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    NANOSCALE SENSOR
    2.
    发明公开
    NANOSCALE SENSOR 审中-公开
    传感器IM NANOMASSSTAB

    公开(公告)号：EP1330536A1

    公开(公告)日：2003-07-30

    申请号：EP01979651.5

    申请日：2001-10-10

    申请人： Bioforce Nanosciences, Inc.

    发明人： HENDERSON, Eric ,  MOSHER, Curtis

    IPC分类号： C12Q1/00 ,  C12M1/34 ,  G01N27/26

    CPC分类号： B82Y15/00 ,  C12Q1/001 ,  C12Q1/48 ,  G01N27/041 ,  G01N33/54373 ,  G01N2333/91245

    摘要： In the present invention, organic, inorganic, or other molecules or objects that may participate in an interaction event, are physically linked to nanoscale objects, typified, but not limited to, carbon nanotubes, silicon nanotubes, nanobars, and biological structural elements, such as microtubules and actin filaments, to create a signal transduction system that reports events on the micron scale or smaller. A molecular interaction even is monitored utilizing an amp meter or utilizing a scanning tunneling microscope so that when the molecules or objects participate in a molecule interaction event, or some other interaction event, the movement or change in the physical properties of the nanotube is monitored to report the occurrence of the interaction event.

    EVALUATING BINDING AFFINITIES BY FORCE STRATIFICATION AND FORCE PLANNING
    4.
    发明公开
    EVALUATING BINDING AFFINITIES BY FORCE STRATIFICATION AND FORCE PLANNING 审中-公开
    评价中的结合亲和力BY FORCE BUILD和平移

    公开(公告)号：EP1330651A2

    公开(公告)日：2003-07-30

    申请号：EP01981445.8

    申请日：2001-10-10

    申请人： Bioforce Nanosciences, Inc.

    发明人： HENDERSON, Eric ,  MOSHER, Curtis

    IPC分类号： G01N33/543

    CPC分类号： C07K16/065 ,  Y10S436/807

    摘要： The present invention is a method for selectively removing objects from a surface utilizing a probe. The probe is scanned over the surface utilizing a greater and greater relative amount of force so that a certain number of the objects are removed from the surface. The force required to remove the objects from the surface can be calculated utilizing Hook's law and the spring constant of the probe. After removal of the objects that have a relatively weaker binding affinity with the surface, the remaining objects can be harvested, characterized, and subjected to further study.