-
1.发明公开PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS 有权VERFAHREN ZUR HERSTELLUNG VON OPTISCH AKTIVEN BETA-AMINO ALKOHOLEN
公开(公告)号：EP1273665A1
公开(公告)日：2003-01-08
申请号：EP01908255.1
申请日：2001-03-02
发明人： SAKAMOTO, Keiji , KITA, Shinji , TSUZAKI, Kazuya , MORIKAWA, Tadanori , SHIMIZU, Sakayu , KATAOKA, Michihiko
IPC分类号： C12P13/00
CPC分类号： C12P13/001 , C12P13/008 , C12P41/002 , Y10S435/822 , Y10S435/865 , Y10S435/877 , Y10S435/911 , Y10S435/914 , Y10S435/917 , Y10S435/918
摘要： A process for producing an optical active β-amino alcohol, the method comprising the step of allowing at least one microorganism selected from the group consisting of microorganisms belonging to the genus Morganella and others, to act on an enantiomeric mixture of an α-aminoketone or a salt thereof having the general formula (I):
to produce an optical active β-amino alcohol with the desired optical activity having the general formula (II) described below in a high yield as well as in a highly selective manner:摘要翻译： 一种制备光学活性β-氨基醇的方法，所述方法包括允许至少一种选自属于摩根氏菌属的微生物的微生物和其它微生物作用于α-氨基酮或其对映异构体混合物 其具有通式（I）的盐：
以高产率和高度选择性的方式制备具有下述通式（II）的所需光学活性的光学活性β-氨基醇： -
公开(公告)号：EP1371731B1
公开(公告)日：2010-09-08
申请号：EP02701683.1
申请日：2002-03-01
发明人： SAKAMOTO, Keiji , KITA, Shinji , TSUZAKI, Kazuya , MORIKAWA, Tadanori , SHIMIZU, Sakayu , KATAOKA, Michihiko
CPC分类号： C12N9/0006 , C12P13/001 , C12P13/008
摘要： A protein which is an aminoketone asymmetric reductase acting on 1-2-methylaminopropiophenone to form d-pseudoephedrine and having the following physicochemical properties; and a nucleic acid encoding this protein: substrate: 1-2-methylaminopropiophenone; optimum pH value: 8.1; optimum temperature: 55 °C; coenzyme: NADP; and molecular weight: homotetramer of about 28500 Da.
-
公开(公告)号：EP1273665B1
公开(公告)日：2007-05-16
申请号：EP01908255.1
申请日：2001-03-02
发明人： SAKAMOTO, Keiji , KITA, Shinji , TSUZAKI, Kazuya , MORIKAWA, Tadanori , SHIMIZU, Sakayu , KATAOKA, Michihiko
CPC分类号： C12P13/001 , C12P13/008 , C12P41/002 , Y10S435/822 , Y10S435/865 , Y10S435/877 , Y10S435/911 , Y10S435/914 , Y10S435/917 , Y10S435/918
摘要： A process for producing an optical active beta -amino alcohol, the method comprising the step of allowing at least one microorganism selected from the group consisting of microorganisms belonging to the genus Morganella and others, to act on an enantiomeric mixture of an alpha -aminoketone or a salt thereof having the general formula (I): to produce an optical active beta -amino alcohol with the desired optical activity having the general formula (II) described below in a high yield as well as in a highly selective manner:
-
-
搜索结果
3 条记录 (耗时 0.012 秒)
