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    A METHOD FOR SCREENING OF GENES CONFERRING INCREASED TOLERANCE TO HERBICIDES
    3.
    发明公开
    A METHOD FOR SCREENING OF GENES CONFERRING INCREASED TOLERANCE TO HERBICIDES 审中-公开
    筛选增加对除草剂耐受性的基因的方法

    公开(公告)号：EP3227448A1

    公开(公告)日：2017-10-11

    申请号：EP15798405.5

    申请日：2015-11-20

    Applicant: BASF SE

    Inventor： TRESCH, Stefan ,  APONTE, Raphael ,  LERCHL, Jens ,  HUTZLER, Johannes

    IPC: C12N15/82 ,  G01N21/64

    CPC classification number: C12N15/8274 ,  A01N43/00 ,  G01N21/6486

    Abstract: The present invention relates to a method for identifying a polynucleotide encoding a polypeptide which confers herbicide tolerance to a plant by measuring photosynthetic quantum yield wherein an increase in the electron transport rate of the samples of the transformed plant as compared to the sample of the control plant is indicative for a herbicide tolerance conferring activity of said candidate polypeptide.

    Abstract translation: 本发明涉及通过测量光合量子产量来鉴定编码赋予植物除草剂耐受性的多肽的多核苷酸的方法，其中与对照植物的样品相比，转化植物样品的电子传递速率增加 指示赋予所述候选多肽活性的除草剂耐受性。

    SUBSTITUTED 1,2,5-OXADIAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES III
    6.
    发明公开
    SUBSTITUTED 1,2,5-OXADIAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES III 审中-公开
    取代的1,2,5-恶二唑及其作为除草剂III

    公开(公告)号：EP2780340A1

    公开(公告)日：2014-09-24

    申请号：EP12787442.8

    申请日：2012-11-16

    Applicant: BASF SE

    Inventor： KRAUS, Helmut ,  WITSCHEL, Matthias ,  SEITZ, Thomas ,  NEWTON, Trevor William ,  PARRA RAPADO, Liliana ,  APONTE, Raphael ,  KREUZ, Klaus ,  GROßMANN, Klaus ,  LERCHL, Jens ,  EVANS, Richard R.

    IPC: C07D413/12 ,  C07D471/04 ,  A01N43/82

    CPC classification number: A01N43/82 ,  C07D413/12 ,  C07D471/04

    Abstract: The present invention relates to substituted 1,2,5-oxadiazole compounds of the formula I and the N-oxidesand saltsthereof and to compositions comprising the same. The invention also relates to the use of the 1,2,5-oxadiazole compounds or of the compositions comprising such compounds for controlling unwanted vegetation. Wherein X
    1 is N or CR
    1 ; X
    2 is N or CR
    2 ; X
    4 is N or CR
    4 ; provided that a least one of X
    1 , X
    2 and X
    4 is N; R is e.g. selected from the group consisting of hydrogen, cyano, nitro, halogen, C
    1 -C
    6 -alkyl, C
    3 -C
    7 -cycloalkyl, C
    3 -C
    7 -cycloalkyl-C
    1 -C
    4 -alkyl, C
    1 -C
    6 -haloalkyl, C
    2 -C
    6 -alkenyl, C
    2 -C
    6 -haloalkenyl, C
    2 -C
    6 -alkynyl, C
    2 -C
    6 -haloalkynyl, C
    1 -C
    4 -alkoxy-C
    1 -C
    4 -alkyl, C
    1 -C
    4 -haloalkoxy-C
    1 -C
    4 -alkyl, O-R
    a , Z-S(O)
    n -R
    b , Z-C(=O)-R
    c , Z-C(=O)-OR
    d , Z-C(=O)-N R
    e R
    f , Z-NR
    g R
    h , Z-phenyl and Z-heterocyclyl; R
    1 is e.g. selected from the group consisting of Z
    1 -cyano, halogen, nitro, C
    1 -C
    8 -alkyl, C
    2 -C
    8 -alkenyl, C
    2 -C
    8 -alkynyl, C
    1 -C
    8 -haloalkyl, C
    1 -C
    8 -alkoxy, C
    1 -C
    4 -alkoxy-C
    1 -C
    4 -alkyl, Z
    1 -C
    1 -C
    4 -alkoxy-C
    1 -C
    4 -alkoxy, C
    1 -C
    4 -alkylthio-C
    1 -C
    4 -alkyl, Z
    1 -C
    1 -C
    4 -alkylthio-C
    1 -C
    4 -alkylthio, C
    2 -C
    6 -alkenyloxy, C
    2 -C
    6 -alkynyloxy, C
    1 -C
    6 -haloalkoxy, C
    1 -C
    4 -haloalkoxy-C
    1 -C
    4 -alkyl, Z
    1 -C
    1 -C
    4 -haloalkoxy-C
    1 -C
    4 -alkoxy, Z
    1 -S(O)
    k -R
    1b , Z
    1 -phenoxy and Z
    1 -heterocyclyloxy; R
    2 , R
    3 are identical or different and e.g. selected from the group consisting of hydrogen, halogen, Z
    2 -OH, Z
    2 -NO
    2 , Z
    2 -cyano, C
    1 -C
    6 -alkyl, C
    2 -C
    8 -alkenyl, C
    2 -C
    8 -alkynyl, Z
    2 -C
    3 -C
    10 -cycloalkyl, Z
    2 -C
    3 -C
    10 -cycloalkoxy, C
    1 -C
    8 -haloalkyl, Z
    2 -C
    1 -C
    8 -alkoxy, Z
    2 -C
    1 -C
    8 -haloalkoxy, Z
    2 -C
    1 -C
    4 -alkoxy-C
    1 -C
    4 -alkoxy, Z
    2 -C
    1 -C
    4 -alkylthio-C
    1 -C
    4 -alkylthio, etc., R
    4 is selected from the group consisting of hydrogen, halogen, cyano, nitro, C
    1 -C
    4 -alkyl and C
    1 -C
    4 -haloalkyl; R
    5 is selected from the group consisting of hydrogen, halogen, cyano, nitro, C
    1 -C
    4 -alkyl and C
    1 -C
    4 -haloalkyl.

    SUBSTITUTED 1,2,5-OXADIAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES II
    7.
    发明公开
    SUBSTITUTED 1,2,5-OXADIAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES II 审中-公开
    取代的1,2,5-恶二唑及其作为除草剂II

    公开(公告)号：EP2780339A1

    公开(公告)日：2014-09-24

    申请号：EP12787713.2

    申请日：2012-11-15

    Applicant: BASF SE

    Inventor： KRAUS, Helmut ,  WITSCHEL, Matthias ,  SEITZ, Thomas ,  NEWTON, Trevor William ,  PARRA RAPADO, Liliana ,  APONTE, Raphael ,  KREUZ, Klaus ,  GROSSMANN, Klaus ,  LERCHL, Jens ,  EVANS, Richard R.

    IPC: C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  A01N43/82

    CPC classification number: C07D413/12 ,  A01N43/82 ,  C07D409/12 ,  C07D413/14 ,  C07D417/12

    Abstract: The present invention relates to substituted 1,2,5-oxadiazole compounds of the formula (I) and the N-oxides and salts thereof and to compositions comprising the same. The invention also relates to the use of the 1,2,5-oxadiazole compounds or of the compositions comprising such compounds for controlling unwanted vegetation. Furthermore, the invention relates to methods of applying such compounds. In formula I, the variables have the following meanings: R is e.g. hydrogen, cyano, nitro, halogen, C
    1 -C
    6 -alkyl, C
    3 -C
    7 -cycloalkyl, C
    3 -C
    7 -cycloalkyl-C
    1 -C
    4 -alkyl, C
    1 -C
    6 -haloalkyl, C
    2 -C
    6 -alkenyl, C
    2 -C
    6 -haloalkenyl, C
    2 -C
    6 -alkynyl, C
    2 -C
    6 -haloalkynyl, C
    1 -C
    4 -alkoxy-C
    1 -C
    4 -alkyl, C
    1 -C
    4 -haloalkoxy-C
    1 -C
    4 -alkyl, O-R
    a , Z-S(O)
    n -R
    b , Z-C(=O)-R
    c , Z-C(=O)-OR
    d , Z-C(=O)-NR
    e R
    f , Z-NR
    g R
    h , Z-phenyl or Z-heterocyclyl;CYC is a bi- or tricyclic radical of the following formulae Cyc-1 or Cyc-2 where # is the point of attachment of the bicyclic radical to the carbonyl group, Q, Q' independently of each other are e.g. a fused 5-, 6-, 7-, 8-, 9- or 10-membered carbocycle or a fused 5-, 6-, 7-, 8-, 9- or 10-membered heterocycle; R
    1 is e.g. Z
    1 -cyano, halogen, nitro, C
    1 -C
    8 -alkyl, C
    2 -C
    8 -alkenyl, C
    2 -C
    8 -alkynyl, C
    1 -C
    8 -haloalkyl, C
    1 -C
    8 -alkoxy, C
    1 -C
    4 -alkoxy-C
    1 -C
    4 -alkyl, Z
    1 -C
    1 -C
    4 -alkoxy-C
    1 -C
    4 -alkoxy, C
    1 - C
    4 -alkylthio-C
    1 -C
    4 -alkyl, Z
    1 -C
    1 -C
    4 -alkylthio-C
    1 -C
    4 -alkylthio, C
    2 -C
    6 -alkenyloxy, C
    2 -C
    6 - alkynyloxy, C
    1 -C
    6 -haloalkoxy, C
    1 -C
    4 -haloalkoxy-C
    1 -C
    4 -alkyl, Z
    1 -C
    1 -C
    4 -haloalkoxy-C
    1 -C
    4 - alkoxy, Z
    1 -S(O)
    k -R
    1b , Z
    1 -phenoxy or Z
    1 -heterocyclyloxy; R
    3 is e.g. hydrogen, halogen, Z
    3 -OH, Z
    3 -NO
    2 , Z
    3 -cyano, C
    1 -C
    6 -alkyl, C
    2 -C
    8 - alkenyl, C
    2 -C
    8 -alkynyl, Z
    2 -C
    3 -C
    10 -cycloalkyl, Z
    3 -C
    3 -C
    10 -cycloalkoxy, C
    1 -C
    8 -haloalkyl, Z
    3 -C
    1 -C
    8 -alkoxy, Z
    3 -C
    1 -C
    8 -haloalkoxy, Z
    3 -C
    1 -C
    4 -alkoxy-C
    1 -C
    4 -alkoxy, Z
    3 -C
    1 -C
    4 -alkylthio-C
    1 -C
    4 -alkylthio, Z
    3 -C
    2 -C
    8 -alkenyloxy, Z
    3 -C
    2 -C
    8 -alkynyloxy, Z
    3 -C
    1 -C
    8 -haloalkoxy, Z
    3 -C
    2 -C
    8 - haloalkenyloxy, Z
    3 -C
    2 -C
    8 -haloalkynyloxy, Z
    3 -C
    1 -C
    4 -haloalkoxy-C
    1 -C
    4 -alkoxy, Z
    3 -(tri-C
    1 - C
    4 -alkyl)silyl, Z
    3 -S(O)
    k -R
    3b , Z
    3 -C(=O)-R
    3c , Z
    3 -C(=O)-OR
    3d , Z
    3 -C(=O)-NR
    3e R
    3f , Z
    3 - NR
    3g R
    3h , Z
    3a -phenyl or Z
    3a -heterocyclyl; R
    4 is hydrogen, halogen, cyano, nitro, C
    1 -C
    4 -alkyl or C
    1 -C
    4 -haloalkyl; R
    5 is hydrogen, halogen, C
    1 -C
    4 -alkyl or C
    1 -C
    4 -haloalkyl; provided that at least one of the radicals R
    4 and R
    5 is different from hydrogen; n is 0, 1 or 2; k is 0, 1 or 2; and the variables Z, Z
    1 , Z
    2 , Z
    3 , Z
    3a , R
    a , R
    b , R
    1b , R
    2b , R
    3b , R
    c , R
    2c , R
    3c , R
    d , R
    3d , R
    e , R
    f , R
    3e , R
    3f , R
    g , R
    h , R
    2g , R
    2h , R
    3g and R
    3h have the meanings given in the claims.

    PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES
    8.
    发明公开
    PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES 审中-公开
    植物对除草剂的耐受性增加

    公开(公告)号：EP2773764A1

    公开(公告)日：2014-09-10

    申请号：EP12845366.9

    申请日：2012-10-30

    Applicant: BASF SE

    Inventor： HUTZLER, Johannes ,  TRESCH, Stefan ,  MIETZNER, Thomas ,  WITSCHEL, Matthias ,  LERCHL, Jens ,  APONTE, Raphael ,  PARRA RAPADO, Liliana ,  PAULIK, Jill, Marie

    IPC: C12N15/82 ,  C12N5/04 ,  C12N5/14 ,  C12N15/05 ,  C07K14/415 ,  A01H1/00 ,  A01H5/00

    CPC classification number: C12N15/8274 ,  A01N43/40 ,  A01N43/60 ,  C12N9/0069 ,  C12N9/1085 ,  C12Y113/11027

    Abstract: A method for controlling undesired vegetation at a plant cultivation site is provided, which comprises the steps of providing, at said site, a plant comprising at least a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a coumarone-derivative herbicide and /or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a coumarone-derivative herbicide, and applying to said site an effective amount of said herbicide. Plants comprising mut-HPPD and methods of obtaining such plants are also provided.

    Abstract translation: 提供了用于防治植物栽培位点处的不希望植物的方法，其包括以下步骤：在所述位点提供包含至少编码野生型羟苯基丙酮酸双加氧酶或突变羟苯基丙酮酸双加氧酶（mut- HPPD），其是抗性或耐受性对香豆酮衍生物除草剂和/或编码野生型尿茄呢转移酶或核苷酸序列的突变的尿茄呢转移酶（MUT-HST），其是抗性或耐受性对香豆酮衍生物除草剂， 并向所述部位施用有效量的所述除草剂。 还提供了包含mut-HPPD的植物和获得这种植物的方法。

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