公开(公告)号：EP1140903B1

公开(公告)日：2004-08-04

申请号：EP99964279.6

申请日：1999-12-15

申请人： ELI LILLY AND COMPANY

发明人： BEIGHT, Douglas, Wade ,  CRAFT, Trelia, Joyce ,  DENNY, Carl, Penman ,  FRANCISKOVICH, Jeffry, Bernard ,  GOODSON, Theodore, Junior ,  HALL, Steven, Edward ,  HERRON, David, Kent ,  JOSEPH, Sajan Pariyadan ,  KLIMKOWSKI, Valentine, Joseph ,  MASTERS, John, Joseph ,  MENDEL, David ,  MILOT, Guy ,  PINEIRO-NUNEZ, Marta, Maria ,  SAWYER, Jason, Scott ,  SHUMAN, Robert, Theodore ,  SMITH, Gerald, Floyd ,  TEBBE, Anne, Louise ,  TINSLEY, Jennifer, Marie ,  WEIR, Leonard, Crayton ,  WILEY, Michael, Robert ,  YEE, Ying, Kwong

IPC分类号： C07D401/14 ,  C07D401/12 ,  C07D417/14 ,  C07D409/14 ,  C07D405/14 ,  C07D213/74 ,  A61K31/395 ,  A61K31/435 ,  A61K31/495 ,  A61P7/02

CPC分类号： C07D213/75 ,  C07D401/12 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D417/14

公开(公告)号：EP1140903A1

公开(公告)日：2001-10-10

申请号：EP99964279.6

申请日：1999-12-15

申请人： ELI LILLY AND COMPANY ,  Kyle, Jeffrey Alan

发明人： BEIGHT, Douglas, Wade ,  CRAFT, Trelia, Joyce ,  DENNY, Carl, Penman ,  FRANCISKOVICH, Jeffry, Bernard ,  GOODSON, Theodore, Junior ,  HALL, Steven, Edward ,  HERRON, David, Kent ,  JOSEPH, Sajan Pariyadan ,  KLIMKOWSKI, Valentine, Joseph ,  MASTERS, John, Joseph ,  MENDEL, David ,  MILOT, Guy ,  PINEIRO-NUNEZ, Marta, Maria ,  SAWYER, Jason, Scott ,  SHUMAN, Robert, Theodore ,  SMITH, Gerald, Floyd ,  TEBBE, Anne, Louise ,  TINSLEY, Jennifer, Marie ,  WEIR, Leonard, Crayton ,  WILEY, Michael, Robert ,  YEE, Ying, Kwong

IPC分类号： C07D401/14 ,  C07D401/12 ,  C07D417/14 ,  C07D409/14 ,  C07D405/14 ,  C07D213/74 ,  A61K31/395 ,  A61K31/435 ,  A61K31/495 ,  A61P7/02

CPC分类号： C07D213/75 ,  C07D401/12 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D417/14

摘要： This application relates to a compound of formula I (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.