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1.发明公开MICROORGANISM HAVING IMPROVED PRODUCTION OF LACTIC ACID AND METHOD FOR PRODUCING LACTIC ACID BY USING SAME 审中-公开具有改进的乳酸生产的微生物及使用相同方法生产乳酸的方法
公开(公告)号：EP3309247A1
公开(公告)日：2018-04-18
申请号：EP15895034.5
申请日：2015-06-12
发明人： YANG, Eun Bin , LEE, Tae Hee , KIM, Seon Hye , SONG, Gyuhyeon , HA, Cheol Woong , NA, Kyungsu , YANG, Young Lyeol , KANG, Min Sun , LEE, Hyo Hyoung
CPC分类号： C12P7/56 , C12N1/18 , C12N9/0008 , C12N9/88 , C12N9/93 , C12Y102/01003 , C12Y401/01001 , C12Y602/01001
摘要： The present invention relates to Saccharomyces sp. capable of producing lactic acid with a decreased activity of pyruvate decarboxylase (PDC) and increased activities of aldehyde dehydrogenase (ALD) and acetyl-CoA synthetase (ACS), and a method of producing lactic acid from the culture medium obtained by culturing the microorganism.
摘要翻译： 本发明涉及酵母属（Saccharomyces sp。）。 其能够产生丙酮酸脱羧酶（PDC）活性降低并且醛脱氢酶（ALD）和乙酰-CoA合成酶（ACS）活性增加的乳酸，以及通过培养微生物获得的培养基生产乳酸的方法。
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公开(公告)号：EP4219697A1
公开(公告)日：2023-08-02
申请号：EP21915421.8
申请日：2021-09-08
发明人： KIM, Yeonsoo , HA, Cheol Woong , YANG, Eun Bin , IM, Yeong Eun
摘要： Provided are a novel glutamate-cysteine ligase variant and a method of producing glutathione using the same.
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3.发明公开
公开(公告)号：EP4353820A1
公开(公告)日：2024-04-17
申请号：EP22820531.6
申请日：2022-06-07
发明人： IM, Yeong Eun , HA, Cheol Woong , YANG, Eun Bin , KIM, Yeonsoo
CPC分类号： C12N9/0004 , C12P21/02 , C12N15/81
摘要： The present application relates to a superoxide dismutase 1 variant and a method for producing glutathione or derivatives thereof using the same.
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公开(公告)号：EP2960326B1
公开(公告)日：2019-04-03
申请号：EP15739495.8
申请日：2015-05-08
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5.发明公开MICROORGANISM PRODUCING LACTIC ACID AND METHOD FOR PRODUCING LACTIC ACID USING SAME 审中-公开微生物生产乳酸和用其生产乳酸的方法
公开(公告)号：EP3309254A1
公开(公告)日：2018-04-18
申请号：EP16807847.5
申请日：2016-06-10
发明人： KIM, Seon Hye , LEE, Tae Hee , YANG, Young Lyeol , YANG, Eun Bin , NA, Kyungsu , HA, Cheol Woong
摘要： The present applicaiton relates to a microorganism of the genus Saccharomyces producing lactic acid and a method for preparing lactic acid using the same. More specifically, the present applicaiton relates to a microorganism of the genus Saccharomyces producing lactic acid, wherein the microorganism is modified to weaken or inactivate the activity of pyruvate decarboxylase (PDC) compared to its endogenous activity, to introduce the activity of ATP-citrate lyase (ACL), and to enhance pyruvate biosynthetic pathway compared to its endogenous biosynthetic pathway, and a method for producing lactic acid using the microorganism.
摘要翻译： 本发明涉及产生乳酸的酵母属微生物和使用该微生物制备乳酸的方法。 更具体地说，本发明涉及产生乳酸酵母属的微生物，其中微生物经修饰以削弱或灭活丙酮酸脱羧酶（PDC）与其内源活性相比的活性，以引入ATP-柠檬酸裂合酶 （ACL），并且与其内源性生物合成途径相比增强丙酮酸生物合成途径，以及使用该微生物生产乳酸的方法。
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6.发明公开MICROORGANISM CAPABLE OF ENHANCING LACTIC ACID PRODUCTION AND METHOD FOR PRODUCING LACTIC ACID USING SAME 审中-公开微生物，这使正在加强牛奶酸生产及其制造方法乳酸及其用途下
公开(公告)号：EP2960326A1
公开(公告)日：2015-12-30
申请号：EP15739495.8
申请日：2015-05-08
发明人： YANG, Eun Bin , LEE, Tae Hee , KIM, Seon Hye , SONG, Gyu Hyeon , HA, Cheol Woong , NA, Kyung Su , YANG, Young Lyeol , KANG, Min Sun , LEE, Hyo Hyoung
CPC分类号： C12P7/56 , C12N9/0006 , C12N9/0008 , C12N9/88 , C12N9/93 , C12Y101/01027 , C12Y101/01028 , C12Y401/01001 , C12Y602/01001
摘要： The present invention relates to Saccharomyces sp. capable of producing lactic acid with a decreased activity of pyruvate decarboxylase (PDC) and increased activities of aldehyde dehydrogenase (ALD) and acetyl-CoA synthetase (ACS), and a method of producing lactic acid from the culture medium obtained by culturing the microorganism.
摘要翻译： 本发明涉及酵母属。 能够产生乳酸与丙酮酸脱羧酶（PDC）和醛脱氢酶（ALD）和乙酰-CoA合成酶（ACS），以及生产从通过培养微生物得到的培养培养基的乳酸的方法的增加的活动的降低的活性。
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公开(公告)号：EP2843039A1
公开(公告)日：2015-03-04
申请号：EP13780610.5
申请日：2013-04-24
发明人： YANG, Eun Bin , LEE, Tae Hee , KIM, Seon Hye , YANG, Young Lyeol , LI, Hong Xian
IPC分类号： C12N1/21
CPC分类号： C12P7/56 , C12N9/0006 , C12Y101/01027 , C12Y101/01028
摘要： The present invention relates to a method for preparing a D-lactic acid-producing strain modified to inhibit L-lactate dehydrogenase (L-LDH) activity and to introduce D-lactate dehydrogenase (D-LDH) activity in an L-lactic acid-producing strain, a mutated D-lactic acid-producing strain prepared by the above method, and a method for producing D-lactic acid including the steps of culturing the strain and recovering D-lactic acid from the culture media.
摘要翻译： 本发明涉及一种修饰成抑制L-乳酸脱氢酶（L-LDH）活性并在L-乳酸脱氢酶中引入D-乳酸脱氢酶（D-LDH）活性的D-乳酸生产菌株的制备方法， 生产菌株，通过上述方法制备的突变的D-乳酸生产菌株和D-乳酸的生产方法，包括培养菌株并从培养基中回收D-乳酸的步骤。
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公开(公告)号：EP4112725A1
公开(公告)日：2023-01-04
申请号：EP21774874.8
申请日：2021-03-24
发明人： YANG, Eun Bin , HA, Cheol Woong , KIM, Yeonsoo , IM, Yeong Eun
摘要： Provided are a novel glutamate-cysteine ligase variant and a method of producing glutathione using the same.
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公开(公告)号：EP4053276A1
公开(公告)日：2022-09-07
申请号：EP21781893.9
申请日：2021-04-02
发明人： HA, Cheol Woong , IM, Yeong Eun , YANG, Eun Bin , KIM, Yeonsoo , KIM, Hyung Joon
摘要： Provided are a novel promoter, a vector including the same, a microorganism including the same, and a method of producing glutathione using the same.
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公开(公告)号：EP4026895A1
公开(公告)日：2022-07-13
申请号：EP20882475.5
申请日：2020-09-18
发明人： HA, Cheol Woong , YANG, Eun Bin , KIM, Hyo Jin , KIM, Hyung Joon , IM, Yeong Eun
IPC分类号： C12N1/16 , C12P21/02 , A23K20/147 , A23L33/18 , A61K8/64 , A61K8/9728 , A61K36/064 , A61K38/06 , C12R1/865
摘要： Provided are a novel yeast strain producing glutathione and a method of producing glutathione using the same.
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