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    MICROORGANISM PRODUCING LACTIC ACID AND METHOD FOR PRODUCING LACTIC ACID USING SAME
    1.
    发明公开
    MICROORGANISM PRODUCING LACTIC ACID AND METHOD FOR PRODUCING LACTIC ACID USING SAME 审中-公开
    微生物生产乳酸和用其生产乳酸的方法

    公开(公告)号：EP3309254A1

    公开(公告)日：2018-04-18

    申请号：EP16807847.5

    申请日：2016-06-10

    申请人： CJ Cheiljedang Corporation

    发明人： KIM, Seon Hye ,  LEE, Tae Hee ,  YANG, Young Lyeol ,  YANG, Eun Bin ,  NA, Kyungsu ,  HA, Cheol Woong

    IPC分类号： C12N15/81 ,  C12P7/56

    摘要： The present applicaiton relates to a microorganism of the genus Saccharomyces producing lactic acid and a method for preparing lactic acid using the same. More specifically, the present applicaiton relates to a microorganism of the genus Saccharomyces producing lactic acid, wherein the microorganism is modified to weaken or inactivate the activity of pyruvate decarboxylase (PDC) compared to its endogenous activity, to introduce the activity of ATP-citrate lyase (ACL), and to enhance pyruvate biosynthetic pathway compared to its endogenous biosynthetic pathway, and a method for producing lactic acid using the microorganism.

    摘要翻译： 本发明涉及产生乳酸的酵母属微生物和使用该微生物制备乳酸的方法。 更具体地说，本发明涉及产生乳酸酵母属的微生物，其中微生物经修饰以削弱或灭活丙酮酸脱羧酶（PDC）与其内源活性相比的活性，以引入ATP-柠檬酸裂合酶 （ACL），并且与其内源性生物合成途径相比增强丙酮酸生物合成途径，以及使用该微生物生产乳酸的方法。

    NOVEL STRAIN PRODUCING D-LACTIC ACID AND USE THEREOF
    3.
    发明公开
    NOVEL STRAIN PRODUCING D-LACTIC ACID AND USE THEREOF 审中-公开
    维也纳大魔王维多利亚时代

    公开(公告)号：EP2843039A1

    公开(公告)日：2015-03-04

    申请号：EP13780610.5

    申请日：2013-04-24

    申请人： Cj Cheiljedang Corporation

    发明人： YANG, Eun Bin ,  LEE, Tae Hee ,  KIM, Seon Hye ,  YANG, Young Lyeol ,  LI, Hong Xian

    IPC分类号： C12N1/21

    CPC分类号： C12P7/56 ,  C12N9/0006 ,  C12Y101/01027 ,  C12Y101/01028

    摘要： The present invention relates to a method for preparing a D-lactic acid-producing strain modified to inhibit L-lactate dehydrogenase (L-LDH) activity and to introduce D-lactate dehydrogenase (D-LDH) activity in an L-lactic acid-producing strain, a mutated D-lactic acid-producing strain prepared by the above method, and a method for producing D-lactic acid including the steps of culturing the strain and recovering D-lactic acid from the culture media.

    摘要翻译： 本发明涉及一种修饰成抑制L-乳酸脱氢酶（L-LDH）活性并在L-乳酸脱氢酶中引入D-乳酸脱氢酶（D-LDH）活性的D-乳酸生产菌株的制备方法， 生产菌株，通过上述方法制备的突变的D-乳酸生产菌株和D-乳酸的生产方法，包括培养菌株并从培养基中回收D-乳酸的步骤。