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公开(公告)号：EP3470535B1
公开(公告)日：2020-04-01
申请号：EP18190058.0
申请日：2004-06-17
发明人： BRYANT, John L. , PAIK, Soonmyung , BAKER, Joffre , SHAK, Steve
IPC分类号： C12Q1/6886
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公开(公告)号：EP3470535A1
公开(公告)日：2019-04-17
申请号：EP18190058.0
申请日：2004-06-17
发明人： BRYANT, John L. , PAIK, Soonmyung , BAKER, Joffre , SHAK, Steve
IPC分类号： C12Q1/6886
摘要： Abstract: The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of cancer, in particular of breast cancer.
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公开(公告)号：EP3179393B1
公开(公告)日：2020-07-08
申请号：EP16191856.0
申请日：2013-01-28
申请人： Genomic Health, Inc.
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4.发明授权TESTS TO PREDICT RESPONSIVENESS OF CANCER PATIENTS TO CHEMOTHERAPY TREATMENT OPTIONS 有权测试为癌症患者的治疗方案化疗的预测应答率
公开(公告)号：EP2294215B1
公开(公告)日：2013-01-16
申请号：EP09747388.8
申请日：2009-05-12
申请人： Genomic Health, Inc. , Aventis Inc.
IPC分类号： C12Q1/68 , G01N33/53 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , G01N33/574 , G01N33/57415 , G01N2333/705 , G01N2333/72 , G01N2800/52 , G01N2800/60
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5.发明公开GENE EXPRESSION PROFILE ALGORITHM AND TEST FOR DETERMINING PROGNOSIS OF PROSTATE CANCER 审中-公开基因表达谱简介及测定前列腺癌预后的实验研究
公开(公告)号：EP3179393A2
公开(公告)日：2017-06-14
申请号：EP16191856.0
申请日：2013-01-28
申请人： Genomic Health, Inc.
发明人： SHAK, Steve , LEE, Mark , NOVOTNY, William , MADDALA, Tara , CRAGER, Michael , CHERBAVAZ, Diana , PELHAM, Robert , MILLWARD, Carl L. , KNEZEVIC, Dejan
摘要： The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes, or their co-expressed genes, from a biological sample obtained from a prostate cancer patient. The genes may be grouped into functional gene subsets for calculating a quantitative score useful to predict a likelihood of a clinical outcome for a prostate cancer patient.
摘要翻译： 本发明提供了基于算法的分子测定法，其涉及从获自前列腺癌患者的生物样品测量基因或其共表达基因的表达水平。 可将基因分组为功能基因亚组，用于计算可用于预测前列腺癌患者临床结果可能性的定量评分。
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公开(公告)号：EP1590487A2
公开(公告)日：2005-11-02
申请号：EP04708653.3
申请日：2004-02-05
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/158
摘要： The present invention concerns prognostic markers associated with cancer. In particular, the invention concerns prognostic methods based on the molecular charaterization of gene expression in paraffin-embedded, fixed samples of cancer tissue, which allow a physician to predict whether a patient is likely to respond well to treatment with an EGFR inhibitor.
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公开(公告)号：EP1587957A2
公开(公告)日：2005-10-26
申请号：EP04702177.9
申请日：2004-01-14
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/158
摘要： The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
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公开(公告)号：EP3115470A1
公开(公告)日：2017-01-11
申请号：EP16181799.4
申请日：2003-03-12
申请人： Genomic Health, Inc.
IPC分类号： C12Q1/68
CPC分类号： G01N33/57484 , C12N15/1003 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , G01N33/57415
摘要： The invention concerns sensitive methods to measure mRNA levels in biopsied tumor tissues, including archived paraffin-embedded biopsy material. The invention also concerns breast cancer gene sets important in the diagnosis and treatment of breast cancer, and methods for assigning the most optimal treatment options to breast cancer patient based upon knowledge derived for gene expression studies.
摘要翻译： 本发明涉及测量活检肿瘤组织中的mRNA水平的敏感方法，包括归档石蜡包埋的活检材料。 本发明还涉及在乳腺癌诊断和治疗中重要的乳腺癌基因集，以及基于为基因表达研究获得的知识为乳腺癌患者分配最佳治疗选择的方法。
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9.发明公开TESTS TO PREDICT RESPONSIVENESS OF CANCER PATIENTS TO CHEMOTHERAPY TREATMENT OPTIONS 有权测试为癌症患者的治疗方案化疗的预测应答率
公开(公告)号：EP2294215A1
公开(公告)日：2011-03-16
申请号：EP09747388.8
申请日：2009-05-12
申请人： Genomic Health, Inc. , Aventis Inc.
IPC分类号： C12Q1/68 , G01N33/53 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , G01N33/574 , G01N33/57415 , G01N2333/705 , G01N2333/72 , G01N2800/52 , G01N2800/60
摘要： The present disclosure provides methods and compositions to facilitate prediction of the likelihood of responsiveness of cancer patients to treatment including a taxane and/or a cyclophosphamide.
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公开(公告)号：EP1587957B1
公开(公告)日：2010-06-09
申请号：EP04702177.9
申请日：2004-01-14
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/158
摘要： The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
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