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1.发明公开NEW ALKYL ESTERS OF CYCLIC AMINO ALCOHOLS WITH MUSCARINIC M3 RECEPTOR ANTAGONIST ACTIVITY, USEFUL FOR TREATING E.G. CHRONIC BRONCHIAL OBSTRUCTION, ASTHMA AND OVERACTIVE BLADDER 审中-公开NEW烷基酯OFF环氨基醇与毒蕈碱M3REZEPTORANTAGONOSTENAKTIVITÄT用于治疗慢性支气管阻塞，哮喘治疗或通过主动膀胱
公开(公告)号：EP2013172A1
公开(公告)日：2009-01-14
申请号：EP07748054.9
申请日：2007-04-23
申请人： AstraZeneca AB
IPC分类号： C07D211/46 , A61K31/4409 , A61K31/4535 , A61K31/4545 , A61P11/00 , A61P13/10 , C07D401/12 , C07D409/12
CPC分类号： C07D211/48 , C07D409/12
摘要： The invention provides compounds of formula (I), wherein R1, R2, R3, R4, R5 and X are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them, a process for preparing pharmaceutical compositions and their use in therapy (I).
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公开(公告)号：EP1114029A1
公开(公告)日：2001-07-11
申请号：EP99949512.0
申请日：1999-09-13
申请人： AstraZeneca AB
IPC分类号： C07D213/60 , C07D237/08 , C07D239/26 , C07D207/267 , C07C321/28 , C07C235/46 , A61K31/44 , A61K31/50 , A61K31/165
CPC分类号： C07D207/26 , C07C43/23 , C07C217/74 , C07C235/42 , C07C323/21 , C07C323/42 , C07D213/61 , C07D213/64 , C07D237/08 , C07D239/26 , C07D277/24
摘要： The invention relates to novel pyridyl derivatives (I), their use as medicaments, pharmaceutical formulations including them and methods for their preparation.
摘要翻译： 本发明涉及新的吡啶基衍生物（I），它们作为药物的用途，包括它们的药物制剂以及它们的制备方法。
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3.发明授权N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES 有权N-吡嗪phenylsulfonamides及其用于疾病治疗的介导的趋化因子
公开(公告)号：EP1467976B1
公开(公告)日：2011-11-23
申请号：EP03700655.8
申请日：2003-01-14
申请人： AstraZeneca AB
IPC分类号： C07D241/22 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/04 , C07D413/12 , A61K31/4965 , A61P11/06 , A61P29/00
CPC分类号： C07D231/12 , C07D233/56 , C07D241/22 , C07D249/08 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07F7/0812
摘要： The invention provides N-pyrazinyl-phenylsulphonamides of formula (I) for use in the treatment of chemokine mediated diseases. Particularly inflammatory diseases, such as asthma.
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4.发明公开7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS 2 ADRENOCEPTOR AGONISTS 审中-公开7-（2-氨基-1-羟基乙基）-4-羟基苯并噻唑-2（3H） - 邻苯二甲酸酯AGONISTEN AM 2-ADRENOCEPTOR
公开(公告)号：EP1957471A1
公开(公告)日：2008-08-20
申请号：EP06769630.2
申请日：2006-08-28
申请人： AstraZeneca AB
IPC分类号： C07D277/68 , A61K31/428 , A61P11/00 , A61P11/06
CPC分类号： C07D277/68
摘要： The present invention provides compounds of formula (I) wherein e, R1, R2, R3, R4, R5, R4', R5', R6, R7, A, D, m and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
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公开(公告)号：EP1915354A1
公开(公告)日：2008-04-30
申请号：EP06769596.5
申请日：2006-08-03
申请人： AstraZeneca AB
IPC分类号： C07D277/68 , A61K31/428 , A61K31/4439 , A61K31/454 , A61P11/06 , A61P11/08 , C07D417/12
CPC分类号： C07D277/68 , C07D417/12
摘要： The present invention provides compounds of formula (I) wherein e, R1, R2, R3, R4, R5, R4, R5, R6, R7, R7a, R7b, A, D, m and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
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公开(公告)号：EP2013197A1
公开(公告)日：2009-01-14
申请号：EP07716036.4
申请日：2007-03-06
申请人： AstraZeneca AB
发明人： ALCARAZ, Lilian , BAILEY, Andrew , COX, Rhona , MEGHANI, Premji , PAIRAUDEAU, Garry , STOCKS, Michael
IPC分类号： C07D401/12 , A61K31/137 , A61K31/428 , A61K31/445 , A61K31/454 , A61K31/4704 , A61K31/4709 , A61P11/00 , A61P11/06 , A61P11/08 , C07C211/36 , C07D211/26 , C07D215/26 , C07D417/12
CPC分类号： C07D215/26 , C07D401/12 , C07D417/12
摘要： The present invention relates to compounds according to formula (I), a process for preparing them, the intermediate compounds of the process and the use of the compounds in the manufacture of a medicament for use in treating diseases such as ARDS, pulmonary emphysema, bronchitis, bronchiectasis, COPD, asthma and rhinitis. The compounds are beta2 adrenoreceptor agonists.
摘要翻译： 本发明涉及式（I）化合物，其制备方法，该方法的中间体化合物以及该化合物在制备用于治疗ARDS，肺气肿，支气管炎等疾病的药物中的用途 ，支气管扩张，COPD，哮喘和鼻炎。 这些化合物是β2肾上腺素受体激动剂。
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7.发明公开7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS BETA 2 ADRENOCEPTOR AGONISTS 审中-公开7-（2-氨基-1-羟基乙基）-4-羟基苯并噻唑-2（3H） - 邻氨基苯并二氮丙啶-2-对映体
公开(公告)号：EP1937656A1
公开(公告)日：2008-07-02
申请号：EP06784115.5
申请日：2006-08-28
申请人： AstraZeneca AB
发明人： BAILEY, Andrew , BONNERT, Roger , CONNOLLY, Stephen , INGALL, Anthony , PAIRAUDEAU, Garry , STOCKS, Michael
IPC分类号： C07D277/68 , A61K31/428 , A61P11/00 , A61P11/06
CPC分类号： C07D277/68
摘要： The present invention provides compounds of formula (I) wherein the variables are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
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公开(公告)号：EP0984961B1
公开(公告)日：2001-06-20
申请号：EP98914202.1
申请日：1998-03-27
申请人： AstraZeneca AB
发明人： CHESHIRE, David , CLADINGBOEL, David , COOPER, Martin , HARDERN, David , HIRST, Simon , MANNERS, Carol , STOCKS, Michael
IPC分类号： C07D405/04 , C07D405/12 , C07D213/30 , C07D209/12 , C07D401/12 , C07D413/12 , A61K31/44
CPC分类号： C07D213/30 , C07D213/64 , C07D213/85 , C07D401/12 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12
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