-
公开(公告)号：EP2786709B1
公开(公告)日：2020-08-26
申请号：EP12853044.1
申请日：2012-11-09
Applicant: Hamamatsu Photonics K.K.
Inventor： SUZUKI Toshihiko , YAMASHITA Yutaka , UEDA Yukio , YAMAKI Etsuko , YAMASHITA Daisuke , YOSHIMOTO Kenji , SAKAHARA Harumi , OGURA Hiroyuki , NASU Hatsuko
-
公开(公告)号：EP2630917A1
公开(公告)日：2013-08-28
申请号：EP11834357.3
申请日：2011-10-18
Applicant: Hamamatsu Photonics K.K.
Inventor： SUZUKI Toshihiko , YAMASHITA Yutaka , UEDA Yukio , YAMAKI Etsuko , YAMASHITA Daisuke , YOSHIMOTO Kenji , SAKAHARA Harumi , OGURA Hiroyuki , NASU Hatsuko
CPC classification number: A61B8/5261 , A61B5/0035 , A61B5/0073 , A61B5/0091 , A61B5/4312 , A61B5/6835 , A61B5/708 , A61B5/72 , A61B5/7425 , A61B8/0825 , A61B8/14 , A61B8/406 , A61B8/4227 , A61B8/4281 , A61B8/4416 , A61B8/4444 , A61B8/4455 , A61B8/4477 , A61B8/5207 , A61B10/0041 , A61B2562/146
Abstract: A breast measurement apparatus 1 comprises a receptacle 3 for surrounding a breast B; a plurality of optical fibers 11 for irradiating the breast B with examination light and detecting transmitted scattered light from the breast B; an inner image generation unit 53 for generating an optical CT image concerning the breast B according to a detection signal of the transmitted scattered light; an ultrasonic probe 21, arranged so as to face the inside of the receptacle 3, for scanning the breast B with an ultrasonic wave and receiving a reflected wave from the breast B; an image generation unit 24 for generating an ultrasonic image concerning the breast B according to the reflected wave; and a mechanism for injecting and discharging a liquid interface agent I into and from the inside of the receptacle 3. This makes it possible to acquire an ultrasonic image and an optical CT image under the same measurement condition.
Abstract translation: 乳房测量装置1包括用于围绕乳房B的容器3; 多个光纤11，用于用检查光照射乳房B，并检测来自乳房B的透射散射光; 根据发送的散射光的检测信号生成与乳房B相关的光学CT图像的内部图像生成部53; 布置成面向容器3内部的超声波探头21，用于以超声波扫描乳房B并从乳房B接受反射波; 用于根据反射波产生与乳房B相关的超声波图像的图像生成单元24; 以及用于将液体界面剂I注入和排出到容器3的内部的机构。这使得可以在相同的测量条件下获取超声波图像和光学CT图像。
-
公开(公告)号：EP3508123A1
公开(公告)日：2019-07-10
申请号：EP17846079.6
申请日：2017-08-08
Applicant: Saitama Medical University , Hamamatsu Photonics K.K.
Inventor： UEDA Shigeto , SAEKI Toshiaki , UEDA Yukio
IPC: A61B5/1455 , A61B10/00
Abstract: A method of evaluating a therapeutic effect of a drug in a cancer patient, comprising a comparison step of comparing a first absolute hemoglobin concentration in a sternum portion of the cancer patient before administration of the drug and a second absolute hemoglobin concentration in the sternum portion of the cancer patient after administration of the drug; and an evaluation step of evaluating the therapeutic effect of the drug in the cancer patient based on the result of comparison performed through the comparison step.
-
公开(公告)号：EP2786709A1
公开(公告)日：2014-10-08
申请号：EP12853044.1
申请日：2012-11-09
Applicant: Hamamatsu Photonics K.K.
Inventor： SUZUKI Toshihiko , YAMASHITA Yutaka , UEDA Yukio , YAMAKI Etsuko , YAMASHITA Daisuke , YOSHIMOTO Kenji , SAKAHARA Harumi , OGURA Hiroyuki , NASU Hatsuko
CPC classification number: A61B5/0091 , A61B5/0035 , A61B5/708 , A61B8/0825 , A61B8/4416 , A61B2562/046 , A61B2562/146 , A61B2562/168 , G01N21/4795 , G01N2021/4797 , G01N2201/0826 , G01N2201/0833
Abstract: A mammography device 1 is an apparatus for acquiring internal information of a breast B of an examinee A by radiating light to the breast B and detecting the diffused light, and includes a container 3 configured to surround the breast B and a plurality of optical fibers 11 attached to be directed inward in the container 3 and configured to perform radiation and detection of light. The container 3 has a base member 30 having an opening 30a, a plurality of annular members 40 continuously disposed to come in communication with the opening 30a, and a bottom member 50 disposed inside the annular member 40 spaced the farthest distance from the base member 30. The annular members 40 and the bottom member 50 are configured to relatively displace the adjacent annular member 40 on the side of the base member 30 or the base member 30 in a communication direction. Some of the plurality of optical fibers 11 is attached to the plurality of annular members 40.
Abstract translation: 乳房摄影装置1是通过向乳房B照射光并检测漫射光来获取受检者A的乳房B的内部信息的装置，并且包括构成为包围乳房B的容器3和多根光纤11 被附着在向内指向容器3中并且被配置为执行光的辐射和检测。 容器3具有基部构件30，其具有开口30a，连续地设置成与开口30a连通的多个环形构件40和设置在与基部构件30最远距离的环形构件40内部的底部构件50 环状构件40和底部构件50构造成在相对于基部构件30或基部构件30的一个通信方向上相对地移动相邻的环形构件40。 多个光纤11中的一些被附接到多个环形构件40。
-
Patent Agency Ranking5.发明公开
公开(公告)号：EP2730231A1
公开(公告)日：2014-05-14
申请号：EP12807701.3
申请日：2012-06-28
Applicant: Hamamatsu Photonics K.K.
Inventor： KUDO Hiroyuki , SAITO Naoya , UEDA Yukio , YOSHIMOTO Kenji , YAMASHITA Yutaka
CPC classification number: A61B5/7203 , A61B5/0073 , A61B5/0082 , A61B6/5247 , A61B8/15 , A61B8/5207 , A61B10/0041 , G01N21/4795 , G06T11/006
Abstract: The bioinstrumentation apparatus 10 includes a light irradiation unit irradiating a measurement region B with light, a light detection unit detecting diffused light from the measurement region, and a computing unit 14 generating a reconstructed image for the interior of the measurement region. The computing unit 14 calculates J coefficients w j set for every pixel of the reconstructed image and more than 0 and not more than 1 (where J is the number of pixels of the reconstructed image) and carries out successive approximation computation by the following iterative formula x j k + 1 = x j k + w j d j k
(where k is an integer from 1 to N, N is the number of times of iterative computation, x j (k) is a pixel value of the jth pixel on the kth iterative computation, and d j (k) is an update amount of the jth pixel on the kth iterative computation) to generate the reconstructed image. Thereby, there are provided a bioinstrumentation apparatus and an image generating method capable of suppressing a difference in spatial resolution and noise characteristics depending on a position inside the measurement region to generate an image which is uniform to a greater extent.Abstract translation: 生物仪器装置10包括用光照射测量区域B的光照射单元，检测来自测量区域的漫射光的光检测单元和产生测量区域内部的重建图像的计算单元14。 计算单元14计算重建图像的每个像素设定的J个系数wj，大于0且不大于1（其中J是重构图像的像素数），并通过以下迭代公式xjk进行逐次近似计算 + 1 = xjk + wj ¢djk（其中k是从1到N的整数，N是迭代计算的次数，xj（k）是第k次迭代计算中第j个像素的像素值，dj （k）是第k次迭代计算中的第j个像素的更新量）以生成重构图像。 因此，提供了一种能够根据测量区域内的位置来抑制空间分辨率和噪声特性的差异以生成更大程度上均匀的图像的生物仪器和图像生成方法。
-
公开(公告)号：EP4327753A1
公开(公告)日：2024-02-28
申请号：EP22815640.2
申请日：2022-03-17
Applicant: Hamamatsu Photonics K.K.
Inventor： SUZUKI Norihiro , UEDA Yukio
IPC: A61B10/00 , A61B5/1455
Abstract: A probe unit is a probe unit used to measure hemoglobin dynamics inside a subject, and the probe unit includes a main body having flexibility, a first probe attached to the main body and having a first face from which a first light emitting portion for irradiating the subject with light is exposed, a second probe attached to the main body to face the first probe and having a second face from which a first light incidence portion for detecting light propagated inside the subject is exposed, a first light shielding member having light shielding properties, containing an elastic material, and attached to the first face to surround an emission axis of the first light emitting portion, and a second light shielding member having light shielding properties, containing an elastic material, and attached to the second face to surround an incidence axis of the first light incidence portion.
-
公开(公告)号：EP3508124A1
公开(公告)日：2019-07-10
申请号：EP17846751.0
申请日：2017-09-04
Applicant: Hamamatsu Photonics K.K. , National University Corporation Hamamatsu University School of Medicine
Inventor： YOSHIMOTO Kenji , UEDA Yukio , OHMAE Etsuko , MIMURA Tetsuya , YOSHIZAWA Nobuko , NASU Hatsuko , OGURA Hiroyuki , SAKAHARA Harumi
IPC: A61B5/1455 , A61B10/00
Abstract: A biological measurement device includes a probe including a contact surface that includes a plurality of light input portions that input light to a measurement target part and a plurality of light receiving portions that receive measurement light output from the measurement target part, the contact surface being pressed against the measurement target part, and a calculation unit that calculates internal information on the basis of a result of detecting the measurement light obtained for each combination of the light input portion and the light receiving portion, wherein the plurality of light input portions and the plurality of light receiving portions constitute lattices having an interval d in a first direction and a second direction orthogonal to each other on the contact surface, at least some of the plurality of light receiving portions are located at a position separated by a distance A×d (A is an integer equal to or greater than 2) in the first direction and the second direction from the light input portion, at least some of the plurality of light input portions are located at a position separated by the distance A×d in the first direction and the second direction from the light receiving portion, and the combination is a combination in which an interval between the light input portion and the light receiving portion is the distance A×d.
-
公开(公告)号：EP2730231B1
公开(公告)日：2017-11-29
申请号：EP12807701.3
申请日：2012-06-28
Applicant: Hamamatsu Photonics K.K.
Inventor： KUDO Hiroyuki , SAITO Naoya , UEDA Yukio , YOSHIMOTO Kenji , YAMASHITA Yutaka
CPC classification number: A61B5/7203 , A61B5/0073 , A61B5/0082 , A61B6/5247 , A61B8/15 , A61B8/5207 , A61B10/0041 , G01N21/4795 , G06T11/006
Abstract: The bioinstrumentation apparatus 10 includes a light irradiation unit irradiating a measurement region B with light, a light detection unit detecting diffused light from the measurement region, and a computing unit 14 generating a reconstructed image for the interior of the measurement region. The computing unit 14 calculates J coefficients w j set for every pixel of the reconstructed image and more than 0 and not more than 1 (where J is the number of pixels of the reconstructed image) and carries out successive approximation computation by the following iterative formula x j k + 1 = x j k + w j �¢ d j k (where k is an integer from 1 to N, N is the number of times of iterative computation, x j (k) is a pixel value of the jth pixel on the kth iterative computation, and d j (k) is an update amount of the jth pixel on the kth iterative computation) to generate the reconstructed image. Thereby, there are provided a bioinstrumentation apparatus and an image generating method capable of suppressing a difference in spatial resolution and noise characteristics depending on a position inside the measurement region to generate an image which is uniform to a greater extent.
-
9.发明公开
公开(公告)号：EP3143940A1
公开(公告)日：2017-03-22
申请号：EP15792123.0
申请日：2015-04-28
Applicant: National University Corporation Hamamatsu University School of Medicine , Hamamatsu Photonics K.K.
Inventor： UEDA Yukio , YAMAKI Etsuko , SAKAHARA Harumi , OGURA Hiroyuki , NASU Hatsuko , YOSHIZAWA Nobuko
IPC: A61B10/00 , A61B5/1455 , A61B8/00
CPC classification number: A61B5/14546 , A61B5/1072 , A61B5/1455 , A61B5/14551 , A61B5/4312 , A61B5/708 , A61B5/7275 , A61B5/7278 , A61B8/00 , A61B8/0825 , A61B8/085 , A61B10/00 , A61B2562/04 , G06F19/00
Abstract: A breast measurement apparatus 1A includes a distance measurement unit 10 measuring a distance from a skin to a light absorption portion for a measurement region of a breast which is a normal region including no tumor or an object region including a tumor, a light measurement unit 15 measuring a hemoglobin amount in the measurement region by a light measurement method using measurement light of a predetermined wavelength, a correlation data storage unit 33 storing normal correlation data of the distance to the light absorption portion and a normal hemoglobin amount generated based on measurement results for normal regions, and an evaluation value calculation unit 35 calculating a property evaluation value of the tumor based on the normal hemoglobin amount, obtained from the normal correlation data and the distance to the light absorption portion in the object region, and an object hemoglobin amount in the object region. This realizes a breast measurement method and a measurement apparatus capable of improving measurement accuracy of a property of a tumor inside a breast.
Abstract translation: 乳房测量装置1A包括距离测量单元10，其测量作为包括肿瘤的正常区域或包括肿瘤的对象区域的乳房的测量区域的皮肤到光吸收部分的距离，光测量单元15 通过使用预定波长的测量光的光测量方法测量测量区域中的血红蛋白量;相关数据存储单元33，存储与光吸收部分的距离的正常相关数据和基于测量结果产生的正常血红蛋白量 正常区域和评估值计算单元35，根据从正常相关数据和到目标区域中的光吸收部分的距离获得的正常血红蛋白量，计算肿瘤的特性评估值，以及目标血红蛋白量 对象区域。 这实现了能够提高乳房内肿瘤特性的测量精度的乳房测量方法和测量装置。
-
-
-
-
-
-
-
-
Search Results
9
records
(took 0.013 seconds)
