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公开(公告)号：EP2988790A1
公开(公告)日：2016-03-02
申请号：EP14730561.9
申请日：2014-04-28
申请人： Biointeractions Ltd.
IPC分类号： A61L27/16 , A61L27/26 , A61L27/34 , A61L27/54 , A61L29/04 , A61L29/08 , A61L29/16 , A61L31/04 , A61L31/10 , A61L31/16 , A61L33/00 , A61L33/06
CPC分类号： A61K31/728 , A61K9/0012 , A61K31/131 , A61K31/14 , A61K31/727 , A61K47/32 , A61L27/16 , A61L27/26 , A61L27/34 , A61L27/54 , A61L29/041 , A61L29/049 , A61L29/085 , A61L29/16 , A61L31/041 , A61L31/048 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L33/064 , A61L2300/206 , A61L2300/208 , A61L2300/236 , A61L2300/404 , A61L2300/42 , A61L2300/44 , A61L2300/45
摘要： Antimicrobial and antithrombogenic polymer or polymeric blend, compounds, coatings, and materials containing the same, as well as articles made with, or coated with the same, and methods of making the same exhibiting improved antimicrobial properties and reduced platelet adhesion. Embodiments include polymers with antimicrobial and antithrombogenic groups bound to a single polymer backbone, an antimicrobial polymer blended with an antithrombogenic polymer, and medical devices coated with the antimicrobial and antithrombogenic polymer or polymeric blend.
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公开(公告)号：EP1401511A2
公开(公告)日：2004-03-31
申请号：EP02751298.7
申请日：2002-06-26
申请人： Biointeractions Ltd
CPC分类号： C08B37/0075 , A61L27/20 , A61L27/34 , A61L27/507 , A61L27/52 , A61L33/0011 , A61L33/0064 , C08B37/0063 , C08B37/0069 , Y10S514/822 , Y10S514/944 , Y10S514/953 , C08L39/06
摘要： The invention includes a medical hydrogel made from polymerized polysaccharide macromers. The macromers are preferably polysaccharides decorated with polymerizable groups, for example, methacrylates. The macromers may also be made into polymers of at least two macromers polymerized together. These polymers are preferably multi-armed or high-molecular weight and used for medical uses, for example, making coatings on medical devices. Macromers of N-vinylpyrrolidone are also disclosed herein.
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公开(公告)号：EP3699220A1
公开(公告)日：2020-08-26
申请号：EP20168956.9
申请日：2014-04-28
申请人： Biointeractions Ltd
IPC分类号： C08G65/332 , C08G65/333 , C09D171/02
摘要： Antimicrobial copolymers and antithrombogenic copolymers are provided, together with compounds, coatings, and materials containing the same, as well as articles made with, or coated with the same, and methods of making the same exhibiting improved antimicrobial properties and reduced platelet adhesion.
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公开(公告)号：EP1175148A1
公开(公告)日：2002-01-30
申请号：EP00925500.1
申请日：2000-04-28
申请人： Biointeractions Ltd
CPC分类号： G02B1/043 , A01N47/44 , A61L27/54 , A61L29/16 , A61L2300/204 , A61L2300/206 , A61L2300/402 , A61L2300/404 , C08F20/60 , C08G18/678 , C08G77/452 , A01N25/34 , A01N25/10 , A01N2300/00
摘要： A family of infection resistant and biocidal polymeric materials incorporates an infection resistant biguanide such as chlorhexidine or polyhexanide pendant to the polymer chain, chemically linked to the polymer through the biguanide group secondary nitrogen atoms. The disclosure extends to the use of such polymeric materials in articles of manufacture and particularly in medical devices, and the preparation of the materials as polymer resins from which articles can be made, as solutions and emulsions which can be used for coating performed articles, and in situ on the surface of preformed polymeric articles.
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公开(公告)号：EP1161268A2
公开(公告)日：2001-12-12
申请号：EP00909499.6
申请日：2000-03-13
申请人： Biointeractions Ltd
IPC分类号： A61L27/00
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/072 , A61F2002/075 , A61F2220/0075 , A61L31/10
摘要： The vascular endoprosthesis comprises an array of cylindrical elements (4) arranged internally or externally and secured (8) to a continuous tubular element (7). This composite device is described as an arrayed stent graft. The cylindrical elements of the arrayed stent graft are constructed of metal or other suitable material, and the tubular element may be either knitted or woven textile, a thin walled polymer tube, a thin walled elastomeric tube or a composite of two or more of these or other compounds. All external surfaces of the arrayed stent graft are composed of biocompatible material consisting of a polymer having both non-thrombogenic and anti-thrombogenic properties on the same polymer backbone or, if required, only non-thrombogenic or only anti-thrombogenic properties as described in WO 97/41164.
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公开(公告)号：EP1161268B1
公开(公告)日：2005-08-31
申请号：EP00909499.6
申请日：2000-03-13
申请人： Biointeractions Ltd
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/072 , A61F2002/075 , A61F2220/0075 , A61L31/10
摘要： The vascular endoprosthesis comprises an array of cylindrical elements (4) arranged internally or externally and secured (8) to a continuous tubular element (7). This composite device is described as an arrayed stent graft. The cylindrical elements of the arrayed stent graft are constructed of metal or other suitable material, and the tubular element may be either knitted or woven textile, a thin walled polymer tube, a thin walled elastomeric tube or a composite of two or more of these or other compounds. All external surfaces of the arrayed stent graft are composed of biocompatible material consisting of a polymer having both non-thrombogenic and anti-thrombogenic properties on the same polymer backbone or, if required, only non-thrombogenic or only anti-thrombogenic properties as described in WO 97/41164.
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7.发明公开METHODS AND CLINICAL DEVICES FOR THE INHIBITION OR PREVENTION OF MAMMALIAN CELL GROWTH 审中-公开方法和哺乳动物生长的抑制医疗用品
公开(公告)号：EP1408942A1
公开(公告)日：2004-04-21
申请号：EP02700428.2
申请日：2002-02-15
申请人： Biointeractions Ltd
CPC分类号： A61K31/785 , A61K31/155 , A61L2/16 , A61L27/34 , A61L27/54 , A61L31/10 , A61L31/16 , A61L2300/206 , A61L2300/416 , A61L2300/606
摘要： Mammalian cell growth may be inhibited by use of a chemical material containing at least one biguanide group -NH-C(NH)-NH-C(NH)-NH- in the preparation of a medicament or medical device for the inhibition of mammalian cell growth. The chemical material may be monomeric or polymeric.
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公开(公告)号：EP1175148B1
公开(公告)日：2003-03-19
申请号：EP00925500.1
申请日：2000-04-28
申请人： Biointeractions Ltd
CPC分类号： G02B1/043 , A01N47/44 , A61L27/54 , A61L29/16 , A61L2300/204 , A61L2300/206 , A61L2300/402 , A61L2300/404 , C08F20/60 , C08G18/678 , C08G77/452 , A01N25/34 , A01N25/10 , A01N2300/00
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