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1.发明公开A NOVEL CONCEPT TO REDUCE LEFT ATRIAL PRESSURE IN SYSTOLIC AND DIASTOLIC HF PATIENTS TO TREAT PULMONARY EDEMA AND REDUCE HOSPITALIZATION RATES 审中-公开一种新的概念，用于降低体循环和阵发性HF患者的左心房压力，以治疗肺水肿并降低住院率
公开(公告)号：EP3253297A1
公开(公告)日：2017-12-13
申请号：EP16713136.6
申请日：2016-02-04
发明人： ANAND, Umang , GOEL, Raghav , MCGOWAN, Roger , ROSS, Daniel , HAVERKOST, Patrick , BYRON, Mary , WULFMAN, David R. , ROHL, James , POLLAK, Peter M. , OLSON, Lyle , BEHFAR, Atta , BRUCE, Charles
CPC分类号： A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , A61F2/24 , A61F2210/0014 , A61F2230/0069
摘要： Devices provided herein can include implantable transseptal flow control components adapted to be implanted in an opening in a septal wall. In a closed configuration, the implantable transseptal flow control components provided herein prevent blood from flowing through the opening. In an open configuration, the implantable transseptal flow control components provided herein allow blood to flow from the left atrium to the right atrium. In a closed configuration, implantable transseptal flow control components provided herein can be configured such that blood does not stagnate at a location proximate to a left atrium flow control component side when the pressure differential is below a second predetermined threshold pressure value. Implantable transseptal flow control components provided herein can remain in a closed configuration when a pressure differential between the left atrium and the right atrium is less than a first non-zero predetermined threshold pressure value.
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公开(公告)号：EP1786471B1
公开(公告)日：2015-02-11
申请号：EP05777528.0
申请日：2005-07-29
发明人： TERZIC, Andre , BEHFAR, Atta
CPC分类号： A61K38/30 , A61K35/545 , A61K38/1825 , A61K38/1841 , A61K38/1875 , A61K38/204 , A61K38/2093 , A61K38/4833 , A61K2300/00
摘要： This document provides methods and materials for treating cardiovascular tissue. For example, stem cells, compositions containing stem cells, methods for obtaining stem cells, compositions for generating stem cells expressing particular markers, and methods for repairing cardiovascular tissue arc provided.
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公开(公告)号：EP4433027A1
公开(公告)日：2024-09-25
申请号：EP22896432.6
申请日：2022-11-16
发明人： BEHFAR, Atta , ZHAO, Chunfeng D.
CPC分类号： A61K47/42 , A61P19/02 , A61K35/12 , A61L27/54 , A61K9/06 , A61L2300/3020130101 , A61L2300/41220130101 , A61L27/225 , A61L27/24 , A61L2430/1020130101
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公开(公告)号：EP2303310A2
公开(公告)日：2011-04-06
申请号：EP09763198.0
申请日：2009-05-20
发明人： TERZIC, Andre , BEHFAR, Atta
CPC分类号： C12N5/0657 , A61K31/505 , A61K31/529 , A61K35/28 , A61K35/34 , A61K38/1825 , A61K38/1841 , A61K38/1866 , A61K38/1875 , A61K38/19 , A61K38/22 , A61K38/30 , A61K38/4833 , C12N2501/105 , C12N2501/115 , C12N2501/15 , C12N2501/155 , C12N2501/16 , C12N2501/175 , C12N2501/70 , C12N2501/734 , C12N2501/999 , C12N2506/1353 , A61K2300/00
摘要： This document relates to compositions containing cardiogenic factors, to methods to obtain cells by culturing initial cells in the presence of such factors; and methods of administering the obtained cells to heart tissue.
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公开(公告)号：EP1786471A2
公开(公告)日：2007-05-23
申请号：EP05777528.0
申请日：2005-07-29
发明人： TERZIC, Andre , BEHFAR, Atta
IPC分类号： A61K48/00
CPC分类号： A61K38/30 , A61K35/545 , A61K38/1825 , A61K38/1841 , A61K38/1875 , A61K38/204 , A61K38/2093 , A61K38/4833 , A61K2300/00
摘要： This document provides methods and materials for treating cardiovascular tissue. For example, stem cells, compositions containing stem cells, methods for obtaining stem cells, compositions for generating stem cells expressing particular markers, and methods for repairing cardiovascular tissue arc provided.
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公开(公告)号：EP4440583A1
公开(公告)日：2024-10-09
申请号：EP22912266.8
申请日：2022-12-01
发明人： BEHFAR, Atta , TRABUCO, Emanuel C.
CPC分类号： A61K35/19
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公开(公告)号：EP4244384A1
公开(公告)日：2023-09-20
申请号：EP21892693.9
申请日：2021-11-10
发明人： TERZIC, Andre , BEHFAR, Atta
IPC分类号： C12Q1/6827 , C12Q1/6883
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公开(公告)号：EP3826603A1
公开(公告)日：2021-06-02
申请号：EP19841549.9
申请日：2019-07-24
申请人： Mayo Foundation for Medical Education and Research , Sabbah, Michael , Behfar, Atta , Livia, Christopher , Peterson, Timothy
IPC分类号： A61K8/11 , A61K8/14 , A61K8/98 , A61K9/50 , A61K31/7088 , A61K31/713
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公开(公告)号：EP3723773A1
公开(公告)日：2020-10-21
申请号：EP18889223.6
申请日：2018-12-14
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公开(公告)号：EP2433125B1
公开(公告)日：2018-11-28
申请号：EP10721224.3
申请日：2010-05-20
IPC分类号： G01N33/50
CPC分类号： C12N5/0657 , A61K35/34 , C12N2501/105 , C12N2501/115 , C12N2501/15 , C12N2501/155 , C12N2501/16 , C12N2501/23 , C12N2501/734 , C12N2501/999 , C12N2506/1353 , C12Q1/6876 , C12Q1/6881 , C12Q2600/136 , C12Q2600/158 , G06F19/24
摘要： This document is related to a method for determining the cardio-generative potential of mammalian cells which comprises the assessment of a CARdiac generation Potential Index (CARPI) as a function of the quantification of the expression of genes of said cells. It also relates to a method for quantitatively assessing the modification of this cardio-generative potential and the cardiogenic potential of a treatment aiming at cellular differentiation.
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