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公开(公告)号：EP0886637B1
公开(公告)日：2004-12-01
申请号：EP96903604.5
申请日：1996-02-01
发明人： WETTERAU, John, R. II , SHARP, Daru, Young , GREGG, Richard, E. , BILLER, Scott, A. , DICKSON, John, A. , LAWRENCE, R., Michael , MAGNIN, David, R. , POSS, Michael, A. , ROBL, Jeffrey, A. , SULSKY, Richard, B. , TINO, Joseph, A. , LAWSON, John, E. , HOLAVA, Henry, M. , PARTYKA, Richard, A.
IPC分类号： C07D401/04 , C07D401/06 , C07D401/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/12 , C07D211/58 , A61K31/445
CPC分类号： C07D401/04 , C07D211/58 , C07D211/60 , C07D211/94 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D419/12 , G01N2800/044
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2.发明公开MTP INHIBITORS AND FAT SOLUBLE VITAMIN THERAPEUTIC COMBINATIONS TO LOWER SERUM LIPID LEVELS 失效MTP抑制剂和脂溶性维生素疗法，降低血脂
公开(公告)号：EP1024804A1
公开(公告)日：2000-08-09
申请号：EP98918680.4
申请日：1998-04-23
IPC分类号： A61K31/355 , A61K31/34 , A61K31/075 , A61K31/445 , A61K31/495 , A61K31/50
摘要： A pharmaceutical combination formed of an MTP inhibitor and a fat soluble vitamin such as Vitamins E, A, K and/or D, and optionally another cholesterol lowering drug, is provided which is employed in a method for lowering serum lipids, cholesterol and/or triglycerides and thereby inhibiting or treating atherosclerosis, pancreatitis, hyperglycemia and/or obesity.
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公开(公告)号：EP0886637B9
公开(公告)日：2005-05-04
申请号：EP96903604.5
申请日：1996-02-01
发明人： WETTERAU, John, R. II , SHARP, Daru, Young , GREGG, Richard, E. , BILLER, Scott, A. , DICKSON, John, A. , LAWRENCE, R., Michael , MAGNIN, David, R. , POSS, Michael, A. , ROBL, Jeffrey, A. , SULSKY, Richard, B. , TINO, Joseph, A. , LAWSON, John, E. , HOLAVA, Henry, M. , PARTYKA, Richard, A.
IPC分类号： C07D401/04 , C07D401/06 , C07D401/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/12 , C07D211/58 , A61K31/445
CPC分类号： C07D401/04 , C07D211/58 , C07D211/60 , C07D211/94 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D419/12 , G01N2800/044
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4.发明公开METHOD FOR LOWERING SERUM LIPID LEVELS EMPLOYING AN MTP INHIBITOR IN COMBINATION WITH ANOTHER CHOLESTEROL LOWERING DRUG 失效PROCESS FOR血脂水平镜的羞辱USING A的MTP抑制剂与另一种ACTIVE CHOLESTERINERNIEDRIGENDEN
公开(公告)号：EP1014791A1
公开(公告)日：2000-07-05
申请号：EP97933435.6
申请日：1997-07-14
CPC分类号： A61K45/06 , A61K31/19 , A61K31/195 , A61K31/215 , A61K31/365 , A61K31/40 , A61K31/405 , A61K31/455 , A61K31/60 , A61K31/70 , A61K31/785 , Y10S514/824
摘要： A method is provided for lowering serum lipids, cholesterol and/or triglycerides and thereby inhibiting atherosclerosis by administering to a patient an MTP inhibitor, in combination with a cholesterol lowering drug, such as pravastatin.
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