公开(公告)号：EP1296962B1

公开(公告)日：2007-09-05

申请号：EP01960270.5

申请日：2001-06-05

申请人： Bayer CropScience AG

发明人： BEIER, Christian ,  LANTZSCH, Reinhard

IPC分类号： C07D249/14

CPC分类号： C07D249/14

摘要： The invention relates to a method for preparing 5-amino-N-phenyl-1,2,4-triazole-3-sulfonamides of general formula (I). The inventive method is characterized in that 5-amino-3-chlorosulfonyl-1,2,4-triazole of formula (II) is reacted, in the presence of a solvent, with substituted anilines of general formula (III), in which X, n and R have the above-mentioned meanings.

公开(公告)号：EP1021420B1

公开(公告)日：2003-03-26

申请号：EP98958843.9

申请日：1998-09-25

申请人： Bayer CropScience AG

发明人： LANTZSCH, Reinhard ,  JAUTELAT, Manfred ,  HUPPERTS, Achim ,  ERDMAN, David

IPC分类号： C07D249/12

CPC分类号： C07D249/12

公开(公告)号：EP1265902A1

公开(公告)日：2002-12-18

申请号：EP01916951.5

申请日：2001-01-25

申请人： Bayer CropScience AG

发明人： WEINTRITT, Holger ,  LANTZSCH, Reinhard ,  MÜH, Thorsten

IPC分类号： C07D491/04 ,  C07D413/12

CPC分类号： C07D413/12 ,  C07D491/04

摘要： A method for producing sulfonyl imidazole derivatives of formula (I), wherein R, R1, R2 and X have the meanings cited in the description. Imidazole derivatives of formula (II) are reacted with sulfonyl chlorides of formula (III) in the presence of an acid binder, an organic diluent which is only slightly mixable with water, water and a phase transfer catalyst.

公开(公告)号：EP0904268B1

公开(公告)日：2002-12-04

申请号：EP97923924.1

申请日：1997-05-16

申请人： Bayer CropScience AG

发明人： GAYER, Herbert ,  GALLENKAMP, Bernd ,  GERDES, Peter ,  HEINEMANN, Ulrich ,  KRÜGER, Bernd-Wieland ,  LANTZSCH, Reinhard ,  SEITZ, Thomas ,  STELZER, Uwe

IPC分类号： C07D273/00 ,  C07D307/82 ,  C07D307/83

CPC分类号： C07D273/00 ,  C07D307/82 ,  C07D307/83 ,  C07D407/12

公开(公告)号：EP1678119B1

公开(公告)日：2011-01-05

申请号：EP04790277.0

申请日：2004-10-12

申请人： Bayer CropScience AG

发明人： LANTZSCH, Reinhard ,  JÖRGES, Wolfgang ,  PAZENOK, Sergiy

IPC分类号： C07C229/36 ,  C07D231/14

CPC分类号： C07C229/30 ,  C07D231/14

摘要： The invention relates to a method for producing 2-dihaloacyl-3-amino-acrylic acid esters of formula (I). Said method is characterised in that acid halides of formula (II) are reacted with dialkyl amino-acrylic acid esters of formula (III), in which R, R1, R2, X1, X2 and Hal are defined as cited in the description, in a water-immiscible organic solvent in the presence of a base. The invention also relates to the novel 2-dihaloacyl-3-amino-acrylic acid esters of formula (I), to their use for producing 3-dihalomethyl-pyrazoles, to a method for producing 3-dihalomethyl-pyrazoles, in addition to novel 3-dihalomethyl-pyrazoles.

公开(公告)号：EP0970052B1

公开(公告)日：2004-08-11

申请号：EP98912427.6

申请日：1998-03-02

申请人： Bayer CropScience AG

发明人： LANTZSCH, Reinhard ,  STELZER, Uwe

IPC分类号： C07D213/61 ,  C07D213/38 ,  C07B43/04

CPC分类号： C07D213/38 ,  C07D213/61

公开(公告)号：EP1417168A2

公开(公告)日：2004-05-12

申请号：EP02758383.0

申请日：2002-07-24

申请人： Bayer CropScience AG

发明人： WEINTRITT, Holger ,  LANTZSCH, Reinhard ,  MÜH, Thorsten

IPC分类号： C07C249/08 ,  C07C251/48 ,  C07C249/04

CPC分类号： C07C249/04 ,  C07C251/48

摘要： The invention relates to a novel method for producing 2-(hydroxyphenyl)-2-(alkoxyimino)-N-methylacetamide derivatives.

公开(公告)号：EP1003718B1

公开(公告)日：2004-04-28

申请号：EP98940212.8

申请日：1998-07-13

申请人： Bayer CropScience AG

发明人： HUPPERTS, Achim ,  DREWES, Mark, Wilhelm ,  ERDMAN, David ,  LANTZSCH, Reinhard

IPC分类号： C07C303/38 ,  C07C303/40 ,  C07C211/52 ,  C07C311/08 ,  C07C311/48

CPC分类号： C07C311/08 ,  C07C255/58 ,  C07C303/38 ,  C07C303/40 ,  C07C311/48

摘要： The invention relates to a method for producing N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides. In a first step, 2-amino-4,5-difluoro-benzonitrile is reacted with sulphonic acid halogenides in the presence of an acid acceptor and a diluting agent at temperatures between 0 °C and 150 °C. In a second step, the N-(2-cyano-4,5-difluoro-phenyl)-sulphonamide and/or N-(2-cyano-4,5-difluoro-phenyl)-sulphonamides are reacted, either in the pure state or mixed, with ammonia in the presence of a diluting agent at temperatures between 100 °C and 200 °C. The invention also relates to new intermediate products of this method.

摘要翻译： 本发明涉及生产N-（5-氨基-2-氰基-4-氟 - 苯基） - 磺酰胺的方法。 在第一步中，2-氨基-4,5-二氟 - 苯甲腈与磺酸卤化物在酸受体和稀释剂存在下在0℃至150℃之间的温度下反应。 在第二步中，将N-（2-氰基-4,5-二氟 - 苯基） - 磺酰胺和/或N-（2-氰基-4,5-二氟 - 苯基） - 磺酰胺以纯 在稀释剂存在下，在100℃和200℃之间的温度下与氨一起混合或混合。 本发明还涉及该方法的新的中间产物。

公开(公告)号：EP1030846B1

公开(公告)日：2003-07-16

申请号：EP98959829.7

申请日：1998-11-03

申请人： Bayer CropScience AG

发明人： GALLENKAMP, Bernd ,  LANTZSCH, Reinhard ,  ROHE, Lothar ,  MULDER, Lubbertus

IPC分类号： C07D239/54 ,  C07D239/46 ,  C07C275/24 ,  C07C275/16

CPC分类号： C07D239/47 ,  C07C275/16 ,  C07C275/24 ,  C07D239/54 ,  C07D239/553

公开(公告)号：EP1045829B1

公开(公告)日：2003-06-04

申请号：EP98966672.2

申请日：1998-12-24

申请人： Bayer CropScience AG

发明人： HUPPERTS, Achim ,  LANTZSCH, Reinhard

IPC分类号： C07C231/02 ,  C07C233/43 ,  C07C235/56 ,  C07C269/04 ,  C07C271/28 ,  C07C303/38 ,  C07C311/08

CPC分类号： C07C231/02 ,  C07C269/04 ,  C07C303/38 ,  C07C311/08 ,  C07C233/80 ,  C07C235/56 ,  C07C271/26

摘要： The invention relates to a method for producing N-(3-amino-4-fluorophenyl)- sulphonamides, N-(3-amino-4-fluorophenyl) carboxylic acid amides and N-(3-amino-4-fluorophenyl) carbamates of general formula (I), wherein A stands for SO2, CO or CO2 and R stands for optionally substituted alkyl or aryl, whereby 1-fluoro-2,4 diamino-benzol of formula (II) with sulphonyl chlorides, carboxylic acid chlorides or chloroformic acid esters of general formula (III), wherein A and R have the meaning cited above, is made to react with an acid acceptor and in the presence of a diluting agent at temperatures ranging between -20 °C and +100 °C.