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1.发明授权IVIG MODULATION OF CHEMOKINES FOR TREATMENT OF MULTIPLE SCLEROSIS, ALZHEIMER'S DISEASE, AND PARKINSON'S DISEASE 有权趋化因子的IVIG调制多发性硬化症的治疗，老年痴呆症和帕金森氏症
公开(公告)号：EP2191014B1
公开(公告)日：2013-04-03
申请号：EP08785488.1
申请日：2008-08-11
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
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2.发明授权
公开(公告)号：EP2257804B1
公开(公告)日：2013-12-11
申请号：EP09718006.1
申请日：2009-02-25
CPC分类号： G01N33/5014 , G01N33/5008 , G01N33/5058 , G01N33/6896 , G01N2333/4709 , G01N2500/10
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3.发明公开
公开(公告)号：EP2257804A1
公开(公告)日：2010-12-08
申请号：EP09718006.1
申请日：2009-02-25
CPC分类号： G01N33/5014 , G01N33/5008 , G01N33/5058 , G01N33/6896 , G01N2333/4709 , G01N2500/10
摘要： The present invention relates to a cell-based in vitro screening assay for identifying and selecting therapeutic agents that inhibit amyloid β-induced cytotoxicity.
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4.发明公开
公开(公告)号：EP2235188A2
公开(公告)日：2010-10-06
申请号：EP08870385.5
申请日：2008-12-30
发明人： SASGARY, Maria , SCHUSTER, Maria , SCHWARZ, Hans-Peter , REIPERT, Birgit , ANTOINE, Gerhard , EHRLICH, Hartmut
IPC分类号： C12N15/85 , A01K67/027 , C07K14/745 , C07K14/755 , A61K49/00 , G01N33/50 , C12N9/64
CPC分类号： C12N15/8509 , A01K67/0275 , A01K2207/15 , A01K2217/00 , A01K2217/15 , A01K2227/105 , A01K2267/02 , A01K2267/03 , C07K14/745 , C07K14/755 , C12N9/64
摘要： The present invention relates, in general, to development of non-human transgenic animals expressing a human blood clotting factor, such as Factor VIII, Factor VII, Factor IX and von Willebrand factor. The invention further provides methods of detecting immunogenic events against human blood clotting factor using the transgenic animals described.
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5.发明公开IVIG MODULATION OF CHEMOKINES FOR TREATMENT OF MULTIPLE SCLEROSIS, ALZHEIMER'S DISEASE, AND PARKINSON'S DISEASE 有权趋化因子的IVIG调制多发性硬化症的治疗，老年痴呆症和帕金森氏症
公开(公告)号：EP2191014A2
公开(公告)日：2010-06-02
申请号：EP08785488.1
申请日：2008-08-11
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要： The present invention provides methods for providing a prognosis of treatment of diseases associated with inflammatory disease of the brain, including MS, e.g., relapsing- remitting multiple sclerosis (RRMS), Alzheimer's disease, and Parkinson's disease using molecular markers that are shown to be overexpressed or underexpressed in patients treated with intravenous immunoglobulins (IVIG). Also provided are methods to identify compounds that are useful for the treatment or prevention of MS, e.g., relapsing-remitting multiple sclerosis (RRMS), Alzheimer's disease, and Parkinson's disease.
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6.发明公开CHARACTERIZATION OF SUBVISIBLE PARTICLES USING A PARTICLE ANALYZER 审中-公开CHARAKTERISIERUNG VON SUBVISIBLEN TEILCHEN MIT EINEM TEILCHENANALYSATOR
公开(公告)号：EP2802871A2
公开(公告)日：2014-11-19
申请号：EP13703486.4
申请日：2013-01-11
IPC分类号： G01N33/483 , G01N15/10 , G01N33/68
CPC分类号： G01N33/6839 , C12Q1/56 , G01N15/1012 , G01N15/1429 , G01N33/48735 , G01N33/6803 , G01N33/86 , G01N2015/1493
摘要： The present specification discloses methods of characterizing a population of particles using a particle analyzer. Particles may be characterized by size, absolute number, whether the particle is non-proteinaceous or proteinaceous, whether a proteinaceous particle has or lacks a certain physical property, or any combination thereof.
摘要翻译： 本说明书公开了使用粒子分析仪表征粒子群体的方法。 颗粒的尺寸，绝对数量，颗粒是否为非蛋白质或蛋白质，蛋白质颗粒是否具有或缺乏一定的物理性质，或其任何组合的特征。
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