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12 条记录 (耗时 0.014 秒)

    COMPACT BLOOD CULTURE APPARATUS
    4.
    发明授权
    COMPACT BLOOD CULTURE APPARATUS 失效
    紧凑的设备对文化的血液

    公开(公告)号：EP0773988B1

    公开(公告)日：2002-10-02

    申请号：EP96920326.4

    申请日：1996-05-21

    申请人： Becton Dickinson and Company

    发明人： SCHWARZ, Daniel, L. ,  BERNDT, Klaus, W.

    IPC分类号： C12M1/34 ,  G01N35/02

    CPC分类号： G01N21/253 ,  C12M23/08 ,  C12M27/10 ,  C12M41/14 ,  C12M41/36 ,  G01N35/025 ,  G01N2035/00306 ,  G01N2035/00752 ,  G01N2035/0458 ,  Y10S435/801 ,  Y10S435/808 ,  Y10S435/809

    摘要： The present invention describes an apparatus (1) for detecting biological activities in a large number of blood culture containers (20). The containers are placed in a plurality of wells (35) arranged in concentric rows (36, 37, 38) on a turntable that is rotated about a central axis. Each well is designed to receive and hold one of a plurality of sealable containers inserted base first, with each container having optical sensing means for sensing microorganisms therein and a bar code pattern attached thereto for identification purposes. Each well has an opening (39) in its base (40) to allow a sensor station to monitor a fluorescence chemical sensor (27) in each container to determine whether there is microorganism growth within the container. Prior to inserting each container into a well on the turntable, a culture medium and blood specimen are introduced into the container and the bar code is scanned to identify the container. As the containers are rotated on the turntable they are exposed to conditions enabling a variety of metabolic, physical, and chemical changes to take place in the presence of microorganisms within the specimen. The apparatus also includes a door on the front that opens and permits the turntable to be loaded and unloaded from the front of the apparatus with simultaneous access to all containers.

    METHOD AND APPARATUS FOR DETERMINING DISPENSE VOLUME
    5.
    发明公开
    METHOD AND APPARATUS FOR DETERMINING DISPENSE VOLUME 有权
    VERFAHREN UND VORRICHTUNG ZUR BESTIMMUNG EINES ABGABEVOLUMENS

    公开(公告)号：EP2147317A1

    公开(公告)日：2010-01-27

    申请号：EP08746221.4

    申请日：2008-04-18

    申请人： Becton, Dickinson and Company

    发明人： BERNDT, Klaus, W.

    IPC分类号： G01N35/10

    CPC分类号： G01N35/1016

    摘要： In needle-based dispensing systems, the target amount of liquid to be dispensed is in many cases very well controlled. However, the amount of liquid that is actually reaching the receiving well may show a discrepancy, because part of the liquid leaving the inner needle space remains on the outer surface of the dispense needle, and so a small amount of liquid is “lost” in the dispensing act. A sensor arrangement according to the present invention is suitable for detecting the presence of any liquid from the aspiration reservoir that is left behind on the outside of the dispense needle, before the dispense step is actually started. The “lost” volume can also be measured very accurately by inserting the tip of a dispense needle into a hollow metallic cylinder, forming a capacitor, whereby the capacitance value depends on the volume of the “lost” dispense volume.

    摘要翻译： 在基于针的分配系统中，待分配的液体的目标量在许多情况下是非常好的控制的。 然而，实际到达接收井的液体量可能显示出差异，因为离开内针空间的液体的一部分留在分配针的外表面上，因此少量的液体“丢失” 分配行为。 根据本发明的传感器装置适用于在分配步骤实际开始之前检测在分配针外侧留下的吸液容器中存在任何液体。 也可以通过将分配针的尖端插入中空的金属圆筒，形成电容器，由此电容值取决于“丢失”分配体积的体积，可以非常精确地测量“丢失”体积。

    FLUORESCENCE DETECTOR
    6.
    发明公开
    FLUORESCENCE DETECTOR 失效
    荧光检测器

    公开(公告)号：EP0850410A1

    公开(公告)日：1998-07-01

    申请号：EP96929654.0

    申请日：1996-08-21

    申请人： Becton, Dickinson and Company

    发明人： BERNDT, Klaus, W.

    IPC分类号： C12M1 ,  G01N21 ,  G01N33

    CPC分类号： G01N21/6408 ,  C12M41/36 ,  Y10S435/808

    摘要： A fluorescence detector method and apparatus for detecting biological activities in a fluid specimen, such as blood, urine or sputum, where the specimen and a culture medium are introduced into sealable containers and exposed to conditions enabling a variety of metabolic, physical, and chemical changes to take place in the presence of microorganisms in the sample. In operation, the detector method and apparatus illuminate a chemical sensor material in the sealable container with excitation light which is turned on and off periodically according to a symmetric square wave, split the measured fluorescence photocurrent into two components that represent different harmonics of the symmetric square wave signal, measure the amplitudes of the two components, generate the ratio of the two components, and use that ratio as the sensor output signal to indicate biological activity.

    COMPACT BLOOD CULTURE APPARATUS
    7.
    发明公开
    COMPACT BLOOD CULTURE APPARATUS 失效
    紧凑的设备对文化的血液

    公开(公告)号：EP0773988A1

    公开(公告)日：1997-05-21

    申请号：EP96920326.0

    申请日：1996-05-21

    申请人： Becton Dickinson and Company

    发明人： SCHWARZ, Daniel, L. ,  BERNDT, Klaus, W.

    IPC分类号： G01N33 ,  C12M1 ,  G01N21 ,  G01N35

    CPC分类号： G01N21/253 ,  C12M23/08 ,  C12M27/10 ,  C12M41/14 ,  C12M41/36 ,  G01N35/025 ,  G01N2035/00306 ,  G01N2035/00752 ,  G01N2035/0458 ,  Y10S435/801 ,  Y10S435/808 ,  Y10S435/809

    摘要： The present invention describes an apparatus (1) for detecting biological activities in a large number of blood culture containers (20). The containers are placed in a plurality of wells (35) arranged in concentric rows (36, 37, 38) on a turntable that is rotated about a central axis. Each well is designed to receive and hold one of a plurality of sealable containers inserted base first, with each container having optical sensing means for sensing microorganisms therein and a bar code pattern attached thereto for identification purposes. Each well has an opening (39) in its base (40) to allow a sensor station to monitor a fluorescence chemical sensor (27) in each container to determine whether there is microorganism growth within the container. Prior to inserting each container into a well on the turntable, a culture medium and blood specimen are introduced into the container and the bar code is scanned to identify the container. As the containers are rotated on the turntable they are exposed to conditions enabling a variety of metabolic, physical, and chemical changes to take place in the presence of microorganisms within the specimen. The apparatus also includes a door on the front that opens and permits the turntable to be loaded and unloaded from the front of the apparatus with simultaneous access to all containers.

    APPARATUS FOR PERFORMING OPTICAL MEASUREMENTS ON BLOOD CULTURE BOTTLES
    8.
    发明公开
    APPARATUS FOR PERFORMING OPTICAL MEASUREMENTS ON BLOOD CULTURE BOTTLES 审中-公开
    DEVICE具体血培养瓶进行光学测量

    公开(公告)号：EP1779094A1

    公开(公告)日：2007-05-02

    申请号：EP05786400.1

    申请日：2005-08-16

    申请人： Becton, Dickinson and Company

    发明人： BERNDT, Klaus, W.

    IPC分类号： G01N21/51 ,  G01N21/90 ,  C12M1/34

    CPC分类号： G01N21/51

    摘要： An apparatus and method for rapidly distinguishing positive blood cultures from negative bloodcultures in sealable containers, and for determining the combination of blood volume and hematocrit in a sealable container. The apparatus comprises an optical source for illuminating the culture with a light beam under an oblique angle to generate an asymmetric spatial distribution of backscattered light, which is imaged onto an imaging detector connected to a data analyzer.

    APPARATUS FOR PERFORMING OPTICAL MEASUREMENTS ON BLOOD CULTURE BOTTLES
    9.
    发明授权
    APPARATUS FOR PERFORMING OPTICAL MEASUREMENTS ON BLOOD CULTURE BOTTLES 有权

    公开(公告)号：EP1779094B1

    公开(公告)日：2018-10-03

    申请号：EP05786400.1

    申请日：2005-08-16

    申请人： Becton, Dickinson and Company

    发明人： BERNDT, Klaus, W.

    IPC分类号： G01N21/51 ,  G01N21/90 ,  C12M1/34

    CPC分类号： G01N21/51

    摘要： An apparatus and method for rapidly distinguishing positive blood cultures from negative bloodcultures in sealable containers, and for determining the combination of blood volume and hematocrit in a sealable container. The apparatus comprises an optical source for illuminating the culture with a light beam under an oblique angle to generate an asymmetric spatial distribution of backscattered light, which is imaged onto an imaging detector connected to a data analyzer.