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1.发明公开HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开HISTON DEACETYLASE HEMMER及其组合物和使用它们的方法
公开(公告)号：EP2968233A4
公开(公告)日：2016-08-03
申请号：EP14775793
申请日：2014-03-10
申请人： CHDI FOUNDATION INC
发明人： DOMINGUEZ CELIA , MUÑOZ-SAN JUAN IGNACIO , MAILLARD MICHEL , RAPHY GILLES , HAUGHAN ALAN F , LUCKHURST CHRISTOPHER A , JARVIS REBECCA E , BURLI ROLAND W , WISHART GRANT , HUGHES SAMANTHA J , ALLEN DANIEL R , PENROSE STEPHEN D , BRECCIA PERLA
IPC分类号： A61K31/16
CPC分类号： C07C233/60 , C07C259/08 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D209/46 , C07D213/54 , C07D213/56 , C07D213/58 , C07D215/06 , C07D215/14 , C07D231/12 , C07D231/56 , C07D235/06 , C07D235/08 , C07D239/26 , C07D263/56 , C07D263/57 , C07D265/30 , C07D265/36 , C07D277/64 , C07D277/66 , C07D295/073 , C07D307/79 , C07D307/81 , C07D311/96 , C07D333/54 , C07D401/12 , C07D413/06 , C07D471/04
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2.发明公开HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开组蛋白去乙酰化酶抑制剂和组合物以及申请流程。
公开(公告)号：EP2667709A4
公开(公告)日：2014-07-16
申请号：EP12738982
申请日：2012-01-23
申请人： CHDI FOUNDATION INC
发明人： LUCKHURST CHRISTOPHER A , HAUGHAN ALAN F , BRECCIA PERLA , STOTT ANDREW J , BURLI ROLAND W , HUGHES SAMANTHA J , MUNOZ-SANJUAN IGNACIO , DOMINGUEZ CELIA , MANGETTE JOHN E
IPC分类号： A01N37/08 , A61K31/19 , A61K31/357 , A61K31/403 , A61K31/415 , A61K31/421 , A61K31/4418 , A61K31/50 , A61K31/505 , A61K31/536
CPC分类号： C07D401/06 , C07C259/08 , C07C311/14 , C07C2601/02 , C07C2601/14 , C07D205/04 , C07D207/10 , C07D209/44 , C07D209/46 , C07D209/82 , C07D211/58 , C07D211/70 , C07D213/56 , C07D213/74 , C07D215/18 , C07D231/12 , C07D233/61 , C07D233/64 , C07D237/08 , C07D239/26 , C07D263/32 , C07D265/36 , C07D267/14 , C07D277/30 , C07D295/155 , C07D317/46 , C07D319/18 , C07D401/04 , C07D409/08 , C07D413/04 , C07D417/08 , C07D471/04 , C07D487/04 , C07D491/10
摘要： Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
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公开(公告)号：EP3148539A4
公开(公告)日：2018-01-03
申请号：EP15803976
申请日：2015-06-01
申请人： CHDI FOUNDATION INC
发明人： DOMINGUEZ CELIA , MUN OZ-SANJUAN IGNACIO , LUCKHURST CHRISTOPHER A , ALLEN DANIEL R , RAPHY GILLES , BÛRLI ROLAND W , BRECCIA PERLA , HAUGHAN ALAN F , WISHART GRANT , HUGHES SAMANTHA J , JARVIS REBECCA E , VATER HUW D , PENROSE STEPHEN D , WALL MICHAEL , STOTT ANDREW J , SAVILLE-STONES ELIZABETH
IPC分类号： C07D231/54 , A61K31/423 , A61K31/4245 , A61K31/4709 , A61P25/28 , C07D275/04 , C07D277/60 , C07D401/04 , C07D403/04 , C07D417/04
CPC分类号： C07D417/04 , C07C259/08 , C07D231/54 , C07D231/56 , C07D239/70 , C07D239/74 , C07D239/88 , C07D275/04 , C07D277/60 , C07D401/04 , C07D403/04
摘要： Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use. The condition or disorder mediated by HDAC comprises a neurodegenerative pathology. Accordingly, also provided is a method of treating a neurodegenerative pathology mediated by HDAC in a subject in need of such a treatment, comprising administering to the subject a therapeutically effective amount of at least one compound, or pharmaceutically acceptable salt thereof, described herein.
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公开(公告)号：EP2968207A4
公开(公告)日：2016-09-28
申请号：EP14775535
申请日：2014-03-10
申请人： CHDI FOUNDATION INC
发明人： DOMINGUEZ CELIA , MUÑOZ-SANJUAN IGNACIO , MAILLARD MICHEL , LUCKHURST CHRISTOPHER A , JARVIS REBECCA E , BÜRLI ROLAND W , ALLEN DANIEL R , HAUGHAN ALAN F , BRECCIA PERLA , VATER HUW D , STOTT ANDREW J , PENROSE STEPHEN D , WALL MICHAEL , SAVILLE-STONES ELIZABETH A , WISHART GRANT , HUGHES SAMANTHA J
IPC分类号： C07D231/12 , A61K31/015 , A61K31/02 , A61K31/166 , C07C259/08 , C07D213/56 , C07D213/61 , C07D213/64 , C07D231/56 , C07D239/26 , C07D241/12 , C07D241/42 , C07D261/20 , C07D275/04 , C07D277/62 , C07D277/64 , C07D333/60 , C07D471/04
CPC分类号： C07D471/04 , C07C259/08 , C07C2601/02 , C07C2601/10 , C07D213/56 , C07D213/61 , C07D213/64 , C07D231/12 , C07D231/56 , C07D239/26 , C07D241/12 , C07D241/42 , C07D261/20 , C07D275/04 , C07D277/62 , C07D277/64 , C07D333/60
摘要： Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
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公开(公告)号：EP2968232A4
公开(公告)日：2016-08-03
申请号：EP14773968
申请日：2014-03-10
申请人： CHDI FOUNDATION INC
发明人： DOMINGUEZ CELIA , MUÑOZ-SANJUAN IGNACIO , BEAUMONT VAHRI , BECONI MARIA , BÜRLI ROLAND W , HAUGHAN ALAN F , LUCKHURST CHRISTOPHER A , WALL MICHAEL , RAPHY GILLES , THOMAS BETH
IPC分类号： C07D239/26 , A61K31/505 , A61P25/00 , A61P35/00
CPC分类号： A61K31/505 , C07D239/26
摘要： Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
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