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公开(公告)号：EP2895471A1
公开(公告)日：2015-07-22
申请号：EP13748452.3
申请日：2013-08-07
发明人： WANG, Tao , ZHANG, Zhongxing , KADOW, John F. , MEANWELL, Nicholas A. , RUEDIGER, Edward H. , JAMES, Clint A. , DEON, Daniel H. , CARINI, David J. , JOHNSON, Barry L.
IPC分类号： C07D401/06 , C07D471/04 , A61K31/454 , A61K31/437 , A61P31/18
CPC分类号： C07D471/04 , A61K31/454 , A61K31/4545 , A61K45/06 , C07D401/06
摘要： Compounds of Formula I, including pharmaceutically acceptable salts thereof: formule (I): wherein A is selected from the group consisting of:formule (II) and wherein Z is selected from the group consisting of: formule (III):,, and. are useful as HIV attachment inhibitors.
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公开(公告)号：EP1629000B1
公开(公告)日：2009-02-18
申请号：EP04759941.0
申请日：2004-04-16
发明人： MCPHEE, Fiona , CAMPBELL, Jeffrey Allen , LI, Wenying , D'ANDREA, Stanley , ZHENG, Zhizhen Barbara , GOOD, Andrew Charles , CARINI, David J. , JOHNSON, Barry L. , SCOLA, Paul Michael , BOY, Kenneth, M.
CPC分类号： C07K5/0804 , A61K38/00 , C12P7/62 , C12P13/04 , C12P41/005
摘要： Macrocyclic isoquinoline are disclosed having the general formula: A compound of formula 1: wherein R1 to R9, Q and W are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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3.发明公开MACROCYCLIC ISOQUINOLINE PEPTIDE INHIBITORS OF HEPATITIS C VIRUS 有权大环ISOCHINOLINPEPTIDINHIBITOREN丙型肝炎病毒的
公开(公告)号：EP1629000A2
公开(公告)日：2006-03-01
申请号：EP04759941.0
申请日：2004-04-16
发明人： MCPHEE, Fiona , CAMPBELL, Jeffrey Allen , LI, Wenying , D'ANDREA, Stanley , ZHENG, Zhizhen Barbara , GOOD, Andrew Charles , CARINI, David J. , JOHNSON, Barry L. , SCOLA, Paul Michael
CPC分类号： C07K5/0804 , A61K38/00 , C12P7/62 , C12P13/04 , C12P41/005
摘要： Macrocyclic isoquinoline are disclosed having the general formula: A compound of formula 1: wherein R1 to R9, Q and W are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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