-
1.发明公开COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES 审中-公开VERBINDUNGEN MIT THROMBOPOIETINARTIGER WIRKUNG
公开(公告)号：EP1291341A4
公开(公告)日：2005-04-27
申请号：EP01934428
申请日：2001-05-30
IPC分类号： A61K38/00 , A61P7/04 , C07C237/22 , C07D209/18 , C07D213/78 , C07D333/24 , C07D333/34
CPC分类号： C07D213/78 , A61K38/00 , C07C237/22 , C07D209/18 , C07D333/24 , C07D333/34
摘要： Compounds of the general formula (1) or pharmacologically acceptable salts thereof, exhibiting thrombopoietin-like activities: wherein E is methylidyne or nitrilo; R1 is optionally substituted aryl or optionally substituted heteroaryl; R2 is hydrogen or alkyl; W1 is an amino acid residue; A is carbonyl or sulfonyl; X1 is optionally substituted alkylene or optionally substituted alkenylene; and p is 0 or 1.
摘要翻译： 具有血小板生成素样活性的通式（1）的化合物或其药理学上可接受的盐：其中E是次甲基或次氮基; R1是任选取代的芳基或任选取代的杂芳基; R2是氢或烷基; W1是氨基酸残基; A是羰基或磺酰基; X1是任选取代的亚烷基或任选取代的亚烯基; 并且p是0或1。
-
公开(公告)号：EP2930176A4
公开(公告)日：2016-06-01
申请号：EP13862318
申请日：2013-12-10
发明人： NISHIMURA YOSHIKAZU , ESAKI TORU , TAMURA TATSUYA
IPC分类号： C07D471/10 , A61K31/438 , A61P3/14 , A61P5/18 , A61P43/00 , C07D519/00
CPC分类号： C07D471/10 , C07D519/00
摘要： The present invention provides compounds represented by formula (1) below and pharmacologically acceptable salts thereof: wherein R 1 , R 2 , R 3 , and R 4 are as defined in the claims.
摘要翻译： 本发明提供由下式（1）表示的化合物及其药理学上可接受的盐：其中R 1，R 2，R 3和R 4如权利要求中所定义。
-
公开(公告)号：EP2433940A4
公开(公告)日：2012-10-10
申请号：EP10769728
申请日：2010-04-27
发明人： ESAKI TORU , NISHIMURA YOSHIKAZU , ISSHIKI YOSHIAKI , OKAMOTO NAOKI , FURUTA YOSHIYUKI , MIZUTANI AKEMI , OHTA MASATERU , LAI WAYNE WEN , KOTAKE TOMOYA
IPC分类号： C07D471/10 , A61K31/438 , A61K31/444 , A61K31/496 , A61K31/5355 , A61P5/20 , A61P7/08 , A61P19/02 , A61P19/08 , A61P43/00 , C07D487/10
CPC分类号： C07D471/10 , C07D471/20 , C07D491/107 , C07D513/20 , C07D513/22 , C07D515/20
-
公开(公告)号：EP1156037A4
公开(公告)日：2002-03-20
申请号：EP00901903
申请日：2000-01-26
发明人： KITAMURA HIDETOMO , KATO ATSUHIKO , ESAKI TORU
IPC分类号： A61K31/404 , A61K31/405 , A61K31/443 , A61K31/4433 , A61K31/4439 , A61P19/08 , C07D209/38 , C07D209/40 , C07D401/06 , C07D403/12 , C07D405/06 , C12N5/02 , A61K31/454 , C07D209/36 , C07D401/12
CPC分类号： C07D401/06 , A61K31/404 , A61K31/405 , A61K31/443 , A61K31/4433 , A61K31/4439 , C07D209/38 , C07D209/40 , C07D403/12 , C07D405/06
摘要： Chondrongenesis promotors characterized by containing as the active ingredient compounds represented by general formula (I) or salts thereof, wherein R1 is halogeno, lower alkyl, lower alkoxy, or the like; R2 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy, acyl, aryl, a heterocyclic group, or the like; R3 is lower alkyl, cycloalkyl, aryl, a heterocyclic group, or the like; R4 is hydrogen, lower alkyl, aryl, a heterocyclic group, or the like; X and Y are each -CH¿2?-, -NH-, or -O-; and n is an integer of 0 to 4.
-
-
-
搜索结果
4 条记录 (耗时 0.008 秒)
