摘要:
A membrane (10) and a method for making a membrane (10) are disclosed. The membrane (10) includes a polymeric matrix (16) and a particulate material immobilized within the matrix (16). The membrane (10) may include a support (18) within the core of the mebrane (10) and may further include a skin (19). The membrane (10) may find particular application in methods and apparatus for removing organic compounds from a biological fluid as part of a pathogen inactivation treatment.
摘要:
A priming indicator for a fluid infusion system includes a luer cap (20) or other component of the infusion system having an indicator surface (22) covered by a membrane (24). The membrane exhibits a first visual characteristic, such as being opaque, when dry and exhibits a second characteristic, such as becoming less opaque, when wet. Once the membrane becomes wet, indicia on the surface, which may be provided on a rod at least partially covered by the membrane, becomes visible, thereby indicating an intravenous tube to which the luer cap is secured has been primed or is nearly primed. The indicator may alternately be employed at an upstream end of an infusion set, such as at the port of a medical bag providing a supply of fluid, to indicate a low level of fluid in the medical bag.
摘要:
Devices for removing compounds from a biological fluid are disclosed. The devices (20) include sorbent beads (22) applied to an adhesive-surface (26, 28) of support (24). The devices (20) may be used in 'batch-type' or 'flow-through' systems.
摘要:
Membranes and methods for making membranes are disclosed. The membranes (10) include a polymeric matrix (16) and a particulate material immobilized within the matrix. The membrane may further include a skin layer (19) having randomly spaced surface pores (21). The membranes may find particular application in methods and apparatus for removing organic compounds from a biological fluid as part of a pathogen inactivation treatment.
摘要:
Microporous membranes (10) comprising polyvinylidene difluoride and methods for making such membranes are disclosed. The membranes (10), which are not crosslinked and are not contacted with a strong alkali solution during manufacture, are wettable by aqueous solution even after repeated wetting and drying. The membrane includes a support (18) and surfaces (11) treated with a hydrophilic coating. Separately, such membranes are also useful in apparatus (60) for separating a biological fluid into two or more components.
摘要:
L'invention concerne des membranes à double peau utiles comme membranes unidirectionnelles ou de rectification réduisant la refiltration de molécules dissoutes en dialyse, et améliorant l'apport de constituants nutritifs ainsi que la récupération de produits dans des bioréacteurs à membranes. Les membranes sont des matières polymères à double peau se présentant de préférence sous la forme de fibres creuses. Lesdites membranes présentent des peaux en polymère sur les faces opposées, avec différentes caractéristiques de coefficients de porosité ou de tamisage. Les membranes sont formées par extrusion d'un polymère dissous dans un solvant, tout en mettant en contact au moins une surface avec un non-solvant miscible audit solvant. On met en contact l'autre surface avec un non-solvant. Soit les deux non-solvants sont différents l'un de l'autre soit un des non-solvants contient un additif soluble changeant la porosité de la peau formée sur le polymère extrudé dissous. On obtient des dispositifs de dialyse améliorés en utilisant des faisceaux des membranes à fibres creuses comme moyen de dialyse présentant des propriétés de rectification. On obtient des bioréacteurs améliorés en utilisant des faisceaux de membranes à fibres creuses comme milieu de croissance ayant des propriétés de rectification.