公开(公告)号：EP1366817A2

公开(公告)日：2003-12-03

申请号：EP03020294.9

申请日：1996-03-01

申请人： Alltech Associates, Inc.

发明人： Anderson, James M., Jr. ,  Saari-Nordhaus, Raaidah ,  Sims, Carl W. ,  Gerner, Yuri E.

IPC分类号： B01J39/06 ,  B01D15/08 ,  G01N30/52 ,  G01N30/96

CPC分类号： G01N27/453 ,  B01D15/361 ,  B01D15/3885 ,  B01J39/26 ,  G01N30/02 ,  G01N30/34 ,  G01N30/468 ,  G01N30/52 ,  G01N30/96 ,  G01N2030/285 ,  G01N2030/965 ,  G01N2030/0035 ,  B01D15/362

摘要： A system for generating a high purity eluant that can be used in detecting sample ions comprises: a water source, an eluant generating source, and a fluid flow path that is in fluid communication with the water source, wherein the fluid flow path is the only path for liquid flow through the eluant generating source. By electrolysis of water and combining electrolysis ions with counter ions of a sample a high-purity eluant is formed.

摘要翻译： 用于产生可用于检测样品离子的高纯度洗脱液的系统包括：水源，洗脱液生成源和与水源流体连通的流体流动路径，其中流体流动路径是唯一的 液体流过洗脱液生成源的路径。 通过电解电解和电解离子与样品的抗衡离子形成高纯度洗脱剂。

公开(公告)号：EP1099479B1

公开(公告)日：2003-09-10

申请号：EP01101801.7

申请日：1996-03-01

申请人： Alltech Associates, Inc.

发明人： Anderson, James M. Jr. ,  Saari-Nordhaus, Raaidah ,  Sims, Carl W. ,  Gerner, Yuri E.

IPC分类号： B01J39/06 ,  B01D15/08 ,  G01N30/96 ,  G01N30/52

CPC分类号： G01N27/453 ,  B01D15/361 ,  B01D15/3885 ,  B01J39/26 ,  G01N30/02 ,  G01N30/34 ,  G01N30/468 ,  G01N30/52 ,  G01N30/96 ,  G01N2030/285 ,  G01N2030/965 ,  G01N2030/0035 ,  B01D15/362

公开(公告)号：EP1048351A2

公开(公告)日：2000-11-02

申请号：EP00115245.3

申请日：1996-03-01

申请人： Alltech Associates, Inc.

发明人： Anderson, James M, Jr. ,  Saari-Nordhaus, Raaidah ,  Sims, Carl W. ,  Gerner, Yuri E.

IPC分类号： B01J39/06 ,  B01D15/08 ,  G01N30/52 ,  G01N30/96

CPC分类号： G01N27/453 ,  B01D15/361 ,  B01D15/3885 ,  B01J39/26 ,  G01N30/02 ,  G01N30/34 ,  G01N30/468 ,  G01N30/52 ,  G01N30/96 ,  G01N2030/285 ,  G01N2030/965 ,  G01N2030/0035 ,  B01D15/362

摘要： A system for generating a high purity eluant that can be used in detecting sample ions comprising: a path of fluid flow; a water source; an eluant generating source comprising a stationary phase in fluid communication with the path of fluid flow wherein at least a portion of the stationary phase is positioned between a first electrode and a second electrode; a power source in electrical communication with the first and second electrodes; an analytical column comprising ion exchange resin, the analytical column located downstream in the path of fluid flow from the eluant generating source; a suppressor comprising a suppressor stationary phase having exchangeable ions selected from the group consisting of hydronium ions and hydroxide ions, the suppressor being positioned downstream in the path of fluid flow from the analytical column, wherein at least portion of the suppressor stationary phase is positioned between a first suppressor electrode and a second suppressor electrode, the suppressor electrodes being in electrical communication with a power source; and a detector positioned downstream in the path of fluid flow from the suppressor.

摘要翻译： 一种用于产生可用于检测样品离子的高纯度洗脱液的系统，包括：流体流动路径; 水源; 洗脱液产生源，其包括与流体流动路径流体连通的固定相，其中所述固定相的至少一部分位于第一电极和第二电极之间; 与所述第一和第二电极电连通的电源; 分析柱，其包含离子交换树脂，分析柱位于来自洗脱液生成源的流体流动路径的下游; 抑制器，其包括具有选自由水合氢离子和氢氧根离子组成的组的可交换离子的抑制器固定相，所述抑制器位于从所述分析柱流动的流体路径的下游，其中所述抑制器固定相的至少一部分位于 第一抑制电极和第二抑制电极，所述抑制电极与电源电连通; 以及位于从抑制器流动的流体路径下游的检测器。

公开(公告)号：EP1640714A3

公开(公告)日：2006-07-05

申请号：EP05028383.7

申请日：2000-10-13

申请人： Alltech Associates, Inc.

发明人： Anderson, James M. Jr. ,  Saari-Nordhaus, Raaidah ,  Benedict, Bart C. ,  Sims, Carl W. ,  Gurner, Yuri ,  Pham, Hung Anthony

IPC分类号： G01N30/96

CPC分类号： G01N30/96 ,  B01D15/367 ,  G01N30/34 ,  G01N2001/4016 ,  G01N2030/965

摘要： A method of detecting analyte ions by continuous electrochemically suppressed ion chromatography comprising: (a) flowing analyte ions in an aqueous mobile phase comprising electrolyte through an analytical column separating means to form an aqueous chromatography effluent comprising separated analyte ions and electrolyte; (b) flowing the aqueous chromatography effluent through a suppressor means for splitting the chromatography effluent into a first chromatography effluent flow stream and a second chromatography effluent flow stream; (c) applying an electrical potential in the suppressor means such that electrolyte is electrochemically driven into the first chromatography effluent stream and away from the second chromatography effluent flow stream; (d) flowing the second chromatography effluent flow stream out of the suppressor means; (e) detecting the analyte ions in the second chromatography effluent flow stream.

公开(公告)号：EP1092977B1

公开(公告)日：2005-12-28

申请号：EP00122480.7

申请日：2000-10-13

申请人： Alltech Associates, Inc.

发明人： Anderson, James M. Jr. ,  Saari-Nordhaus, Raaidah ,  Benedict, Bart C. ,  Sims, Carl W. ,  Gurner, Yuri ,  Pham, Hung Anthony

IPC分类号： G01N30/96

CPC分类号： G01N30/96 ,  B01D15/367 ,  G01N30/34 ,  G01N2001/4016 ,  G01N2030/965

公开(公告)号：EP1099479A3

公开(公告)日：2001-08-08

申请号：EP01101801.7

申请日：1996-03-01

申请人： Alltech Associates, Inc.

发明人： Anderson, James M. Jr. ,  Saari-Nordhaus, Raaidah ,  Sims, Carl W. ,  Gerner, Yuri E.

IPC分类号： B01J39/06 ,  B01D15/08 ,  G01N30/96 ,  G01N30/52

CPC分类号： G01N27/453 ,  B01D15/361 ,  B01D15/3885 ,  B01J39/26 ,  G01N30/02 ,  G01N30/34 ,  G01N30/468 ,  G01N30/52 ,  G01N30/96 ,  G01N2030/285 ,  G01N2030/965 ,  G01N2030/0035 ,  B01D15/362

摘要： A method of detecting sample ions in an aqueous mobile phase comprises flowing the sample ions and the mobile phase through a stationary phase and applying an electrical potential across an ion exchange packing material includec in the stationary phase to thereby initiate electrolysis of water. The stationary phase is then, at least partially, regenerated by flowing of the electrolysis ions across the stationary phase. In a further aspect, the stationary phase is at least partially regenerated in the presence of sample ions.

摘要翻译： 检测水性流动相中的样品离子的方法包括使样品离子和流动相流过固定相，并在固定相中包含离子交换填充材料的电势施加电势，从而开始电解水。 然后通过电解离子流过固定相至少部分地使固定相再生。 另一方面，在存在样品离子的情况下，固定相至少部分再生。

公开(公告)号：EP1099479A2

公开(公告)日：2001-05-16

申请号：EP01101801.7

申请日：1996-03-01

申请人： Alltech Associates, Inc.

发明人： Anderson, James M. Jr. ,  Saari-Nordhaus, Raaidah ,  Sims, Carl W. ,  Gerner, Yuri E.

IPC分类号： B01J39/06 ,  B01D15/08 ,  G01N30/96 ,  G01N30/52

CPC分类号： G01N27/453 ,  B01D15/361 ,  B01D15/3885 ,  B01J39/26 ,  G01N30/02 ,  G01N30/34 ,  G01N30/468 ,  G01N30/52 ,  G01N30/96 ,  G01N2030/285 ,  G01N2030/965 ,  G01N2030/0035 ,  B01D15/362

摘要： A method of detecting sample ions in an aqueous mobile phase comprises flowing the sample ions and the mobile phase through a stationary phase and applying an electrical potential across an ion exchange packing material includec in the stationary phase to thereby initiate electrolysis of water.
The stationary phase is then, at least partially, regenerated by flowing of the electrolysis ions across the stationary phase.
In a further aspect, the stationary phase is at least partially regenerated in the presence of sample ions.

摘要翻译： 在wässrige包括流动的样品离子，并通过固定相，流动相的流动相检测样品离子和对面的离子交换包装材料includec施加到电势在固定相，由此所述的方法引发的电解水。 固定相是然后，至少部分地，通过在固定相上的电解离子的流动再生。 在进一步的方面中，所述固定相是至少在样品离子的存在下部分再生。

公开(公告)号：EP1640714A2

公开(公告)日：2006-03-29

申请号：EP05028383.7

申请日：2000-10-13

申请人： Alltech Associates, Inc.

发明人： Anderson, James M. Jr. ,  Saari-Nordhaus, Raaidah ,  Benedict, Bart C. ,  Sims, Carl W. ,  Gurner, Yuri ,  Pham, Hung Anthony

IPC分类号： G01N30/96

CPC分类号： G01N30/96 ,  B01D15/367 ,  G01N30/34 ,  G01N2001/4016 ,  G01N2030/965

摘要： A method of detecting analyte ions by continuous electrochemically suppressed ion chromatography comprising: (a) flowing analyte ions in an aqueous mobile phase comprising electrolyte through an analytical column separating means to form an aqueous chromatography effluent comprising separated analyte ions and electrolyte; (b) flowing the aqueous chromatography effluent through a suppressor means for splitting the chromatography effluent into a first chromatography effluent flow stream and a second chromatography effluent flow stream; (c) applying an electrical potential in the suppressor means such that electrolyte is electrochemically driven into the first chromatography effluent stream and away from the second chromatography effluent flow stream; (d) flowing the second chromatography effluent flow stream out of the suppressor means; (e) detecting the analyte ions in the second chromatography effluent flow stream.

摘要翻译： 通过连续电化学抑制的离子色谱检测分析物离子的方法，其包括：（a）通过分析柱分离装置将包含电解质的水性流动相中的分析物离子流动，以形成包含分离的分析物离子和电解质的含水层析流出物; （b）使含水层析流出物流过抑制剂装置，用于将色谱流出物分离成第一色谱流出物流和第二色谱流出物流; （c）在抑制器装置中施加电势使得电解质被电化学驱动进入第一色谱流出物流并且远离第二层析流出物流; （d）使第二层析流出物流流出抑制装置; （e）检测第二层析流出物流中的分析物离子。

公开(公告)号：EP1366817A3

公开(公告)日：2004-03-10

申请号：EP03020294.9

申请日：1996-03-01

申请人： Alltech Associates, Inc.

发明人： Anderson, James M., Jr. ,  Saari-Nordhaus, Raaidah ,  Sims, Carl W. ,  Gerner, Yuri E.

IPC分类号： B01J39/06 ,  B01D15/08 ,  G01N30/52 ,  G01N30/96

CPC分类号： G01N27/453 ,  B01D15/361 ,  B01D15/3885 ,  B01J39/26 ,  G01N30/02 ,  G01N30/34 ,  G01N30/468 ,  G01N30/52 ,  G01N30/96 ,  G01N2030/285 ,  G01N2030/965 ,  G01N2030/0035 ,  B01D15/362

摘要： A system for generating a high purity eluant that can be used in detecting sample ions comprises: a water source, an eluant generating source, and a fluid flow path that is in fluid communication with the water source, wherein the fluid flow path is the only path for liquid flow through the eluant generating source. By electrolysis of water and combining electrolysis ions with counter ions of a sample a high-purity eluant is formed.

公开(公告)号：EP1048351B1

公开(公告)日：2003-09-10

申请号：EP00115245.3

申请日：1996-03-01

申请人： Alltech Associates, Inc.

发明人： Anderson, James M, Jr. ,  Saari-Nordhaus, Raaidah ,  Sims, Carl W. ,  Gerner, Yuri E.

IPC分类号： B01J39/06 ,  B01D15/08 ,  G01N30/52 ,  G01N30/96

CPC分类号： G01N27/453 ,  B01D15/361 ,  B01D15/3885 ,  B01J39/26 ,  G01N30/02 ,  G01N30/34 ,  G01N30/468 ,  G01N30/52 ,  G01N30/96 ,  G01N2030/285 ,  G01N2030/965 ,  G01N2030/0035 ,  B01D15/362