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公开(公告)号:EP3504319A1
公开(公告)日:2019-07-03
申请号:EP17847365.8
申请日:2017-08-29
发明人: KERNS, S., Jordan , WEN, Norman , LUCCHESI, Carol , HINOJOSA, Christopher , FRASER, Jacob , HAMILTON, Geraldine , VATINE, Gad , SANCES, Samuel , SVENDSEN, Clive , LEVNER, Daniel , SAREEN, Dhruv
IPC分类号: C12N5/071 , C12N5/079 , C12N5/0793 , C12N5/0797 , C12N15/85
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公开(公告)号:EP3365424A1
公开(公告)日:2018-08-29
申请号:EP16858141.1
申请日:2016-10-19
发明人: KERNS, S., Jordan , WEN, Norman , LUCCHESI, Carol , HINOJOSA, Chris , FRASER, Jacob , HAMILTON, Geraldine , VATINE, Gad , SANCES, Samuel , SVENDSEN, Clive , LEVNER, Daniel , SAREEN, Dhruv
IPC分类号: C12M1/34 , C12M3/00 , C12N5/0793 , C12N5/0797
CPC分类号: C12M23/16 , B01L3/5027 , B01L2200/0647 , B01L2300/0861 , C12M25/02 , C12M35/08 , C12N5/0618 , C12N5/0619 , C12N5/0622 , C12N5/069 , C12N5/0692 , C12N2502/081 , C12N2502/086 , C12N2502/28 , C12N2506/45 , C12N2531/00 , C12N2533/52 , C12N2533/54 , C12N2533/56 , C12N2535/10 , C12N2539/00 , C12Q1/02
摘要: The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.
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3.
公开(公告)号:EP3775161A1
公开(公告)日:2021-02-17
申请号:EP19782199.4
申请日:2019-04-05
IPC分类号: C12N5/07 , G01N27/40 , G01N27/403
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4.
公开(公告)号:EP3787649A1
公开(公告)日:2021-03-10
申请号:EP19796911.6
申请日:2019-04-05
IPC分类号: A61K35/30 , C12N5/074 , C12N5/0789 , C12N5/10
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公开(公告)号:EP3787613A1
公开(公告)日:2021-03-10
申请号:EP19796470.3
申请日:2019-04-05
IPC分类号: A61K31/215 , A61K31/22 , A61K36/47 , A61P25/16
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6.
公开(公告)号:EP4217114A1
公开(公告)日:2023-08-02
申请号:EP21873328.5
申请日:2021-09-22
发明人: SANCES, Samuel , SVENDSEN, Clive
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