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公开(公告)号:EP3817770A2
公开(公告)日:2021-05-12
申请号:EP19745402.8
申请日:2019-07-02
申请人: Amgen Inc. , Xencor, Inc.
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公开(公告)号:EP3737699A1
公开(公告)日:2020-11-18
申请号:EP19702165.2
申请日:2019-01-11
申请人: Amgen Inc.
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公开(公告)号:EP1891101B1
公开(公告)日:2013-05-22
申请号:EP06751903.3
申请日:2006-04-28
申请人: UCB Pharma, S.A. , AMGEN INC.
发明人: PASZTY, Christopher , ROBINSON, Martyn, Kim , GRAHAM, Kevin , HENRY, Alistair, James , HOFFMANN, Kelly, Sue , LATHAM, John , LAWSON, Alastair , LU, Hsieng, Sen , POPPLEWELL, Andy , SHEN, Wenyan , WINKLER, David , WINTERS, Aaron, George
CPC分类号: C07K16/22 , A61K39/3955 , A61K45/06 , A61K47/60 , A61K2039/505 , C07K14/76 , C07K14/79 , C07K16/18 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/30
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公开(公告)号:EP3990493A1
公开(公告)日:2022-05-04
申请号:EP20743449.9
申请日:2020-06-26
申请人: Amgen Inc.
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公开(公告)号:EP1805219A1
公开(公告)日:2007-07-11
申请号:EP05823196.0
申请日:2005-10-19
申请人: Amgen, Inc
IPC分类号: C07K16/22 , C12N15/13 , C07K16/46 , C12P21/08 , C12N15/20 , A61K39/385 , A61K39/395 , A61P35/00 , A61P9/00 , G01N33/68 , G01N33/577
CPC分类号: C07K16/22 , A61K2039/505 , C07K2317/21 , C07K2317/56 , C07K2317/73 , C07K2317/76
摘要: Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies.
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公开(公告)号:EP2220118A2
公开(公告)日:2010-08-25
申请号:EP08855691.5
申请日:2008-11-21
申请人: Amgen Inc.
发明人: QIAN, Xueming , GRAHAM, Kevin , SHIMAMOTO, Grant , TIPTON, Barbara S. , TSAI, Mei-Mei , WINTERS, Aaron George , ZHANG, Li
IPC分类号: C07K16/18 , A61K39/395
CPC分类号: C07K16/18 , A61K2039/505 , C07K2317/24 , C07K2317/92
摘要: The present invention relates to binding agents for WISE such as antibodies, and includes for their manufacture and use.
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公开(公告)号:EP2015776A1
公开(公告)日:2009-01-21
申请号:EP07761070.7
申请日:2007-04-20
申请人: Amgen Inc.
发明人: SHEN, Wenyan , GRAHAM, Kevin , WINTERS, Katherine, Ann , VENIANT-ELLISON, Murielle , BOONE, Thomas, Charles
IPC分类号: A61K39/395 , C07K14/605 , C07K16/26
CPC分类号: C07K16/26 , A61K2039/505 , C07K2317/21 , C07K2317/76 , C07K2319/00 , C07K2319/30
摘要: Compositions comprising antibodies that bind glucagon linked to GLP-I compounds are provided, as well as methods of using the compositions for treating, for example, metabolic disorders, enhancing insulin expression, and promoting insulin secretion in a subject.
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公开(公告)号:EP1891101A2
公开(公告)日:2008-02-27
申请号:EP06751903.3
申请日:2006-04-28
申请人: UCB Pharma, S.A. , AMGEN INC.
发明人: PASZTY, Christopher , ROBINSON, Martyn, Kim , GRAHAM, Kevin , HENRY, Alistair, James , HOFFMANN, Kelly, Sue , LATHAM, John , LAWSON, Alastair , LU, Hsieng, Sen , POPPLEWELL, Andy , SHEN, Wenyan , WINKLER, David , WINTERS, Aaron, George
CPC分类号: C07K16/22 , A61K39/3955 , A61K45/06 , A61K47/60 , A61K2039/505 , C07K14/76 , C07K14/79 , C07K16/18 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/30
摘要: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
摘要翻译: 提供了与硬骨素蛋白的表位和硬骨素结合剂相关的组合物和方法,例如能够结合硬骨素的抗体。
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公开(公告)号:EP3985015A1
公开(公告)日:2022-04-20
申请号:EP21188463.0
申请日:2006-04-28
申请人: UCB Pharma S.A. , Amgen, Inc
发明人: PASZTY, Christopher , ROBINSON, Martyn Kim , GRAHAM, Kevin , HENRY, Alistair James , HOFFMAN, Kelly Sue , LATHAM, John , LAWSON, Alastair , LU, Hsieng Sen , POPPLEWELL, Andy , SHEN, Wenyan , WINKLER, David , WINTERS, Aaron George
摘要: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin-binding agents, such as antibodies capable of binding to sclerostin, are provided.
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公开(公告)号:EP3790904A1
公开(公告)日:2021-03-17
申请号:EP19727555.5
申请日:2019-05-08
申请人: Amgen Inc.
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