专利检索 ap:("EMISPHERE TECH INC") AND inv:"O'TOOLE DORIS C" 第 1 页

1.

发明公开
COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS 有权
标题翻译：连接和组合物技术输送剂

公开(公告)号：EP1246792A4

公开(公告)日：2005-02-16

申请号：EP01908609

申请日：2001-01-12

申请人： EMISPHERE TECH INC

发明人： BOYD MARIA AURORA P , LEONE-BAY ANDREA , O'TOOLE DORIS C

IPC分类号： A61K9/08 , A61K9/00 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/727 , A61K38/00 , A61K38/21 , A61K38/22 , A61K38/23 , A61K38/27 , A61K38/28 , A61K38/29 , A61K47/02 , A61K47/10 , A61K47/16 , A61K47/18 , A61K47/48 , A61P3/10 , A61P5/10 , A61P5/14 , A61P5/18 , A61P7/02 , A61P43/00 , C07C235/48 , C07C235/64 , C07C229/00 , A61K51/00

CPC分类号： A61K31/195 , A61K9/0053 , A61K9/0073 , A61K31/557 , A61K31/727 , A61K38/21 , A61K38/23 , A61K38/27 , A61K38/28 , A61K38/29 , A61K47/183 , A61K47/541 , C07C235/64 , A61K2300/00

摘要： Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.

2.

发明公开
CRYSTALLINE FORMS OF THE DI-SODIUM SALT OF N-(5-CHLOROSALICYLOYL)-8-AMINOCAPRYLIC ACID 审中-公开
标题翻译：蓖麻仁DES DES ON ON ON ON ON ON V URE URE URE URE URE URE URE URE URE URE URE URE URE URE URE URE URE

公开(公告)号：EP1937627A4

公开(公告)日：2010-09-01

申请号：EP06814934

申请日：2006-09-18

申请人： EMISPHERE TECH INC

发明人： DHOOT NIKHIL , BAY WILLIAM ELLIOT , DINH STEVEN , MAJURU SHINGAI , CORVINO JOANNE P , O'TOOLE DORIS C

IPC分类号： C07C235/60

CPC分类号： A61K47/18 , C07B2200/13 , C07C231/24 , C07C235/52 , C07C235/60

摘要： The present invention relates to crystalline polymorphic forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid, pharmaceutical compositions containing the same, methods of preparing the same, and methods for facilitating the delivery of active agents with the same.

摘要翻译： 本发明涉及N-（5-氯水杨酰基）-8-氨基辛酸的二钠盐的结晶多晶型物，含有它们的药物组合物，其制备方法，以及促进活性剂递送方法一样。

3.

发明公开
METHOD OF PREPARING ALKYLATED SALICYLAMIDES VIA A DICARBOXYLATE INTERMEDIATE 有权
标题翻译：用于生产烷基化的水杨由二羧酸酯中间体

公开(公告)号：EP1284724A4

公开(公告)日：2007-10-17

申请号：EP01959913

申请日：2001-03-21

申请人： EMISPHERE TECH INC

发明人： BERNADINO JOSEPH N , O'TOOLE DORIS C , BAY WILLIAM E

IPC分类号： C07C231/12 , C07D265/36 , A61K45/00 , A61K47/16 , A61P1/04 , A61P3/00 , A61P3/02 , A61P5/06 , A61P7/00 , A61P7/02 , A61P9/00 , A61P9/08 , A61P9/12 , A61P11/06 , A61P13/00 , A61P15/00 , A61P19/08 , A61P19/10 , A61P31/00 , A61P35/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07C235/60 , C07C269/00 , C07C271/64 , C07D265/22 , C07D265/26

CPC分类号： C07D265/22 , C07C231/12 , C07C235/60 , C07D265/26 , Y02P20/55

摘要： The present invention relates to a method of preparing an alkylated salicylamide from a protected and activated salicylamide via a dicarboxylated salicylamide intermediate. The present invention also relates to dicarboxylic salicylamide delivery agent compounds for the delivery of active agents. Methods of administration are provided as well.