公开(公告)号：EP0774462A4

公开(公告)日：1997-10-29

申请号：EP95926025

申请日：1995-07-25

申请人： FUJISAWA PHARMACEUTICAL CO

发明人： OKU TERUO ,  KAYAKIRI HIROSHI ,  SATOH SHIGEKI ,  ABE YOSHITO ,  SAWADA YUKI ,  INOUE TAKAYUKI ,  TANAKA HIROKAZU

IPC分类号： C07D209/48 ,  C07D235/06 ,  C07D235/08 ,  C07D235/12 ,  C07D235/16 ,  C07D235/26 ,  C07D235/28 ,  C07D235/30 ,  C07D263/56 ,  C07D277/64 ,  C07D307/79 ,  C07D307/80 ,  C07D307/84 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D413/12 ,  C07D498/04 ,  C07F7/18 ,  C07D263/58 ,  C07D277/66 ,  C07D277/68 ,  C07D277/70

CPC分类号： C07D209/48 ,  C07D235/06 ,  C07D235/08 ,  C07D235/12 ,  C07D235/16 ,  C07D235/26 ,  C07D235/28 ,  C07D235/30 ,  C07D263/56 ,  C07D277/64 ,  C07D307/79 ,  C07D307/80 ,  C07D307/84 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D413/12 ,  C07F7/1856

摘要： A heterocyclic compound represented by general formula (I) and a salt thereof; a process for producing the same; and a medicinal composition containing the same and useful for preventing and/or treating diseases of man or animal induced by bradykinin or an analog thereof. In said formula, a group represented by (a) is a group represented by (b), etc.; X represents O, S, or N-R5; R1 represents lower alkyl, etc.; R5 represents hydrogen, lower alkyl, etc.; R2 represents hydrogen, halogen, lower alkyl, etc.; R3 represents halogen, lower alkyl, etc.; R4 represents amino which may appropriately be substituted; and A represents lower alkylene.