公开(公告)号：EP3377554A1

公开(公告)日：2018-09-26

申请号：EP16795381.9

申请日：2016-11-16

Applicant: BASF SE

Inventor： PAZICKY, Marek ,  PACIELLO, Rocco ,  LINDER, David ,  BLANCHOT, Mathieu ,  FISCHER, Wolfgang

IPC: C08G63/82 ,  C07C67/03

CPC classification number: C07C67/327 ,  C07C51/377 ,  C07C67/03 ,  C08G63/06 ,  C08G63/823 ,  C07C69/675 ,  C07C69/54 ,  C07C57/04

Abstract: The invention relates to 3-hydroxypropionic acid esters, obtained by conversion of ethylene oxide with carbon monoxide in the presence of a cobalt catalyst, wherein poly-3-hydroxypropionate is obtained; and transesterification of the poly-3-hydroxypropionate with an alcohol in the presence of a transeseterification catalyst, wherein the 3-hydroxypropionic acid esters are obtained. The transesterification catalyst is a compound of the formula MLx, wherein M stands for a metal of the 2nd, 3rd, or 4th main group or the 3rd to 8th secondary group of the periodic system of the elements, L stands for a ligand, which directly bonds to an M via a C, an O, a P, an S and/or an N atom, and x is a whole number from 2 to 6.

公开(公告)号：EP3102637B1

公开(公告)日：2018-04-11

申请号：EP15704492.6

申请日：2015-02-04

Applicant: BASF SE

Inventor： FELLE, Max Fabian ,  GRANSTRÖM, Mari ,  LINDER, David ,  KORDE, Shilpa S. ,  SAMEL, Amarish

IPC: C09B69/10 ,  C09B67/02 ,  C07K1/22 ,  C07K16/00

CPC classification number: C07K1/22 ,  B01J20/288 ,  B01J20/289 ,  B01J20/3085 ,  B01J20/3204 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/3261 ,  B01J2220/49 ,  C07K16/00 ,  C09B67/0097 ,  C09B69/101 ,  G01N33/583 ,  G01N33/6857

Abstract: The present invention relates to novel adsorbents applicable a process for the separation or purification of antibodies, antibody fragments or engineered variants thereof, which comprise anthraquinone dye ligands; corresponding purification processes; and corresponding analytical or preparative separation kits.

公开(公告)号：EP3102637A1

公开(公告)日：2016-12-14

申请号：EP15704492.6

申请日：2015-02-04

Applicant: BASF SE

Inventor： FELLE, Max Fabian ,  GRANSTRÖM, Mari ,  LINDER, David ,  KORDE, Shilpa S. ,  SAMEL, Amarish

IPC: C09B69/10 ,  C09B67/02 ,  C07K1/22 ,  C07K16/00

CPC classification number: C07K1/22 ,  B01J20/288 ,  B01J20/289 ,  B01J20/3085 ,  B01J20/3204 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/3261 ,  B01J2220/49 ,  C07K16/00 ,  C09B67/0097 ,  C09B69/101 ,  G01N33/583 ,  G01N33/6857

Abstract: The present invention relates to novel adsorbents applicable a process for the separation or purification of antibodies, antibody fragments or engineered variants thereof, which comprise anthraquinone dye ligands; corresponding purification processes; and corresponding analytical or preparative separation kits.

Abstract translation: 本发明涉及适用新吸附剂为抗体，抗体片段的分离或纯化方法或其改造的变体，其包含蒽醌染料配体; CORRESPONDING纯化过程; 和相应的分析或制备分离试剂盒。