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公开(公告)号：EP2786709A1
公开(公告)日：2014-10-08
申请号：EP12853044.1
申请日：2012-11-09
Applicant: Hamamatsu Photonics K.K.
Inventor： SUZUKI Toshihiko , YAMASHITA Yutaka , UEDA Yukio , YAMAKI Etsuko , YAMASHITA Daisuke , YOSHIMOTO Kenji , SAKAHARA Harumi , OGURA Hiroyuki , NASU Hatsuko
CPC classification number: A61B5/0091 , A61B5/0035 , A61B5/708 , A61B8/0825 , A61B8/4416 , A61B2562/046 , A61B2562/146 , A61B2562/168 , G01N21/4795 , G01N2021/4797 , G01N2201/0826 , G01N2201/0833
Abstract: A mammography device 1 is an apparatus for acquiring internal information of a breast B of an examinee A by radiating light to the breast B and detecting the diffused light, and includes a container 3 configured to surround the breast B and a plurality of optical fibers 11 attached to be directed inward in the container 3 and configured to perform radiation and detection of light. The container 3 has a base member 30 having an opening 30a, a plurality of annular members 40 continuously disposed to come in communication with the opening 30a, and a bottom member 50 disposed inside the annular member 40 spaced the farthest distance from the base member 30. The annular members 40 and the bottom member 50 are configured to relatively displace the adjacent annular member 40 on the side of the base member 30 or the base member 30 in a communication direction. Some of the plurality of optical fibers 11 is attached to the plurality of annular members 40.
Abstract translation: 乳房摄影装置1是通过向乳房B照射光并检测漫射光来获取受检者A的乳房B的内部信息的装置，并且包括构成为包围乳房B的容器3和多根光纤11 被附着在向内指向容器3中并且被配置为执行光的辐射和检测。 容器3具有基部构件30，其具有开口30a，连续地设置成与开口30a连通的多个环形构件40和设置在与基部构件30最远距离的环形构件40内部的底部构件50 环状构件40和底部构件50构造成在相对于基部构件30或基部构件30的一个通信方向上相对地移动相邻的环形构件40。 多个光纤11中的一些被附接到多个环形构件40。
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2.发明公开
公开(公告)号：EP2730231A1
公开(公告)日：2014-05-14
申请号：EP12807701.3
申请日：2012-06-28
Applicant: Hamamatsu Photonics K.K.
Inventor： KUDO Hiroyuki , SAITO Naoya , UEDA Yukio , YOSHIMOTO Kenji , YAMASHITA Yutaka
CPC classification number: A61B5/7203 , A61B5/0073 , A61B5/0082 , A61B6/5247 , A61B8/15 , A61B8/5207 , A61B10/0041 , G01N21/4795 , G06T11/006
Abstract: The bioinstrumentation apparatus 10 includes a light irradiation unit irradiating a measurement region B with light, a light detection unit detecting diffused light from the measurement region, and a computing unit 14 generating a reconstructed image for the interior of the measurement region. The computing unit 14 calculates J coefficients w j set for every pixel of the reconstructed image and more than 0 and not more than 1 (where J is the number of pixels of the reconstructed image) and carries out successive approximation computation by the following iterative formula x j k + 1 = x j k + w j d j k
(where k is an integer from 1 to N, N is the number of times of iterative computation, x j (k) is a pixel value of the jth pixel on the kth iterative computation, and d j (k) is an update amount of the jth pixel on the kth iterative computation) to generate the reconstructed image. Thereby, there are provided a bioinstrumentation apparatus and an image generating method capable of suppressing a difference in spatial resolution and noise characteristics depending on a position inside the measurement region to generate an image which is uniform to a greater extent.Abstract translation: 生物仪器装置10包括用光照射测量区域B的光照射单元，检测来自测量区域的漫射光的光检测单元和产生测量区域内部的重建图像的计算单元14。 计算单元14计算重建图像的每个像素设定的J个系数wj，大于0且不大于1（其中J是重构图像的像素数），并通过以下迭代公式xjk进行逐次近似计算 + 1 = xjk + wj ¢djk（其中k是从1到N的整数，N是迭代计算的次数，xj（k）是第k次迭代计算中第j个像素的像素值，dj （k）是第k次迭代计算中的第j个像素的更新量）以生成重构图像。 因此，提供了一种能够根据测量区域内的位置来抑制空间分辨率和噪声特性的差异以生成更大程度上均匀的图像的生物仪器和图像生成方法。
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Patent Agency Ranking
公开(公告)号：EP2730231B1
公开(公告)日：2017-11-29
申请号：EP12807701.3
申请日：2012-06-28
Applicant: Hamamatsu Photonics K.K.
Inventor： KUDO Hiroyuki , SAITO Naoya , UEDA Yukio , YOSHIMOTO Kenji , YAMASHITA Yutaka
CPC classification number: A61B5/7203 , A61B5/0073 , A61B5/0082 , A61B6/5247 , A61B8/15 , A61B8/5207 , A61B10/0041 , G01N21/4795 , G06T11/006
Abstract: The bioinstrumentation apparatus 10 includes a light irradiation unit irradiating a measurement region B with light, a light detection unit detecting diffused light from the measurement region, and a computing unit 14 generating a reconstructed image for the interior of the measurement region. The computing unit 14 calculates J coefficients w j set for every pixel of the reconstructed image and more than 0 and not more than 1 (where J is the number of pixels of the reconstructed image) and carries out successive approximation computation by the following iterative formula x j k + 1 = x j k + w j �¢ d j k (where k is an integer from 1 to N, N is the number of times of iterative computation, x j (k) is a pixel value of the jth pixel on the kth iterative computation, and d j (k) is an update amount of the jth pixel on the kth iterative computation) to generate the reconstructed image. Thereby, there are provided a bioinstrumentation apparatus and an image generating method capable of suppressing a difference in spatial resolution and noise characteristics depending on a position inside the measurement region to generate an image which is uniform to a greater extent.
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4.发明公开METHOD AND DEVICE FOR MEASURING SCATTERING-ABSORPTION BODY 有权VERFAHREN UND VORRICHTUNG ZUR MESSUNG EINESSTREUUNGSABSORPTIONSKÖRPERS
公开(公告)号：EP2565622A1
公开(公告)日：2013-03-06
申请号：EP11774749.3
申请日：2011-03-29
Applicant: Hamamatsu Photonics K.K.
Inventor： YAMAKI Etsuko , YAMASHITA Yutaka , ODA Motoki , SUZUKI Hiroaki , SUZUKI Toshihiko , WATANABE Hiroshi , KOGA Shunsaku
CPC classification number: G01N21/17 , A61B5/14546 , A61B5/1455 , A61B2562/0242 , G01N21/359 , G01N21/49
Abstract: Light P of a predetermined wavelength irradiates one light incident position I set on the surface Ba of a scattering-absorption body B. The light P that propagates through the interior of the scattering-absorption body B is detected at one light detecting position D set on the surface Ba of the scattering-absorption body B, to yield a light detection signal. On the basis of this light detection signal, a temporal profile of the light intensity of the detected light is acquired, and on the basis of the temporal profile, an mean optical path length L of the light P in the interior of the scattering-absorption body B and information relating to the amount of substance to be measured in a region to be measured B1 are calculated. The information relating to the amount of substance to be measured is corrected on the basis of the mean optical path length L, such that the longer the mean optical path length L, the greater the amount of substance to be measured is. The method allows obtaining measurement results, exhibiting no influence of intervening tissue, to be obtained in accordance with a simple method.
Abstract translation: 预定波长的光P照射设置在散射吸收体B的表面Ba上的一个光入射位置I.在设置在散射吸收体B的一个光检测位置D处检测通过散射吸收体B的内部传播的光P 散射吸收体B的表面Ba，以产生光检测信号。 基于该光检测信号，获取检测光的光强度的时间分布，并且基于时间分布，散射吸收内部的光P的平均光程长度L 计算身体B和与待测区域B1中待测物质量有关的信息。 基于平均光路长度L校正与被测定物质量有关的信息，使得平均光程长度L越长，待测物质量越多。 该方法允许获得根据简单方法获得的测量结果，不显示介入组织的影响。
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公开(公告)号：EP2786709B1
公开(公告)日：2020-08-26
申请号：EP12853044.1
申请日：2012-11-09
Applicant: Hamamatsu Photonics K.K.
Inventor： SUZUKI Toshihiko , YAMASHITA Yutaka , UEDA Yukio , YAMAKI Etsuko , YAMASHITA Daisuke , YOSHIMOTO Kenji , SAKAHARA Harumi , OGURA Hiroyuki , NASU Hatsuko
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公开(公告)号：EP2565622B1
公开(公告)日：2018-10-31
申请号：EP11774749.3
申请日：2011-03-29
Applicant: Hamamatsu Photonics K.K.
Inventor： YAMAKI Etsuko , YAMASHITA Yutaka , ODA Motoki , SUZUKI Hiroaki , SUZUKI Toshihiko , WATANABE Hiroshi , KOGA Shunsaku
IPC: G01N21/359 , G01N21/49 , A61B5/1455 , A61B5/145
CPC classification number: G01N21/17 , A61B5/14546 , A61B5/1455 , A61B2562/0242 , G01N21/359 , G01N21/49
Abstract: Light P of a predetermined wavelength irradiates one light incident position I set on the surface Ba of a scattering-absorption body B. The light P that propagates through the interior of the scattering-absorption body B is detected at one light detecting position D set on the surface Ba of the scattering-absorption body B, to yield a light detection signal. On the basis of this light detection signal, a temporal profile of the light intensity of the detected light is acquired, and on the basis of the temporal profile, an mean optical path length L of the light P in the interior of the scattering-absorption body B and information relating to the amount of substance to be measured in a region to be measured B1 are calculated. The information relating to the amount of substance to be measured is corrected on the basis of the mean optical path length L, such that the longer the mean optical path length L, the greater the amount of substance to be measured is. The method allows obtaining measurement results, exhibiting no influence of intervening tissue, to be obtained in accordance with a simple method.
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公开(公告)号：EP2630917A1
公开(公告)日：2013-08-28
申请号：EP11834357.3
申请日：2011-10-18
Applicant: Hamamatsu Photonics K.K.
Inventor： SUZUKI Toshihiko , YAMASHITA Yutaka , UEDA Yukio , YAMAKI Etsuko , YAMASHITA Daisuke , YOSHIMOTO Kenji , SAKAHARA Harumi , OGURA Hiroyuki , NASU Hatsuko
CPC classification number: A61B8/5261 , A61B5/0035 , A61B5/0073 , A61B5/0091 , A61B5/4312 , A61B5/6835 , A61B5/708 , A61B5/72 , A61B5/7425 , A61B8/0825 , A61B8/14 , A61B8/406 , A61B8/4227 , A61B8/4281 , A61B8/4416 , A61B8/4444 , A61B8/4455 , A61B8/4477 , A61B8/5207 , A61B10/0041 , A61B2562/146
Abstract: A breast measurement apparatus 1 comprises a receptacle 3 for surrounding a breast B; a plurality of optical fibers 11 for irradiating the breast B with examination light and detecting transmitted scattered light from the breast B; an inner image generation unit 53 for generating an optical CT image concerning the breast B according to a detection signal of the transmitted scattered light; an ultrasonic probe 21, arranged so as to face the inside of the receptacle 3, for scanning the breast B with an ultrasonic wave and receiving a reflected wave from the breast B; an image generation unit 24 for generating an ultrasonic image concerning the breast B according to the reflected wave; and a mechanism for injecting and discharging a liquid interface agent I into and from the inside of the receptacle 3. This makes it possible to acquire an ultrasonic image and an optical CT image under the same measurement condition.
Abstract translation: 乳房测量装置1包括用于围绕乳房B的容器3; 多个光纤11，用于用检查光照射乳房B，并检测来自乳房B的透射散射光; 根据发送的散射光的检测信号生成与乳房B相关的光学CT图像的内部图像生成部53; 布置成面向容器3内部的超声波探头21，用于以超声波扫描乳房B并从乳房B接受反射波; 用于根据反射波产生与乳房B相关的超声波图像的图像生成单元24; 以及用于将液体界面剂I注入和排出到容器3的内部的机构。这使得可以在相同的测量条件下获取超声波图像和光学CT图像。
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