-
公开(公告)号：EP1682543B1
公开(公告)日：2010-08-18
申请号：EP04791030.2
申请日：2004-10-29
IPC分类号： C07D451/10 , A61K31/46 , A61P11/00
CPC分类号： C07D451/10
摘要： The invention relates to novel tiotropium salts, methods for the production thereof, pharmaceutical formulations containing the same, and the use thereof for producing a medicament that is used for the treatment of respiratory diseases, especially COPD (chronic obstructive pulmonary disease) and asthma.
-
2.发明公开
公开(公告)号：EP1326862A1
公开(公告)日：2003-07-16
申请号：EP01983510.7
申请日：2001-09-28
发明人： BANHOLZER, Rolf , SIEGER, Peter , KULINNA, Christian , TRUNK, Michael , GRAULICH, Manfred, Ludwig, August , SPECHT, Peter , MEISSNER, Helmut , MATHES, Andreas
IPC分类号： C07D451/10 , A61K31/46 , A61P43/00
CPC分类号： C07D451/10
摘要： The invention relates to a crystalline monohydrate of (1α,2β,4β,5α,7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatrycyclo[3.3.1.02,4]nonane bromide, to a method for producing the same, and to the use thereof in the production of a medicament, especially for producing a medicament that has an anticholinergic effect.
-
3.发明授权
公开(公告)号：EP1326862B1
公开(公告)日：2004-09-15
申请号：EP01983510.7
申请日：2001-09-28
发明人： BANHOLZER, Rolf , SIEGER, Peter , KULINNA, Christian , TRUNK, Michael , GRAULICH, Manfred, Ludwig, August , SPECHT, Peter , MEISSNER, Helmut , MATHES, Andreas
IPC分类号： C07D451/10 , A61K31/46 , A61P43/00
CPC分类号： C07D451/10
摘要： The invention relates to a crystalline monohydrate of (1α,2β,4β,5α,7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatrycyclo[3.3.1.02,4]nonane bromide, to a method for producing the same, and to the use thereof in the production of a medicament, especially for producing a medicament that has an anticholinergic effect.
摘要翻译： 噻托溴铵（（1α的，2beta，4beta，将5α-，7beta）-7-（2-羟基-2,2-二（2-噻吩基）乙酰氧基）-9,9-二甲基-3-氧杂的结晶一水合物（I） -9-氮鎓三环[3.3.1.0 2> 0.4]壬烷溴化物）是新的。 因此独立claimsoft包括用于制备（I）。 活动：消炎; 平喘。 作用机制：抗胆碱。
-
4.发明公开
公开(公告)号：EP1682543A1
公开(公告)日：2006-07-26
申请号：EP04791030.2
申请日：2004-10-29
IPC分类号： C07D451/10 , A61K31/46 , A61P11/00
CPC分类号： C07D451/10
摘要： The invention relates to novel tiotropium salts, methods for the production thereof, pharmaceutical formulations containing the same, and the use thereof for producing a medicament that is used for the treatment of respiratory diseases, especially COPD (chronic obstructive pulmonary disease) and asthma.
-
5.发明授权
公开(公告)号：EP1325001B1
公开(公告)日：2004-02-18
申请号：EP01982374.9
申请日：2001-09-28
发明人： MEISSNER, Helmut , MORSCHHÄUSER, Gerd , PIEPER, Michael, Paul , POHL, Gerald , REICHL, Richard , SPECK, Georg , BANHOLZER, Rolf
IPC分类号： C07D451/10 , A61K31/46 , A61P43/00
CPC分类号： C07D451/10
摘要： The invention relates to novel anticholinergic agents of general formula (1), wherein A, X- and radicals R?1, R2, R3, R4, R5, R6 and R7¿ can have the meanings as cited in the claims and in the description. The invention also relates to the use of these agents as medicaments.
-
6.发明公开
公开(公告)号：EP1325001A1
公开(公告)日：2003-07-09
申请号：EP01982374.9
申请日：2001-09-28
发明人： MEISSNER, Helmut , MORSCHHÄUSER, Gerd , PIEPER, Michael, Paul , POHL, Gerald , REICHL, Richard , SPECK, Georg , BANHOLZER, Rolf
IPC分类号： C07D451/10 , A61K31/46 , A61P43/00
CPC分类号： C07D451/10
摘要： The invention relates to novel anticholinergic agents of general formula (1), wherein A, X- and radicals R?1, R2, R3, R4, R5, R6 and R7¿ can have the meanings as cited in the claims and in the description. The invention also relates to the use of these agents as medicaments.
-
7.发明授权
公开(公告)号：EP0579615B1
公开(公告)日：2001-07-04
申请号：EP92905643.0
申请日：1992-03-05
发明人： BANHOLZER, Rolf , BAUER, Rudolf , REICHL, Richard
IPC分类号： C07D451/10 , C07D451/14 , A61K31/46
CPC分类号： C07D451/10 , C07D451/14
-
8.发明公开
公开(公告)号：EP1682541A1
公开(公告)日：2006-07-26
申请号：EP04791028.6
申请日：2004-10-29
IPC分类号： C07D451/10 , A61K31/46 , A61P11/00
CPC分类号： C07D451/10 , C07D451/06
摘要： The invention provides a method for producing novel tiotropium salts of formula (I), wherein X- represents an anion, said novel tiotropium salts as such, pharmaceutical formulations, containing the salts and the use thereof for producing a medicament for the treatment of respiratory tract diseases, in particular, for the treatment of chronic obstructive pulmonary disease (COPD) and asthma.
-
9.发明授权ARZNEIMITTELVORBEREITUNGEN ENTHALTEND EIN ENANTIOMER VON IPRATROPIUMBROMID MIT VERLÄNGERTER WIRKUNGSDAUER 失效DRUGS PREPARATIONS含异丙托溴铵的对映体延长的持续时间的影响
公开(公告)号：EP0843676B1
公开(公告)日：2001-11-07
申请号：EP96927638.5
申请日：1996-07-31
发明人： BANHOLZER, Rolf , REICHL, Richard , DISSE, Bernd , SPECK, Georg
IPC分类号： C07D451/10 , A61K31/46
CPC分类号： C07D451/10
摘要： The invention concerns the use of the salts of the L-(-)-enantiomer of (endo, syn)-(-)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(methylethyl)-8-azoniabicyclo[3.2.1] octane as active substances for medicaments administered by inhalation for treatment of the respiratory tract. These salts are suitable for such treatment owing to their unexpectedly intense and prolonged effect.
-
10.发明公开
公开(公告)号：EP0579615A1
公开(公告)日：1994-01-26
申请号：EP92905643.0
申请日：1992-03-05
发明人： BANHOLZER, Rolf , BAUER, Rudolf , REICHL, Richard
CPC分类号： C07D451/10 , C07D451/14
摘要： De nouveaux composés répondant à la formule (I): AO-CO-Z, dans laquelle A et Z ont la signification donnée dans la description, peuvent être préparés selon des méthodes classiques; ils sont utiles comme substances actives dans des médicaments.
-
-
-
-
-
-
-
-
-
搜索结果
14 条记录 (耗时 0.019 秒)
