-
公开(公告)号：EP2655427A1
公开(公告)日：2013-10-30
申请号：EP11804499.9
申请日：2011-12-20
申请人： Dentsply DeTrey GmbH
发明人： KLEE, Joachim, E. , RITTER, Helmut , MAIER, Maximilian , GANSEL, Julia , FACHER, Andreas , ELSNER, Oliver , POHLE, Sven
CPC分类号： A61K6/0835 , C08F8/00 , C08F8/12 , C08F8/46 , C08F220/06 , C08F220/18 , C08F220/12 , C08L33/08 , C08L33/10 , C08L33/26
摘要： A process for producing a water-soluble, hydrolysis-stable, polymerizable polymer, comprising a) a step of copolymerizing a mixture comprising (i) a first copolymerizable monomer comprising at least one optionally protected carboxylic acid group and a first polymerizable organic moiety, and (ii) a second copolymerizable monomer comprising one or more optionally protected primary and/or secondary amino groups and a second polymerizable organic moiety, for obtaining an amino group containing copolymer; b) a step of coupling to the amino group containing copolymer a compound having a polymerizable moiety and a functional group reactive with an amino group of repeating units derived from the second copolymerizable monomer in the amino group containing copolymer obtained in the first step wherein the optionally protected amino group is deprotected, so that polymerizable pendant groups are linked to the backbone by hydrolysis-stable linking groups, and, optionally, a step of deprotecting the protected carboxylic acid group after step (a) or step (b), for obtaining a polymerizable polymer.
-
公开(公告)号：EP3984516A1
公开(公告)日：2022-04-20
申请号：EP21212142.0
申请日：2012-12-17
申请人： Dentsply DeTrey GmbH
发明人： STELZIG, Simon , KEMPTER, Jörg , NOERPEL, Stephanie , KLEE, Joachim E. , FACHER, Andreas , WALZ, Uwe , WEBER, Christoph
IPC分类号： A61K6/887 , A61K6/17 , A61K6/72 , A61K6/75 , A61K6/77 , A61K6/807 , A61K6/818 , A61K6/822 , C03C14/00 , C03C17/30 , C08K5/5419 , C09C1/40 , C09C3/00 , C09C3/04 , C09C3/08 , C09C3/12
摘要： A process for the preparation of composite filler particles having a degree of polymerization of the monomers of at least 50 % and less than 100 % as determined by any of the method disclosed in the description, comprising:
(a) coating a particulate glass filler having a median particle size (D50) of from 1 to 1200 nm with a coating composition containing a film-forming agent forming a coating layer on the surface of the particulate filler, said coating layer displaying reactive groups on the surface of the coating layer, said reactive groups being selected from addition polymerizable groups and step-growth polymerizable groups, thereby forming a coated particulate filler; subsequently or concurrently
(b) agglomerating the coated particulate filler for providing a granulation of the coated particulate filler wherein the granulation contains the coated particulate filler particles separated from and connected to each other by at least one coating layer, whereby the at least one coating layer may be crosslinked by crosslinking groups obtained by reacting the reactive groups, whereby the agglomeration is carried out by spray agglomeration or growth agglomeration;
for providing composite filler particles having a median particle size (D50) of from 1 to 70 µm, wherein reactive groups are transformed into crosslinking groups obtained by reacting reactive groups and optionally a further crosslinking agent, and wherein the particulate filler is the main component by volume of the composite filler particles.-
公开(公告)号：EP1771142A1
公开(公告)日：2007-04-11
申请号：EP05778581.8
申请日：2005-07-29
申请人： DENTSPLY DETREY GmbH
CPC分类号： A61K6/0017 , C08L33/00 , C08L63/00
摘要： One-component heat-curate sealant composition for the protection of exposed dental surfaces, comprising (a) a polymerisable monomer and/or oligomer which has at least two polymerizable douse bonds per molecule, and (b) an initiator system comprising benzoylperoxide in an amount of at least 2 wt.-% based on the total composition.
-
公开(公告)号：EP2655427B1
公开(公告)日：2019-03-27
申请号：EP11804499.9
申请日：2011-12-20
申请人： Dentsply DeTrey GmbH
-
公开(公告)号：EP2629740A1
公开(公告)日：2013-08-28
申请号：EP11771039.2
申请日：2011-10-18
申请人： Dentsply DeTrey GmbH
IPC分类号： A61K6/02 , A61K6/083 , C07C233/31
CPC分类号： A61K6/083 , A61K6/0023 , A61K6/0835 , C07C233/20 , C08L33/00
摘要： Dental composition comprising a water-soluble polymerizable compound of the following formula (1): €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ AX n €ƒ€ƒ€ƒ€ƒ€ƒ(1) wherein A is a straight chain or branched linker group containing least n nitrogen atoms, whereby the linker group has polyoxyalkylene and/or polyalkylene imine repeating units and optionally one or more acidic groups, X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, wherein each X may be the same or different and are represented by the following formula (2): wherein R 1 and R 2 are independent from each other and represent a hydrogen atom, a C 1-6 alkyl group or a group -(CH 2 ) m -COOM, wherein M represents a hydrogen atom or a metal atom, m is an integer of from 0 to 6, L is a bond or a C 1-6 alkylene group; and n is an integer of at least 1; (ii) an initiator system; optionally a polyacidic polymer; optionally water and/or a water soluble solvent; and optionally a particulate filler.
摘要翻译： 包含下式（1）的水溶性可聚合化合物的牙科组合物：（1）其中A 是含有至少n个氮原子的直链或支链连接基团，其中连接基团具有聚氧化烯和/或聚亚烷基亚胺重复单元和任选的一个或多个酸性基团，X是含有可聚合双键并与 A的氮原子，其中每个X可以相同或不同并且由下式（2）表示：其中R 1和R 2彼此独立并且表示氢原子，C 1-6烷基或 基团 - （CH 2）m -COOM，其中M表示氢原子或金属原子，m为0至6的整数，L为键或C 1-6亚烷基; 并且n是至少为1的整数; （ii）引发剂体系; 任选的多酸聚合物; 任选地水和/或水溶性溶剂; 和任选的颗粒填料。
-
公开(公告)号：EP2790639A1
公开(公告)日：2014-10-22
申请号：EP12813274.3
申请日：2012-12-17
申请人： Dentsply DeTrey GmbH
发明人： STELZIG, Simon , KEMPTER, Jörg , NOERPEL, Stephanie , KLEE, Joachim, E. , FACHER, Andreas , WALZ, Uwe , WEBER, Christoph
CPC分类号： C09D143/04 , A61K6/0008 , A61K6/0076 , A61K6/0085 , A61K6/0091 , A61K6/0215 , A61K6/024 , A61K6/025 , A61K6/083 , B01J2/16 , B05D7/24 , C01P2004/61 , C03C14/008 , C03C17/00 , C03C17/30 , C03C2214/12 , C08K3/40 , C08K5/5419 , C09C1/40 , C09C3/00 , C09C3/006 , C09C3/045 , C09C3/08 , C09C3/12 , C08L33/00
摘要： A process for the preparation of composite filler particles, comprising: (a) coating a particulate filler having a median particle size (D50) of from 1 to 1200 nm with a coating composition containing a film-forming agent forming a coating layer on the surface of the particulate filler, said coating layer displaying reactive groups on the surface of the coating layer, said reactive groups being selected from addition polymerizable groups and step-growth polymerizable groups, thereby forming a coated particulate filler; subsequently or concurrently (b) agglomerating the coated particulate filler, optionally in the presence of a further crosslinking agent and optionally in the presence of a further particulate filler not displaying reactive groups, for providing a granulation of the coated particulate filler wherein the granulation contains the coated particulate filler particles and the optional further particulate filler particles separated from and connected to each other by at least one coating layer, whereby the at least one coating layer may be crosslinked by crosslinking groups obtained by reacting the reactive groups and optionally a further crosslinking agent; (c) optionally milling, classifying and/or sieving the granulation of the coated particulate filler; and (d) optionally further crosslinking the granulation of the coated particulate filler; for providing composite filler particles having a median particle size (D50) of from 1 to 70 µm, wherein reactive groups are transformed into crosslinking groups obtained by reacting reactive groups and optionally a further crosslinking agent, and wherein the particulate filler is the main component by volume of the composite filler particles.
摘要翻译： 一种用于制备复合填料颗粒的方法，包括：（a）用含有在表面上形成涂层的成膜剂的涂料组合物涂布中值粒径（D50）为1-1200nm的颗粒填料 所述涂层在所述涂层表面上显示反应性基团，所述反应性基团选自可加聚的基团和可逐步生长的可聚合基团，从而形成涂覆的颗粒状填料; 随后或同时（b）任选地在另外的交联剂存在下和任选地在另外的没有显示反应性基团的颗粒状填料的存在下附聚涂覆的颗粒状填料，以提供涂覆的颗粒状填料的造粒，其中造粒剂含有 涂覆的颗粒状填料颗粒和任选的另外的颗粒状填料颗粒通过至少一个涂层彼此分离并且彼此连接，由此所述至少一个涂层可以通过交联基团交联，所述交联基团通过反应性基团和任选的另外的交联剂 ; （c）任选研磨，分级和/或筛分涂覆的颗粒状填料的颗粒; 和（d）任选地进一步交联涂布的颗粒状填料的颗粒; 用于提供具有1至70μm的中值粒度（D50）的复合填料颗粒，其中反应性基团被转化为通过反应性基团和任选的另外的交联剂反应获得的交联基团，并且其中所述颗粒填料是 复合填料颗粒的体积。
-
公开(公告)号：EP2629741A1
公开(公告)日：2013-08-28
申请号：EP11773194.3
申请日：2011-10-18
申请人： Dentsply DeTrey GmbH
IPC分类号： A61K6/02 , A61K6/083 , C07C233/31 , C07C233/09
CPC分类号： A61K6/0091 , A61K6/0023 , A61K6/08 , A61K6/083 , A61K6/0835 , A61K6/087 , A61K6/09 , C07C231/02 , C08L33/00 , C08L75/16 , C08L33/10 , C07C233/38
摘要： Dental composition comprising (i) a particulate filler; (ii) a polymerizable compound of the following formula (1), €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ AX n €ƒ€ƒ€ƒ€ƒ€ƒ(1) wherein A is a linker group containing at least n nitrogen atoms and optionally one or more acidic groups, X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, which X may be the same or different and are represented by the following formula (2) wherein R 1 and R 2 are independent from each other and represent a hydrogen atom, a C 1-6 alkyl group or a group -(CH 2 ) m -COOM, wherein M is hydrogen atom or a metal atom, and m is an integer of from 0 to 6, L is a bond, a C 1-6 alkylene group; and n is an integer of at least 1; provided that at least one X cannot be a (meth)acryl group; and (iii) an initiator system.
摘要翻译： 牙科组合物，其包含（i）颗粒状填充剂; （ii）下式（1）的可聚合化合物，其中A是连接基团（A），其中A是连接基团 基团，其含有至少n个氮原子和任选的一个或多个酸性基团，X是含有可聚合双键并与A的氮原子形成酰胺键的部分，X可以相同或不同并且由下式 （2）其中R 1和R 2彼此独立并且表示氢原子，C 1-6烷基或基团 - （CH 2）m -COOM，其中M是氢原子或金属原子，和 m是0至6的整数，L是键，C 1-6亚烷基; 并且n是至少为1的整数; 条件是至少一个X不能是（甲基）丙烯酰基; 和（iii）引发剂体系。
-
公开(公告)号：EP1771142B1
公开(公告)日：2011-09-07
申请号：EP05778581.8
申请日：2005-07-29
申请人： DENTSPLY DETREY GmbH
CPC分类号： A61K6/0017 , C08L33/00 , C08L63/00
摘要： One-component heat-curate sealant composition for the protection of exposed dental surfaces, comprising (a) a polymerisable monomer and/or oligomer which has at least two polymerizable douse bonds per molecule, and (b) an initiator system comprising benzoylperoxide in an amount of at least 2 wt.-% based on the total composition.
-
公开(公告)号：EP1848396A1
公开(公告)日：2007-10-31
申请号：EP06706947.6
申请日：2006-02-14
申请人： Dentsply DeTrey GmbH
发明人： BLACKWELL, Gordon , FACHER, Andreas
摘要： Polymerizable dental composite comprising a solid filler and an organic polymerizable matrix, said polymerizable matrix comprising: i) a polymerizable (meth)acrylic monomer having at least two polymerizable groups and ii) from 1.0 to 15 weight-% of a polymerizable monomer having a carboxylic acid group based on the total weight of said polymerizable matrix.
-
公开(公告)号：EP1351650A1
公开(公告)日：2003-10-15
申请号：EP02719692.2
申请日：2002-01-15
申请人： DENTSPLY DETREY GmbH
发明人： KLEE, Joachim, E. , WALZ, Uwe , FACHER, Andreas , WEBER, Christoph , MÜLHAUPT, Rolf , FREY, Holger , MÜH, Ekkehard
IPC分类号： A61K6/093
CPC分类号： A61K6/0008 , A61K6/083 , C08L51/085
摘要： A process for the preparation of a polymerisable dental composition comprising the steps of (a) preparing a liquid mixture comprising (i) 1 to 99% w/w of a hybrid monomer component containing at least one hybrid monomer compound having one hydrolysable siloxane group and at least one polymerisable organic moiety, and (ii) 99 to 1% w/w of a monomer component polymerisable with the polymerisable organic moiety of the hybrid monomer compounds; and (b) adding at least a stoichiometrically sufficient amount of water to the mixture to hydrolyse the hydrolysable siloxane group of the hybrid monomer compound and to form spherical polymerisable nanoparticles having an average particle size of from 1 to 100 nm dispersed in the monomer component, whereby the nanoparticles have a structure with Si-O-Si bonds and peripherally exposed polymerisable organic moieties.
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.019 秒)
