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公开(公告)号：EP1476181A4
公开(公告)日：2008-11-19
申请号：EP03731987
申请日：2003-01-17
申请人： BIOGEN IDEC INC
发明人： LIN KOCHUNG , PEPINSKY R BLAKE , CHEN LING LING , HESS DONNA M , LIN EDWARD Y , PETTER RUSSELL C , BAKER DARREN P
IPC分类号： A61K31/522 , A61K31/7056 , A61K31/7072 , A61K38/21 , A61K38/31 , A61K39/29 , A61K45/06 , A61K47/30 , A61K47/48 , A61K51/06 , A61P31/12 , A61P31/14 , C08G59/14 , C08G65/32 , C08G65/329 , C08L71/02 , C11D3/386
CPC分类号： C08G65/329 , A61K47/60 , C08L2203/02
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公开(公告)号：EP1499308A4
公开(公告)日：2006-05-24
申请号：EP03726198
申请日：2003-04-04
申请人： BIOGEN IDEC INC
发明人： LEE WEN-CHERNG , SUN LIHONG , SHAN FENG , CHUAQUI CLAUDIO , ZHENG ZHONGLI , PETTER RUSSELL C
IPC分类号： A61K31/36 , A61K31/395 , A61K31/41 , A61K31/435 , A61K31/4439 , A61K31/4545 , A61K31/517 , A61P1/16 , A61P9/00 , A61P11/00 , A61P13/12 , A61P17/00 , A61P21/00 , A61P27/02 , A61P35/00 , A61P35/04 , A61P43/00 , C07D401/04 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07D453/00 , C07D471/04 , C07D487/08 , C07D519/00
CPC分类号： C07D471/04 , C07D401/04 , C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D487/08
摘要： Compounds of formula (I) possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of the general formula (I).
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公开(公告)号：EP1596656A4
公开(公告)日：2006-10-18
申请号：EP04710613
申请日：2004-02-12
申请人： BIOGEN IDEC INC
发明人： LEE WEN-CHERNG , SUN LIHONG , SHAN FENG , CHUAQUI CLAUDIO , CORNEBISE MARK , PONTZ TIMOTHY W , CARTER MARYBETH , SINGH JUSWINDER , BORIACK-SJODIN PAULA ANN , LING LEONA , PETTER RUSSELL C
IPC分类号： C07D401/14 , A01N43/40 , A01N43/42 , A01N43/58 , A01N43/60 , A61K31/44 , A61K31/4427 , A61K31/47 , A61K31/495 , A61K31/4965 , A61K31/497 , A61K31/50 , A61K31/501 , A61K31/54 , A61P11/00 , A61P35/00 , C07D20060101 , C07D401/04 , C07D405/14 , C07D407/14 , C07D413/14 , C07D471/04
CPC分类号： C07D401/14 , C07D401/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04
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