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8 条记录 (耗时 0.013 秒)

    COATED IMPLANTABLE MEDICAL DEVICE
    2.
    发明公开
    COATED IMPLANTABLE MEDICAL DEVICE 有权
    涂层纸，植入式医疗设备

    公开(公告)号：EP1330273A1

    公开(公告)日：2003-07-30

    申请号：EP01987197.9

    申请日：2001-10-31

    申请人： Cook Incorporated ,  MED INSTITUTE, INC.

    发明人： RAGHEB, Anthony, O. ,  BATES, Brian, L. ,  STEWART, Joseph, M., IV ,  BOURDEAU, William, J. ,  CHOULES, Brian, D. ,  PURDY, James, D. ,  FEARNOT, Neal, E.

    IPC分类号： A61L31/16 ,  A61L27/54

    CPC分类号： A61L27/54 ,  A61F2/86 ,  A61F2250/0067 ,  A61L31/16 ,  A61L2300/252 ,  A61L2300/414 ,  A61L2300/606

    摘要： A medical device (10) includes a structure (12) adapted for introduction into a patient, the structure (12) being formed of a preferably non-porous base material (14) having a roughened or textured surface (16). The structure (12) is conveniently configured as a vascular stent with a base material (14) of stainless steel, nitinol or another suitable material. The medical device (10) also includes a layer (18) of a bioactive material posited directly upon the roughened or textured surface (16) of the base material (14) of the structure (12). The surface (16) of the base material (14) is roughened or textured by etching or by abrasion with sodium bicarbonate or another suitable grit. A preferred roughened or textured surface (16) is thought to have a mean surface roughness of about 10 νin. (about 250 nm) and a surface roughness range between about 1/νin. and about 100 νin. (about 25 nm and about 2.5 νm). The particularly preferred use of sodium bicarbonate as the abrasive to provide roughness or texture to the surface (16) of the base material (14) of the structure (12) is additionally advantageous in the low toxicity of the sodium bicarbonate to production workers, the ease of product and waste cleanup, and the biocompatibility of any residual sodium bicarbonate.

    COATED IMPLANTABLE MEDICAL DEVICE
    3.
    发明授权
    COATED IMPLANTABLE MEDICAL DEVICE 有权
    涂层纸，植入式医疗设备

    公开(公告)号：EP1330273B1

    公开(公告)日：2007-07-25

    申请号：EP01987197.9

    申请日：2001-10-31

    申请人： Cook Incorporated ,  MED INSTITUTE, INC.

    发明人： RAGHEB, Anthony, O. ,  BATES, Brian, L. ,  STEWART, Joseph, M., IV ,  BOURDEAU, William, J. ,  CHOULES, Brian, D. ,  PURDY, James, D. ,  FEARNOT, Neal, E.

    IPC分类号： A61L31/16 ,  A61L27/54

    CPC分类号： A61L27/54 ,  A61F2/86 ,  A61F2250/0067 ,  A61L31/16 ,  A61L2300/252 ,  A61L2300/414 ,  A61L2300/606

    摘要： A medical device (10) includes a structure (12) adapted for introduction into a patient, the structure (12) being formed of a preferably non-porous base material (14) having a roughened or textured surface (16). The structure (12) is conveniently configured as a vascular stent with a base material (14) of stainless steel, nitinol or another suitable material. The medical device (10) also includes a layer (18) of a bioactive material posited directly upon the roughened or textured surface (16) of the base material (14) of the structure (12). The surface (16) of the base material (14) is roughened or textured by etching or by abrasion with sodium bicarbonate or another suitable grit. A preferred roughened or textured surface (16) is thought to have a mean surface roughness of about 10 νin. (about 250 nm) and a surface roughness range between about 1/νin. and about 100 νin. (about 25 nm and about 2.5 νm). The particularly preferred use of sodium bicarbonate as the abrasive to provide roughness or texture to the surface (16) of the base material (14) of the structure (12) is additionally advantageous in the low toxicity of the sodium bicarbonate to production workers, the ease of product and waste cleanup, and the biocompatibility of any residual sodium bicarbonate.

    ENDOVASCULAR FILTER
    6.
    发明公开
    ENDOVASCULAR FILTER 审中-公开
    ENDOVASKULÄRER过滤器

    公开(公告)号：EP1412014A2

    公开(公告)日：2004-04-28

    申请号：EP02744350.6

    申请日：2002-06-14

    申请人： Cook Incorporated

    发明人： GRIFFIN, Dennis ,  MOLGAARD-NIELSEN, Arne ,  RAGHEB, Anthony, O. ,  LEONARD II, Raymond, B.

    IPC分类号： A61M29/00

    CPC分类号： A61F2/01 ,  A61F2002/016 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0086

    摘要： Endovascular filter (10) including a plurality of struts (14) with distal ends (18) adapted to anchor the filter to the vessel wall after deployment, such as by having barbs (20), the filter being adapted to be retrieved if 5 desired. Strut distal ends (18) are coated with an antiproliferative agent (40) that inhibits the ingrowth of tissue around the filter, thereby permitting the filter to be retrieved and removed atraumatically after a prolonged period of time, thus extending the useful life of the retrievable filter. Optionally, the proximal end (22) of the filter may also be so coated, or the entire filter.