  C12Q1/46 ,  G01N1/2035 ,  G01N1/2247 ,  G01N33/0031 ,  G01N33/0062 ,  G01N35/00871 ,  G01N35/1095

公开(公告)号：EP2069522A4

公开(公告)日：2010-06-09

申请号：EP07870735

申请日：2007-08-07

申请人： AGENTASE LLC

发明人： LEJEUNE KEITH E ,  BACIOR JENNIFER A ,  BERBERICH JASON A ,  ERBELDINGER MARKUS ,  LELE BHALCHANDRA SHRIPAD

IPC分类号： C12Q1/34 ,  C12M3/00 ,  C12Q1/68

CPC分类号： C12Q1/28 ,  C12Q1/34 ,  C12Q1/37 ,  C12Q1/46

公开(公告)号：EP1430142A4

公开(公告)日：2005-07-27

申请号：EP02731594

申请日：2002-05-02

申请人： AGENTASE LLC

发明人： LEJEUNE KEITH E ,  ERBELDINGER MARKUS

IPC分类号： C12Q1/00 ,  G01N33/543 ,  G01N33/94

CPC分类号： C12Q1/001 ,  G01N33/5438 ,  G01N33/94 ,  Y10S435/963

摘要： A sensor for detecting an analyte in an environment includes a first reaction system including a first enzyme and a substrate for the first enzyme. The analyte inhibits the reaction of the substrate catalyzed by the first enzyme. The sensor further includes at least a second reaction system that reacts to produce a first detectable state when the first enzyme is inhibited. In some embodiments, the reaction of the first reaction system can produce a second detectible state, different from the first detectible state. Another sensor for detecting an analyte in an environment includes a first reaction system including a first enzyme or a first substrate for the first enzyme. In this embodiment, the analyte is either a substrate for the first enzyme or the first enzyme if the first reaction system includes the first substrate. Figure (1) illustrates reaction schematics of one embodiment of a sensor of the present invention for detecting nerve agents.