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公开(公告)号：EP1100483B1
公开(公告)日：2004-09-29
申请号：EP99938896.0
申请日：1999-07-30
申请人： Abbott Laboratories
IPC分类号： A61K31/136 , A61K31/137 , A61K31/167 , A61K31/4545 , A61K31/535 , A61K31/5375 , A61K31/5377 , A61K31/4025 , A61K31/222 , A61K31/40 , A61K31/45 , A61K31/24 , A61K31/341 , C07D295/06 , C07C219/06 , C07C211/52 , C07C215/16 , C07C271/28 , C07C219/10 , C07C217/76 , C07C323/29
CPC分类号： C07C211/52 , C07C211/50 , C07C215/16 , C07C217/76 , C07C217/80 , C07C219/06 , C07C229/18 , C07C233/43 , C07C233/44 , C07C233/62 , C07C233/80 , C07C271/28 , C07C311/39 , C07C323/29 , C07C2601/02 , C07D317/48
摘要： Compounds having Formula (I) are useful for modulating the glucocorticoid receptor in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of treating immune, autoimmune, inflammatory, adrenal imbalance, cognitive and behavioral diseases in a mammal.
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2.发明公开HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION 有权杂环醚和硫醚类化合物适用于控制化学突触传递
公开(公告)号：EP1047690A1
公开(公告)日：2000-11-02
申请号：EP98964167.5
申请日：1998-12-18
申请人： Abbott Laboratories
发明人： HOLLADAY, Mark, W. , ABREO, Melwyn, A. , GUNN, David, E. , LIN, Nan-Horng , GARVEY, David, S. , RYTHER, Keith , LEBOLD, Suzanne, A. , ELLIOTT, Richard, L. , HE, Yun , WASIAK, James, T. , BAI, Hao , DART, Michael, J. , EHRLICH, Paul, P. , LI, Yihong , KINCAID, John, F. , SCHKERYANTZ, Jeffrey, M. , LYNCH, John, K.
IPC分类号： C07D401/12 , C07D403/12 , C07D417/12 , C07D487/04 , C07D455/02 , A61K31/44 , A61K31/40 , A61K31/425 , A61K31/50 , A61K31/505 , A61K31/47
CPC分类号： C07D401/12 , C07D403/12 , C07D417/12 , C07D455/02 , C07D487/04
摘要： Novel compounds having formulas (I), (II) or (III) or pharmaceutically-acceptable salts or prodrugs thereof, which are useful for controlling synaptic transmission; to therapeutically-effective pharmaceutical compositions of these compounds; and to the use of said compositions to controlling synaptic transmission in human or veterinary patients.
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3.发明授权HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION 有权杂环醚和硫醚类化合物适用于控制化学突触传递
公开(公告)号：EP1047690B1
公开(公告)日：2004-03-24
申请号：EP98964167.5
申请日：1998-12-18
申请人： Abbott Laboratories
发明人： HOLLADAY, Mark, W. , ABREO, Melwyn, A. , GUNN, David, E. , LIN, Nan-Horng , GARVEY, David, S. , RYTHER, Keith , LEBOLD, Suzanne, A. , ELLIOTT, Richard, L. , HE, Yun , WASIAK, James, T. , BAI, Hao , DART, Michael, J. , EHRLICH, Paul, P. , LI, Yihong , KINCAID, John, F. , SCHKERYANTZ, Jeffrey, M. , LYNCH, John, K.
IPC分类号： C07D401/12 , C07D403/12 , C07D417/12 , C07D487/04 , C07D455/02 , A61K31/44 , A61K31/40 , A61K31/425 , A61K31/50 , A61K31/505 , A61K31/47
CPC分类号： C07D401/12 , C07D403/12 , C07D417/12 , C07D455/02 , C07D487/04
摘要： Novel compounds having formulas (I), (II) or (III) or pharmaceutically-acceptable salts or prodrugs thereof, which are useful for controlling synaptic transmission; to therapeutically-effective pharmaceutical compositions of these compounds; and to the use of said compositions to controlling synaptic transmission in human or veterinary patients.
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4.发明公开GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS 有权GLUCOCORTICOID SELEKTIVEENTZÜNDUNGSHEMMENDEMITTEL
公开(公告)号：EP1100483A2
公开(公告)日：2001-05-23
申请号：EP99938896.0
申请日：1999-07-30
申请人： Abbott Laboratories
IPC分类号： A61K31/136 , A61K31/137 , A61K31/167 , A61K31/4545 , A61K31/535 , A61K31/5375 , A61K31/5377 , A61K31/4025 , A61K31/222 , A61K31/40 , A61K31/45 , A61K31/24 , A61K31/341 , C07D295/06 , C07C219/06 , C07C211/52 , C07C215/16 , C07C271/28 , C07C219/10 , C07C217/76 , C07C323/29
CPC分类号： C07C211/52 , C07C211/50 , C07C215/16 , C07C217/76 , C07C217/80 , C07C219/06 , C07C229/18 , C07C233/43 , C07C233/44 , C07C233/62 , C07C233/80 , C07C271/28 , C07C311/39 , C07C323/29 , C07C2601/02 , C07D317/48
摘要： Compounds having Formula (I) are useful for modulating the glucocorticoid receptor in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of treating immune, autoimmune, inflammatory, adrenal imbalance, cognitive and behavioral diseases in a mammal.
摘要翻译： 具有式（I）的化合物可用于调节哺乳动物中的糖皮质激素受体。 还公开了包含式（I）的化合物的药物组合物和在哺乳动物中治疗免疫，自身免疫，炎性，肾上腺不平衡，认知和行为疾病的方法。
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