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公开(公告)号:EP2183252A2
公开(公告)日:2010-05-12
申请号:EP08828571.3
申请日:2008-08-01
IPC分类号: C07D487/04 , A61K31/55 , A61P31/20
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:EP4081523A1
公开(公告)日:2022-11-02
申请号:EP20842859.9
申请日:2020-12-22
发明人: GENTLES, Robert G. , VELAPARTHI, Upender , DING, Min , OLSON, Richard E. , MARTIN, Scott W. , ROY, Saumya , JALAGAM, Prasada Rao , WARRIER, Jayakumar Sankara , CHUPAK, Louis , GRUNENFELDER, Denise
IPC分类号: C07D471/04 , C07D487/04 , A61K31/4375 , A61K31/519 , A61P35/00
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3.7H-INDOLO[2,1-A][2]BENZAZEPINE-10-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF HEPATITIS C 有权
标题翻译: 7H吲哚并[2,1-A] [2]苯并氮杂-10-羧酸衍生物用于治疗丙型肝炎的治疗公开(公告)号:EP2280975B1
公开(公告)日:2014-01-01
申请号:EP09743440.1
申请日:2009-05-05
IPC分类号: C07D487/04 , A61K31/55 , A61P31/14
CPC分类号: C07D487/04 , C07D471/08 , C07D487/08 , C07D498/08
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4.7H-INDOLOÝ2,1-A¨Ý2¨BENZAZEPINE-10-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF HEPATITIS C 有权
标题翻译: 7H吲哚并[2,1-A] [2]苯并氮杂-10-羧酸衍生物用于治疗丙型肝炎的治疗公开(公告)号:EP2280975A1
公开(公告)日:2011-02-09
申请号:EP09743440.1
申请日:2009-05-05
IPC分类号: C07D487/04 , A61K31/55 , A61P31/14
CPC分类号: C07D487/04 , C07D471/08 , C07D487/08 , C07D498/08
摘要: The invention encompasses compounds of formula (I) as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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5.
公开(公告)号:EP3131876A2
公开(公告)日:2017-02-22
申请号:EP15772037.6
申请日:2015-04-10
发明人: CHUPAK, Louis S. , DING, Min , MARTIN, Scott W. , ZHENG, Xiaofan , HEWAWASAM, Piyasena , CONNOLLY, Timothy P. , XU, Ningning , YEUNG, Kap-Sun , ZHU, Juliang , LANGLEY, David R. , TENNEY, Daniel J. , SCOLA, Paul Michael
IPC分类号: C07C255/54 , C07D215/14 , C07D215/18 , C07D231/56 , C07D405/04 , C07D239/26 , C07D261/08 , C07D271/06 , C07D207/26 , C07D207/335 , C07D213/30
CPC分类号: C07D319/18 , A61K31/165 , A61K31/277 , A61K31/357 , A61K31/40 , A61K31/4015 , A61K31/416 , A61K31/4178 , A61K31/4245 , A61K31/427 , A61K31/4433 , A61K31/453 , A61K31/4545 , A61K31/47 , A61K31/472 , A61K31/496 , A61K31/505 , A61K31/5377 , A61K31/541 , A61K45/06 , C07C233/36 , C07C235/42 , C07C255/13 , C07C255/54 , C07C271/28 , C07C317/22 , C07D207/26 , C07D207/335 , C07D213/30 , C07D215/14 , C07D215/18 , C07D217/16 , C07D231/56 , C07D239/26 , C07D261/08 , C07D271/06 , C07D405/04 , C07D405/12 , C07D405/14 , C07D413/12 , C07D417/12 , Y02A50/463 , A61K2300/00
摘要: The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.
摘要翻译: 本公开一般涉及可用作免疫调节剂的化合物。 本文提供化合物,包含这些化合物的组合物及其使用方法。 本公开进一步涉及包含至少一种根据本公开的化合物的药物组合物,其可用于治疗各种疾病,包括癌症和感染性疾病。
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公开(公告)号:EP3814348A1
公开(公告)日:2021-05-05
申请号:EP19744923.4
申请日:2019-06-26
发明人: VELAPARTHI, Upender , CHUPAK, Louis S. , DARNE, Chetan Padmakar , DING, Min , GENTLES, Robert G. , HUANG, Yazhong , KAMBLE, Manjunatha Narayana Rao , MARTIN, Scott W. , MANNOORI, Raju , MCDONALD, Ivar M. , OLSON, Richard E. , RAHAMAN, Hasibur , JALAGAM, Prasada Rao , ROY, Saumya , TONUKUNURU, Gopikishan , VELAIAH, Sivasudar , WARRIER, Jayakumar Sankara , ZHENG, Xiaofan , TOKARSKI, John S. , DASGUPTA, Bireshwar , REDDY, Kotha Rathnakar , RAJA, Thiruvenkadam
IPC分类号: C07D471/04 , A61P35/00 , A61K31/496
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公开(公告)号:EP3814347A1
公开(公告)日:2021-05-05
申请号:EP19740166.4
申请日:2019-06-26
发明人: CHUPAK, Louis S. , DING, Min , GENTLES, Robert G. , HUANG, Yazhong , MARTIN, Scott W. , MCDONALD, Ivar M. , MERCER, Stephen E. , OLSON, Richard E. , VELAPARTHI, Upender , WICHROSKI, Michael , ZHENG, Xiaofan
IPC分类号: C07D471/04 , A61P35/00 , A61K31/496
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公开(公告)号:EP2183252B1
公开(公告)日:2015-01-14
申请号:EP08828571.3
申请日:2008-08-01
IPC分类号: C07D487/04 , A61K31/55 , A61P31/20
CPC分类号: C07D487/04
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