公开(公告)号：EP0988302B1

公开(公告)日：2003-02-19

申请号：EP98930737.6

申请日：1998-05-27

申请人： ALTANA Pharma AG

发明人： SCHMIDT, Beate ,  ULRICH, Wolf-Rüdiger ,  AMSCHLER, Hermann ,  BEUME, Rolf ,  HÄFNER, Dietrich ,  BÄR, Thomas ,  MARTIN, Thomas ,  KILIAN, Ulrich ,  ELTZE, Manfrid ,  BRAND, Ursula ,  BOSS, Hildegard ,  KLEY, Hans-Peter ,  SCHUDT, Christian ,  GOEBEL, Karl-Josef ,  FLOCKERZI, Dieter ,  HATZELMANN, Armin

IPC分类号： C07D471/04 ,  A61K31/47

CPC分类号： C07D471/04

摘要： The invention concerns the compounds 8,9-Diethoxy-2-methyl-6- [4(p-toluenesulfonamido)phenyl] -1,2,3,4,4a,10b-hexahydrobenzo[c] [1,6]naphthyridine and 9-Ethoxy-8-methoxy-2- methyl-6-[4-(p-toluenesulfonamido) phenyl]-1,2,3,4,4a,10b-hexahydrobenzo [c][1,6]naphthyridine and their therapeutic application.