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1.发明授权
公开(公告)号：EP0934288B1
公开(公告)日：2006-01-04
申请号：EP97911227.3
申请日：1997-10-15
发明人： BRENNER, Michael , MAIER, Roland , WIENRICH, Marion , WEISER, Thomas , PALLUK, Rainer , BECHTEL, Wolf-Dietrich , SAGRADA, Angelo , ENSINGER, Helmut , PSCHORN, Uwe , CESANA, Raffaele
IPC分类号： C07D271/06 , C07D413/04 , C07D413/12 , C07D451/06 , C07D471/08 , A61K31/41 , C07D221/00 , C07D209/00
CPC分类号： C07D271/06 , C07D413/04
摘要： The invention concerns oxadiazole derivatives of general formula (I) in which X, Y, Z and R1 have the definitions given in the description and the claims. The invention further concerns processes for preparing these substances and their use as medicaments.
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2.发明授权SUBSTITUIERTE 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCINE UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权取代1,2,3,4,5,6六氢-2,6-亚甲基-3- benzazocines及其作为药物
公开(公告)号：EP1235809B1
公开(公告)日：2003-11-12
申请号：EP00993781.4
申请日：2000-11-21
发明人： GRAUERT, Matthias , CARTER, Adrian , WEISER, Thomas , ENSINGER, Helmut , GAIDA, Wolfram , MIERAU, Joachim
IPC分类号： C07D221/26 , C07D221/22 , C07D407/06 , A61K31/445
CPC分类号： C07D405/06 , C07D221/26
摘要： The invention relates to substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines of the general formula (1), wherein the groups R?1, R2, R3, R3', R4, R5, R6¿, X and A are defined as per the description and claims, to a method for their production and to the use thereof as medicaments.
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3.发明公开N-ALLYLOXYETHYL-1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCINE UND IHRE VERWENDUNG ALS ARZNEIMITTEL 审中-公开的N-烯丙氧基-1,2,3,4,5,6-六氢-2,6-亚甲基-3- benzazocines及其作为药物
公开(公告)号：EP1474398A1
公开(公告)日：2004-11-10
申请号：EP03737261.2
申请日：2003-01-21
发明人： CARTER, Adrian , ENSINGER, Helmut , GRAUERT, Matthias , STILLER, Detlef, Andre , WEISER, Thomas
IPC分类号： C07D221/26 , A61K31/439 , A61P9/00 , A61P25/00
CPC分类号： C07D401/14 , C07D221/26 , C07D405/14 , C07D413/14 , C07D417/14
摘要： The invention relates to 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols of general formula (1) wherein the radicals R1, R2, R3, R4, R5, R6, R7, R8 and R9 can have the designations cited in the description and in the claims. The invention also relates to methods for the production thereof and to the use of the same as pharmaceuticals.
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4.发明授权
公开(公告)号：EP1154983B1
公开(公告)日：2004-04-28
申请号：EP00907556.5
申请日：2000-02-12
发明人： STRANSKY, Werner , GRAUERT, Matthias , CARTER, Adrian , WEISER, Thomas , BECHTEL, Wolf-Dietrich , ENSINGER, Helmut , LOTZ, Ralf, Richard, Hermann , PALLUK, Rainer , PSCHORN, Uwe
IPC分类号： C07C217/48 , C07D295/08 , C07D307/52 , C07D309/14 , C07D233/48 , A61K31/138 , A61K31/4453 , A61P9/06 , A61P25/28
CPC分类号： C07D295/088 , C07C217/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2603/66 , C07D233/48 , C07D307/52 , C07D309/14
摘要： The invention relates to novel substituted 3-phenoxy or 3-phenylalkyloxy-2-phenyl-propylamines of general formula (1), to methods for producing them and to their use as medicaments.
摘要翻译： 本发明涉及通式（1）的新型取代的3-苯氧基或3-苯基烷氧基-2-苯基 - 丙胺，其制备方法和用作药物。
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5.发明公开UNSYMMETRISCH SUBSTITUIERTE XANTHINE MIT ADENOSINANTAGONISTISCHEN EIGENSCHAFTEN 失效不平衡取代的黄嘌呤ADENOSINANTAGONISTISCHEN性能。
公开(公告)号：EP0654033A1
公开(公告)日：1995-05-24
申请号：EP93917743.0
申请日：1993-08-05
发明人： KÜFNER-MÜHL, Ulrike , ENSINGER, Helmut , MIERAU, Joachim , KUHN, Franz, Josef , LEHR, Erich , MÜLLER, Enzio
CPC分类号： C07D473/06
摘要： New xanthine derivatives, a process for preparing the same and their use as medicaments are disclosed, as well as their use as intermediate compounds.
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6.发明公开
公开(公告)号：EP0934288A1
公开(公告)日：1999-08-11
申请号：EP97911227.0
申请日：1997-10-15
发明人： BRENNER, Michael , MAIER, Roland , WIENRICH, Marion , WEISER, Thomas , PALLUK, Rainer , BECHTEL, Wolf-Dietrich , SAGRADA, Angelo , ENSINGER, Helmut , PSCHORN, Uwe , CESANA, Raffaele
CPC分类号： C07D271/06 , C07D413/04
摘要： The invention concerns oxadiazole derivatives of general formula (I) in which X, Y, Z and R1 have the definitions given in the description and the claims. The invention further concerns processes for preparing these substances and their use as medicaments.
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公开(公告)号：EP0487673A1
公开(公告)日：1992-06-03
申请号：EP91910772.0
申请日：1991-06-19
发明人： KÜFNER-MÜHL, Ulrike , STRANSKY, Werner , WEBER, Karl-Heinz , ENSINGER, Helmut , KUHN, Franz, Josef , SCHINGNITZ, Günter , LEHR, Erich
CPC分类号： C07D473/06 , F05C2201/021
摘要： Nouveaux dérivés de xanthine ayant la formule (I), leur procédé de production et leur utilisation comme médicaments.
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