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1.发明公开IMMUNOMODULATORY HUMAN MHC CLASS II ANTIGEN-BINDING POLYPEPTIDES 审中-公开抗原结合多肽用于免疫调节人类MHC类IIKOMPLEXES的
公开(公告)号：EP1303303A4
公开(公告)日：2009-06-10
申请号：EP01937390
申请日：2001-05-14
申请人： GPC BIOTECH AG , MORPHOSYS AG
IPC分类号： G01N33/50 , A61K38/00 , A61K39/00 , A61K39/395 , A61K48/00 , A61P1/00 , A61P1/16 , A61P1/18 , A61P3/10 , A61P13/12 , A61P17/06 , A61P19/02 , A61P21/04 , A61P25/02 , A61P29/00 , A61P37/02 , A61P37/06 , A61P43/00 , C07K16/28 , C12N1/15 , C12N1/19 , C12N5/06 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/02 , G01N33/53 , A61P37/00
CPC分类号： C07K16/2833 , A61K2039/505 , C07K16/28 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76
摘要： The present invention relates to human peptides/proteins comprising at least one antibody-based antigen-binding domain of human composition with a binding specificity for a human MHC class II antigen, wherein binding of said peptide/protein to said antigen expressed on the surface of a cell causes or leads to modulation of the immune system. The invention further relates to nucleic acids encoding said peptides/proteins, methods for production, immunosuppression, pharmaceutical and diagnostic compositions or kits comprising the peptides/proteins and uses of the peptides/proteins.
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2.发明公开HUMAN POLYPEPTIDES CAUSING OR LEADING TO THE KILLING OF CELLS INCLUDING LYMPHOID TUMOR CELLS 审中-公开人多肽WHAT细胞死亡，尤其是淋巴肿瘤细胞导致
公开(公告)号：EP1289551A4
公开(公告)日：2009-06-10
申请号：EP01935513
申请日：2001-05-14
申请人： GPC BIOTECH AG , MORPHOSYS AG
IPC分类号： C12N15/09 , A61K38/00 , A61K39/00 , A61K39/395 , A61K39/44 , A61P1/04 , A61P1/16 , A61P1/18 , A61P3/10 , A61P5/14 , A61P13/12 , A61P17/00 , A61P17/06 , A61P19/02 , A61P21/04 , A61P25/00 , A61P35/02 , A61P37/02 , A61P37/06 , A61P43/00 , C07K16/28 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12P21/02 , C12Q1/02 , A61P37/00 , G01N33/53
CPC分类号： C07K16/2833 , A61K2039/505 , C07K16/28 , C07K2317/21 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/76
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3.发明公开ANTIBODIES THAT BLOCK RECEPTOR PROTEIN TYROSINE KINASE ACTIVATION, METHODS OF SCREENING FOR AND USES THEREOF 有权受体酪氨酸激酶活化蛋白封闭抗体，用于筛选FACT及其用途
公开(公告)号：EP1423428A4
公开(公告)日：2005-06-22
申请号：EP02741132
申请日：2002-06-20
申请人： PROCHON BIOTECH LTD , MORPHOSYS AG
发明人： YAYON AVNER , ROM ERAN , THOMASSEN-WOLF ELISABETH , BORGES ERIC
IPC分类号： G01N33/50 , A61K38/00 , A61K39/395 , A61K48/00 , A61P17/06 , A61P19/00 , A61P27/02 , A61P27/06 , A61P35/00 , A61P35/04 , C07K16/28 , C07K16/30 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/13 , C12Q1/48 , G01N33/15 , C07K16/00 , A61K38/17 , C12N15/10 , C12Q1/00
CPC分类号： C07K16/3038 , A61K38/00 , A61K2039/505 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2319/30
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