专利检索 ap:("Aventis Pharmaceuticals, Inc." OR "AXYS PHARMACEUTICALS, INC.") AND inv:"LINK, John" 第 1 页

1.

发明公开
MORPHOLINE AND TETRAHYDROPYRAN DERIVATIVES AND THEIR USE AS CATHEPSIN INHIBITORS 审中-公开
标题翻译：吗啉和四氢衍生物及其作为抑制剂CATHEPSIN

公开(公告)号：EP1515726A1

公开(公告)日：2005-03-23

申请号：EP03739296.6

申请日：2003-06-25

申请人： Aventis Pharmaceuticals, Inc. , AXYS PHARMACEUTICALS, INC.

发明人： GRAUPE, Michael , PALMER, James, T. , PATTERSON, John, W. , PICKETT, Stephen, D. , ALDOUS, David, J. , THURAIRATNAM, Sukanthini , TIMM, Andreas, P. , HALLEY, Frank , LAI, Justine , LINK, John , LI, Jiayao

IPC分类号： A61K31/5375 , C07D271/06 , C07D263/56 , C07D413/12 , C07D498/04 , C07D213/40 , C07D295/185 , A61K31/5377 , A61K31/4245

CPC分类号： C07D213/40 , A61K31/4245 , A61K31/5375 , A61K31/5377 , C07C317/44 , C07C323/60 , C07D205/08 , C07D207/24 , C07D213/75 , C07D223/12 , C07D263/32 , C07D263/56 , C07D271/06 , C07D271/10 , C07D277/26 , C07D277/64 , C07D285/08 , C07D295/185 , C07D413/04 , C07D413/12

摘要： The present invention relates to novel cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.

2.

发明公开
NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS 审中-公开
标题翻译：新化合物和组合物作为抑制剂CATHEPSIN

公开(公告)号：EP1383748A2

公开(公告)日：2004-01-28

申请号：EP01988420.4

申请日：2001-12-24

申请人： AXYS PHARMACEUTICALS, INC. , Halley, Frank , Aventis Pharmaceuticals Inc.

发明人： GRAUPE, Michael , PATTERSON, John , PICKETT, Stephen, D. , LINK, John , LI, Jiayao , ALDOUS, David , THURAIRATNAM, Sukanthini , TIMM, Andreas , HALLEY, Frank , LAI, Justine

IPC分类号： C07D263/56 , C07D277/64 , C07D295/18 , C07C317/44 , C07D271/06 , C07C323/60 , C07D205/08 , C07D277/26 , C07C317/50 , C07D207/26 , C07D233/10 , C07D498/04 , C07D271/10 , C07D413/04 , C07D223/12 , A61K31/16 , A61P29/00

CPC分类号： C07D207/273 , A61K31/5375 , A61K31/5377 , C07C317/44 , C07C323/60 , C07D205/08 , C07D207/24 , C07D213/40 , C07D223/10 , C07D223/12 , C07D263/32 , C07D263/56 , C07D271/06 , C07D271/10 , C07D277/26 , C07D277/64 , C07D285/08 , C07D295/185 , C07D413/04 , C07D413/12 , Y02A50/411

摘要： The present invention relates to novel selective cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.