公开(公告)号：EP0973892A2

公开(公告)日：2000-01-26

申请号：EP98911597.7

申请日：1998-03-12

申请人： HUMAN GENOME SCIENCES, INC.

发明人： RUBEN, Steven, M. ,  ROSEN, Craig, A. ,  LI, Yi ,  ZENG, Zhizhen ,  KYAW, Hla ,  FISCHER, Carrie, L. ,  LI, Haodong ,  SOPPET, Daniel, R. ,  GENTZ, Reiner, L. ,  WEI, Ying, Fei ,  MOORE, Paul, A. ,  YOUNG, Paul, E. ,  GREENE, John, M. ,  FERRIE, Ann, M.

IPC分类号： C12N15/12 ,  C07K14/47 ,  C12Q1/68 ,  C12N1/21 ,  C12N15/62 ,  C07K19/00 ,  C12N5/10 ,  C07K16/18 ,  G01N33/60 ,  G01N33/68 ,  C12Q1/48 ,  G01N33/53 ,  A61K38/17 ,  A61K48/00 ,  A61K31/70 ,  C12N15/11

CPC分类号： C07K14/47 ,  A61K38/00 ,  A61K48/00 ,  A61K2039/53 ,  C07K14/4702 ,  C07K14/4718 ,  C07K2319/00 ,  C07K2319/02 ,  C12N2799/026

摘要： The present invention relates to 28 human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

公开(公告)号：EP1003763A1

公开(公告)日：2000-05-31

申请号：EP98939145.3

申请日：1998-07-29

申请人： HUMAN GENOME SCIENCES, INC.

发明人： RUBEN, Steven, M. ,  FENG, Ping ,  LAFLEUR, David, W. ,  MOORE, Paul, A. ,  SHI, Yanggu ,  KYAW, Hla ,  LI, Yi ,  ZENG, Zhizhen ,  CARTER, Kenneth, C. ,  ENDRESS, Gregory, A. ,  WEI, Ying-Fei ,  FAN, Ping ,  ROSEN, Craig, A.

IPC分类号： C07H19/00 ,  C12P19/34 ,  C12Q1/68

CPC分类号： C07K14/47 ,  A61K38/00

摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.